Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model

Devaraja Rajasekaran; Ayesha Siddiq; Jennifer L.S. Willoughby; Jessica M. Biagi; Lisa M. Christadore; Sarah A. Yunes; Rachel Gredler; Nidhi Jariwala; Chadia L. Robertson; Maaged A. Akiel; Xue-Ning Shen; Mark A. Subler; Jolene J. Windle; Scott E. Schaus; Paul B. Fisher; Ulla Hansen; Devanand Sarkar

doi:10.18632/oncotarget.4656

Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model

Oncotarget ◽

10.18632/oncotarget.4656 ◽

2015 ◽

Vol 6 (28) ◽

pp. 26266-26277 ◽

Cited By ~ 12

Author(s):

Devaraja Rajasekaran ◽

Ayesha Siddiq ◽

Jennifer L.S. Willoughby ◽

Jessica M. Biagi ◽

Lisa M. Christadore ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Late Sv40 Factor

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Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1121601109 ◽

2012 ◽

Vol 109 (12) ◽

pp. 4503-4508 ◽

Cited By ~ 23

Author(s):

T. J. Grant ◽

J. A. Bishop ◽

L. M. Christadore ◽

G. Barot ◽

H. G. Chin ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Transcription Factor ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Oncogene Addiction

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Novel small molecule inhibitors of the transcription factor ETS-1 and their antitumor activity against hepatocellular carcinoma

European Journal of Pharmacology ◽

10.1016/j.ejphar.2021.174214 ◽

2021 ◽

pp. 174214

Author(s):

Yamin Jie ◽

Guijun Liu ◽

Mingyan E ◽

Ying Li ◽

Guo Xu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Transcription Factor ◽

Antitumor Activity ◽

Small Molecule ◽

Small Molecule Inhibitors

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From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma

Planta Medica ◽

10.1055/s-2007-986722 ◽

2007 ◽

Vol 73 (09) ◽

Cited By ~ 1

Author(s):

VB Konkimalla ◽

VL Suhas ◽

NR Chandra ◽

E Gebhart ◽

T Efferth

Keyword(s):

Squamous Cell Carcinoma ◽

Targeted Therapy ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Natural Product ◽

Molecular Diagnostics ◽

Small Molecule ◽

Squamous Cell ◽

Molecular Targeted Therapy ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004750.54854 ◽

2002 ◽

Author(s):

Carol Otey

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of Identification of small molecule inhibitors of anthrax lethal factor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1016978.201559 ◽

2004 ◽

Author(s):

Kristina Downing

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Lethal Factor ◽

Anthrax Lethal Factor

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Faculty Opinions recommendation of Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017973.285766 ◽

2005 ◽

Author(s):

George Perry

Keyword(s):

Small Molecule ◽

Amyloid Beta ◽

Small Molecule Inhibitors

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Faculty Opinions recommendation of High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023153.264839 ◽

2005 ◽

Author(s):

Robert Kelley

Keyword(s):

T Cell ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

High Affinity

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Faculty Opinions recommendation of Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024840.292879 ◽

2005 ◽

Author(s):

Chandra Kumar

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Phosphoinositide Dependent Kinase

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Faculty Opinions recommendation of Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1069767.522696 ◽

2007 ◽

Author(s):

Kim Barrett

Keyword(s):

Cystic Fibrosis ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

In Vivo Studies ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Regulator Protein ◽

Cystic Fibrosis Transmembrane

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Faculty Opinions recommendation of Discovery and characterization of small molecule inhibitors of the BET family bromodomains.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13411091.14784061 ◽

2011 ◽

Author(s):

Martin Stahl

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

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