scholarly journals Marital status independently predicts pancreatic cancer survival in patients treated with surgical resection: an analysis of the SEER database

Oncotarget ◽  
2016 ◽  
Vol 7 (17) ◽  
pp. 24880-24887 ◽  
Author(s):  
Xiao-Dong Wang ◽  
Jian-Jun Qian ◽  
Dou-Sheng Bai ◽  
Zhen-Nan Li ◽  
Guo-Qing Jiang ◽  
...  
Oncotarget ◽  
2016 ◽  
Vol 7 (11) ◽  
pp. 13228-13235 ◽  
Author(s):  
Rong-liang Shi ◽  
Qian Chen ◽  
Zhen Yang ◽  
Gaofeng Pan ◽  
Ziping Zhang ◽  
...  

Author(s):  
Talha Ayaz ◽  
Saul Fredrickson ◽  
Kevin O’Mary ◽  
Megna A. Panchbhavi ◽  
Vinod K. Panchbhavi

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Wei Song ◽  
Chuan Tian

Background. Marital status has been reported to be a prognostic factor in multiple malignancies. However, its prognostic value on gastrointestinal stromal tumors (GISTs) have not yet been determined. The objective of the present analysis was to assess the effects of marital status on survival in patients with GISTs. Methods. The Surveillance, Epidemiology, and End Results (SEER) database was used to analyze 6195 patients who were diagnosed with GISTs from 2001 to 2014. We also use Kaplan-Meier analysis and Cox regression to analyze the impact of marital status on cancer-specific survival (CSS). Results. Patients in the married group had more frequency in white people, more high/moderate grade tumors, and were more likely to receive surgery. Widowed patients had a higher proportion of women, a greater proportion of older patients (>60 years), and more common site of the stomach. Multivariate analysis demonstrated that marital status was an independent prognostic factor for GISTs (P<0.001). Married patients had better CSS than unmarried patients (P<0.001). Subgroup analysis suggested that widowed patients had the lowest CSS compared with all other patients. Conclusions. Marital status is a prognostic factor for survival in patients with GISTs, and widowed patients are at greater risk of cancer-specific mortality.


PLoS Medicine ◽  
2016 ◽  
Vol 13 (8) ◽  
pp. e1002108 ◽  
Author(s):  
Livia S. Eberlin ◽  
Katherine Margulis ◽  
Ivette Planell-Mendez ◽  
Richard N. Zare ◽  
Robert Tibshirani ◽  
...  

2021 ◽  
Vol 7 ◽  
Author(s):  
Muhammad Nadeem Yousaf ◽  
Hamid Ehsan ◽  
Ahmad Muneeb ◽  
Ahsan Wahab ◽  
Muhammad K. Sana ◽  
...  

Pancreatic cancer is one of the most aggressive malignancies of the digestive tract and carries a poor prognosis. The majority of patients have advanced disease at the time of diagnosis. Surgical resection offers the only curative treatment, but only a small proportion of patients can undergo surgical resection. Radiofrequency ablation (RFA) is a well-known modality in the management of solid organ tumors, however, its utility in the management of pancreatic cancer is under investigation. Since the past decade, there is increasing use of RFA as it provides a feasible palliation treatment in the management of unresectable pancreatic cancer. RFA causes tumor cytoreduction through multiple mechanisms such as coagulative necrosis, protein denaturation, and activation of anticancer immunity. The safety profile of RFA is controversial because of the high risk for complications, however, small prospective and retrospective studies have shown promising results in its applicability for palliative management of unresectable pancreatic malignancies. In this review, we discuss different approaches of RFA, their indications, technical accessibility, safety, and major complications in the management of unresectable pancreatic cancer.


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