scholarly journals Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice

Oncotarget ◽  
2016 ◽  
Vol 7 (8) ◽  
pp. 8640-8652 ◽  
Author(s):  
Wakana Onuma ◽  
Susumu Tomono ◽  
Shinngo Miyamoto ◽  
Gen Fujii ◽  
Takahiro Hamoya ◽  
...  
Keyword(s):  
Mutant Mice ◽  
Intestinal Polyp ◽  
Irsogladine Maleate

scholarly journals Theracurmin inhibits intestinal polyp development in Apc ‐mutant mice by inhibiting inflammation‐related factors

2020 ◽  
Vol 111 (4) ◽  
pp. 1367-1374 ◽  
Author(s):  
Saeko Adachi ◽  
Takahiro Hamoya ◽  
Gen Fujii ◽  
Takumi Narita ◽  
Masami Komiya ◽  
...  
Keyword(s):  
Mutant Mice ◽  
Related Factors ◽  
Intestinal Polyp

New insights into heparan sulphate biosynthesis from the study of mutant mice

2002 ◽  
Vol 69 ◽  
pp. 47-57 ◽  
Author(s):  
Catherine L. R. Merry ◽  
John T. Gallagher
Keyword(s):  
Growth Factors ◽  
Biosynthetic Pathway ◽  
Heparan Sulphate ◽  
Mutant Mice ◽  
Gene Products ◽  
Multiple Gene ◽  
Adhesion Proteins ◽  
Ligand Interactions

Heparan sulphate (HS) is an essential co-receptor for a number of growth factors, morphogens and adhesion proteins. The biosynthetic modifications involved in the generation of a mature HS chain may determine the strength and outcome of HS–ligand interactions. These modifications are catalysed by a complex family of enzymes, some of which occur as multiple gene products. Various mutant mice have now been generated, which lack the function of isolated components of the HS biosynthetic pathway. In this discussion, we outline the key findings of these studies, and use them to put into context our own work concerning the structure of the HS generated by the Hs2st-/- mice.

Author response for "Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery"

2018 ◽  
Author(s):  
Alicia S. Wilson ◽  
Hsei Di Law ◽  
Christiane B. Knobbe‐Thomsen ◽  
Conor J. Kearney ◽  
Jane Oliaro ◽  
...  
Keyword(s):  
Th17 Cell ◽  
Mutant Mice ◽  
Author Response
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