scholarly journals Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter

Oncotarget ◽  
2020 ◽  
Vol 11 (25) ◽  
pp. 2424-2437
Author(s):  
Rive Sarfstein ◽  
Haim Werner
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Insulin Receptor ◽  
Tumor Suppressor P53 ◽  
Insr Gene ◽  
Direct Binding

scholarly journals Tumor suppressor p53 regulates heparanase gene expression

Oncogene ◽  
2006 ◽  
Vol 25 (28) ◽  
pp. 3939-3947 ◽  
Author(s):  
L Baraz ◽  
Y Haupt ◽  
M Elkin ◽  
T Peretz ◽  
I Vlodavsky
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Tumor Suppressor P53

The Tumor Suppressor p53 Down-Regulates Glucose Transporters GLUT1 and GLUT4 Gene Expression

2004 ◽  
Vol 64 (7) ◽  
pp. 2627-2633 ◽  
Author(s):  
Fabiana Schwartzenberg-Bar-Yoseph ◽  
Michal Armoni ◽  
Eddy Karnieli
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Glucose Transporters ◽  
Tumor Suppressor P53 ◽  
Glut4 Gene Expression

T.47. Human Tumor Suppressor p53 Modulates HIV-1 Vif and Tat Functions: Implications in HIV-1 Gene Expression and Replication

2009 ◽  
Vol 131 ◽  
pp. S63-S64
Author(s):  
Vikas Sood ◽  
Rajesh Ranjan ◽  
V. Ramachandran ◽  
Akhil Banerjea
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Human Tumor ◽  
Tumor Suppressor P53 ◽  
Hiv 1

scholarly journals The Tumor Suppressor p53 Inhibits Net, an Effector of Ras/Extracellular Signal-Regulated Kinase Signaling

2004 ◽  
Vol 24 (3) ◽  
pp. 1132-1142 ◽  
Author(s):  
Koji Nakade ◽  
Hong Zheng ◽  
Gitali Ganguli ◽  
Gilles Buchwalter ◽  
Christian Gross ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Map Kinases ◽  
Specific Gene ◽  
Tumor Suppressor P53 ◽  
Extracellular Signal ◽  
Protein Map ◽  
Mitogen Activated Protein ◽  
Map Kinase Pathway

ABSTRACT The tumor suppressor function of p53 is linked to its ability to repress gene expression, but the mechanisms of specific gene repression are poorly understood. We report that wild-type p53 inhibits an effector of the Ras oncogene/mitogen-activated protein (MAP) kinase pathway, the transcription factor Net. Tumor-associated mutant p53s are less efficient inhibitors. p53 inhibits by preventing phosphorylation of Net by MAP kinases. Loss of p53 in vivo leads to increased Net phosphorylation in response to wound healing and UV irradiation of skin. Our results show that p53 can repress specific gene expression by inhibiting Net, a factor implicated in cell cycle entry.

Activation of tumor suppressor p53 gene expression by magnetic thymine-imprinted chitosan nanoparticles

2016 ◽  
Vol 52 (10) ◽  
pp. 2137-2140 ◽  
Author(s):  
Mei-Hwa Lee ◽  
James L. Thomas ◽  
Jian-Zhou Chen ◽  
Jeng-Shiung Jan ◽  
Hung-Yin Lin
Keyword(s):  
Gene Expression ◽  
Magnetic Nanoparticles ◽  
Tumor Suppressor ◽  
Hepg2 Cells ◽  
Chitosan Nanoparticles ◽  
P53 Gene ◽  
Tumor Suppressor P53

Chitosan nanoparticles imprinted with thymine (and containing magnetic nanoparticles for ease in separations) were found to have dramatic effects on the expression of p53 in HepG2 cells.

Gene expression ofcyclin-dependent kinase subunit Cks2is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73

FEBS Letters ◽  
2007 ◽  
Vol 581 (6) ◽  
pp. 1166-1172 ◽  
Author(s):  
Karen Rother ◽  
Markus Dengl ◽  
Jana Lorenz ◽  
Katrin Tschöp ◽  
Ralf Kirschner ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Tumor Suppressor P53 ◽  
Related Proteins
Sign in / Sign up

Export Citation Format

Share Document