scholarly journals Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology

Oncotarget ◽  
2016 ◽  
Vol 7 (11) ◽  
pp. 12748-12760 ◽  
Author(s):  
James Che ◽  
Victor Yu ◽  
Manjima Dhar ◽  
Corinne Renier ◽  
Melissa Matsumoto ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Throughput

scholarly journals High-Throughput Automated Microscopy of Circulating Tumor Cells

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Carlos Aguilar-Avelar ◽  
Brenda Soto-García ◽  
Diana Aráiz-Hernández ◽  
Juan F. Yee-de León ◽  
Miguel Esparza ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Throughput ◽  
Integral Approach ◽  
Isolation And Characterization ◽  
Standard Clinical Practice ◽  
Automated Microscopy ◽  
Standard Marker

Abstract Circulating tumor cells (CTCs) have the potential of becoming the gold standard marker for cancer diagnosis, prognosis and monitoring. However, current methods for its isolation and characterization suffer from equipment variability and human operator error that hinder its widespread use. Here we report the design and construction of a fully automated high-throughput fluorescence microscope that enables the imaging and classification of cancer cells that were labeled by immunostaining procedures. An excellent agreement between our machine vision-based approach and a state-of-the-art microscopy equipment was achieved. Our integral approach provides a path for operator-free and robust analysis of cancer cells as a standard clinical practice.

scholarly journals Arrays of high-aspect ratio microchannels for high-throughput isolation of circulating tumor cells (CTCs)

2013 ◽  
Vol 20 (10-11) ◽  
pp. 1815-1825 ◽  
Author(s):  
Mateusz L. Hupert ◽  
Joshua M. Jackson ◽  
Hong Wang ◽  
Małgorzata A. Witek ◽  
Joyce Kamande ◽  
...  
Keyword(s):  
Aspect Ratio ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Throughput ◽  
High Aspect Ratio

scholarly journals Clinical Validation of an Ultra High-Throughput Spiral Microfluidics for the Detection and Enrichment of Viable Circulating Tumor Cells

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e99409 ◽  
Author(s):  
Bee Luan Khoo ◽  
Majid Ebrahimi Warkiani ◽  
Daniel Shao-Weng Tan ◽  
Ali Asgar S. Bhagat ◽  
Darryl Irwin ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Throughput ◽  
Clinical Validation

Abstract 1144: High-throughput genetic and expression analysis of circulating tumor cells

2010 ◽  
Author(s):  
AmirAli H. Talasaz ◽  
Gordon Cann ◽  
Zulfiqar Gulzar ◽  
Jing Chen ◽  
Craig April ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Expression Analysis ◽  
High Throughput

Abstract 444: Continuous, high throughput microfluidic device to monitor circulating tumor cells in cancer patients

2019 ◽  
Author(s):  
Kaylee Smith ◽  
Tae Hyun Kim ◽  
Costanza Paoletti ◽  
Douglas H. Thamm ◽  
Daniel F. Hayes ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Microfluidic Device ◽  
High Throughput

scholarly journals An Automated High-Throughput Counting Method for Screening Circulating Tumor Cells in Peripheral Blood

2013 ◽  
Vol 85 (4) ◽  
pp. 2465-2471 ◽  
Author(s):  
Mengxia Zhao ◽  
Perry G. Schiro ◽  
Jason S. Kuo ◽  
Karen M. Koehler ◽  
Daniel E. Sabath ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Throughput ◽  
Peripheral Blood ◽  
Counting Method
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