scholarly journals Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and their function in breast cancer cells

Oncotarget ◽  
2015 ◽  
Vol 6 (33) ◽  
pp. 34475-34493 ◽  
Author(s):  
Andreas Ritter ◽  
Alexandra Friemel ◽  
Friderike Fornoff ◽  
Mouhib Adjan ◽  
Christine Solbach ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Adipose Derived Stem Cells ◽  
Adipose Tissues ◽  
Visceral Adipose

Expression profile of IL-8 and growth factors in breast cancer cells and adipose-derived stem cells (ASCs) isolated from breast carcinoma

2010 ◽  
Vol 265 (1) ◽  
pp. 80-85 ◽  
Author(s):  
Mahboobeh Razmkhah ◽  
Mansooreh Jaberipour ◽  
Ahmad Hosseini ◽  
Akbar Safaei ◽  
Behzad Khalatbari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Growth Factors ◽  
Breast Carcinoma ◽  
Cancer Cells ◽  
Expression Profile ◽  
Breast Cancer Cells ◽  
Adipose Derived Stem Cells

scholarly journals Promoting effects of adipose-derived stem cells on breast cancer cells are reversed by radiation therapy

2017 ◽  
Vol 70 (2) ◽  
pp. 701-711 ◽  
Author(s):  
Annemarie Baaße ◽  
Dajana Juerß ◽  
Elaine Reape ◽  
Katrin Manda ◽  
Guido Hildebrandt
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Radiation Therapy ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Adipose Derived Stem Cells

P006 Paracrine interaction between adipose-derived stem cells and breast cancer cells

The Breast ◽  
2015 ◽  
Vol 24 ◽  
pp. S27-S28
Author(s):  
W. Tsuji ◽  
R. Schweizer ◽  
J.A. Plock ◽  
K.G. Marra ◽  
J.P. Rubin
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Adipose Derived Stem Cells ◽  
Paracrine Interaction

scholarly journals Novel Assay Analyzing Tropism between Adipose-Derived Stem Cells and Breast Cancer Cells Reveals a Low Oncogenic Response

Breast Care ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. 278-288 ◽  
Author(s):  
Matthias A. Sauter ◽  
Elizabeth Brett ◽  
Christina M. Müller ◽  
Hans-Günther Machens ◽  
Dominik Duscher
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Cells ◽  
Clinical Data ◽  
Breast Cancer Cells ◽  
Fat Grafting ◽  
Boyden Chamber ◽  
Adipose Derived Stem Cells ◽  
The Novel ◽  
The Media

Introduction: In the surgical world of breast cancer reconstruction, fat grafting is commonly viewed as an oncogenic risk. Scientific studies add confusion, given the stark lack of clinical evidence suggesting pro-oncogenic links. Typically, classic migration assays (e.g., Boyden chamber) between adipose-derived stem cells and breast cancer cells define this cell relationship as pro-oncogenic. Objective: We sought to develop a new migration model which better explains existing clinical data. Methods: Silicon chambers were used to seed isolated populations of cells simultaneously in culture dish. Once cells had adhered, chambers were removed and cells were allowed to follow natural trophic cues. Multiple permutations of MDA-MB-231, MCF-7, HS-27, and ASCs were engineered. Cells were stained with MitoTracker for fluorescent visualization. A human cytokine array (RayBiotech) was performed on the media of migrating assays. Cellular tropism and blot intensity were quantitatively measured in Image J. Results: An in vitromodel was successfully constructed where ASCs reproducibly and freely migrated. Cytokine arrays reveal higher levels of IL-6 and CCL2 in the media of Boyden chambers containing ASCs and MDA-MB-231, compared to the novel assay, comprised of the same cell numbers, types, and incubation times. Conclusion: These data collectively show for the first time the attraction of ASCs to malignant breast cancer cells; a phenomenon which many ASC studies infer. The cytokine profile of the novel system described is less oncogenic than the commonly described Boyden chamber. These data integrate better into the clinical data, which fail to link cancer recurrence with fat grafting.

Observed Changes in the Morphology and Phenotype of Breast Cancer Cells in Direct Co-Culture with Adipose-Derived Stem Cells

2014 ◽  
Vol 134 (3) ◽  
pp. 414-423 ◽  
Author(s):  
Joern W. Kuhbier ◽  
Vesna Bucan ◽  
Kerstin Reimers ◽  
Sarah Strauss ◽  
Andrea Lazaridis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Adipose Derived Stem Cells
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