scholarly journals Validation study for the hypothesis of internal mammary sentinel lymph node lymphatic drainage in breast cancer

Oncotarget ◽  
2016 ◽  
Vol 7 (27) ◽  
pp. 41996-42006 ◽  
Author(s):  
Bin-Bin Cong ◽  
Peng-Fei Qiu ◽  
Yan-Bing Liu ◽  
Tong Zhao ◽  
Peng Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Validation Study ◽  
Lymphatic Drainage ◽  
Internal Mammary

scholarly journals Precise intraoperative sentinel lymph node biopsies guided by lymphatic drainage in breast cancer

Oncotarget ◽  
2017 ◽  
Vol 8 (38) ◽  
pp. 63064-63072 ◽  
Author(s):  
Xiaoyan Li ◽  
Sisi Chen ◽  
Liyu Jiang ◽  
Xiaoli Kong ◽  
Tingting Ma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymphatic Drainage

scholarly journals Internal Mammary Sentinel Lymph Node Biopsy in Clinically Axillary Lymph Node-Positive Breast Cancer: Diagnosis and Implications for Patient Management

2019 ◽  
Vol 27 (2) ◽  
pp. 375-383 ◽  
Author(s):  
Peng-Fei Qiu ◽  
Rong-Rong Zhao ◽  
Wei Wang ◽  
Xiao Sun ◽  
Peng Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Therapeutic Strategy ◽  
Lymph Node Biopsy ◽  
Axillary Lymph ◽  
Nodal Staging ◽  
Node Biopsy ◽  
Initial Surgery ◽  
Internal Mammary

Abstract Background Routine performance of internal mammary sentinel lymph node biopsy (IM-SLNB) remains a subject of debate due to no clinical relevance in breast cancer, because it was performed only in clinically axillary lymph node (ALN)-negative patients. In this study, IM-SLNB was performed in clinically ALN-positive patients, and its impact on nodal staging and therapeutic strategy were subsequently analyzed. Methods Clinically ALN-positive patients who underwent IM-SLNB were enrolled in this prospective study. Statistical analysis was performed using Chi square test, Mann–Whitney U and logistic regression models with a significance level of 0.05. Results Among the 352 recruited patients, the internal mammary sentinel lymph node (IMSLN) visualization rate of patients who received initial surgery and neoadjuvant systemic therapy (NST) was 71.9% (123/171) and 33.1% (60/181), respectively. The 183 patients who underwent IM-SLNB successfully had the average time duration of 7 min and the median IMSLN number of 2. There were 87 positive IMSLNs in all the 347 removed IMSLNs, which were mainly concentrated in the second (50.6%) and third (34.5%) intercostal space. The IMSLN metastasis rate was 39.8% (initial surgery) and 13.3% (NST), respectively. All of the 183 IM-SLNB patients received more accurate nodal staging, 57 of whom had stage elevated, which might have prompted modifications to the therapeutic strategy. Conclusions IM-SLNB should be routinely performed in clinically ALN-positive patients, and thus more accurate nodal staging and perfect pathologic complete response definition could be put forward. The identification of IMLN metastases by IM-SLNB might potentially influence therapeutic strategies.

Pattern of lymphatic drainage to the sentinel lymph node in breast cancer patients

2000 ◽  
Vol 74 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Giuseppe Canavese ◽  
Marco Gipponi ◽  
Alessandra Catturich ◽  
Carmine Di Somma ◽  
Carlo Vecchio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Cancer Patients ◽  
Lymphatic Drainage ◽  
Breast Cancer Patients

A multicenter validation study of sentinel lymph node biopsy by the Japanese Breast Cancer Society

2000 ◽  
Vol 63 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Masakuni Noguchi ◽  
Kazuyoshi Motomura ◽  
Shigeru Imoto ◽  
Mitsuru Miyauchi ◽  
Kazuhiko Sato ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Validation Study ◽  
Lymph Node Biopsy ◽  
Cancer Society ◽  
Japanese Breast Cancer Society ◽  
Node Biopsy ◽  
Multicenter Validation
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