scholarly journals Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy

Oncotarget ◽  
2018 ◽  
Vol 9 (31) ◽  
pp. 22113-22122 ◽  
Author(s):  
Hussein F. Aqbi ◽  
Liliya Tyutyunyk-Massey ◽  
Rebecca C. Keim ◽  
Savannah E. Butler ◽  
Theresa Thekkudan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Recurrence ◽  
Early Tumor ◽  
Early Tumor Recurrence

scholarly journals Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy

2016 ◽  
Vol 65 (4) ◽  
pp. 719-726 ◽  
Author(s):  
María Reig ◽  
Zoe Mariño ◽  
Christie Perelló ◽  
Mercedes Iñarrairaegui ◽  
Andrea Ribeiro ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
High Rate ◽  
Early Tumor ◽  
Early Tumor Recurrence

scholarly journals Association of Mortalin (HSPA9) with Liver Cancer Metastasis and Prediction for Early Tumor Recurrence

2007 ◽  
Vol 7 (2) ◽  
pp. 315-325 ◽  
Author(s):  
Xin Yi ◽  
John M. Luk ◽  
Nikki P. Lee ◽  
Jirun Peng ◽  
Xisheng Leng ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Tumor Recurrence ◽  
Cancer Metastasis ◽  
Early Tumor ◽  
Early Tumor Recurrence

scholarly journals An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

2009 ◽  
Vol 174 (6) ◽  
pp. 2023-2034 ◽  
Author(s):  
Agnieszka K. Witkiewicz ◽  
Abhijit Dasgupta ◽  
Federica Sotgia ◽  
Isabelle Mercier ◽  
Richard G. Pestell ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Tumor Recurrence ◽  
Breast Cancers ◽  
Human Breast ◽  
Poor Clinical Outcome ◽  
Caveolin 1 ◽  
Early Tumor ◽  
Early Tumor Recurrence

scholarly journals Seizure burden pre- and postresection of low-grade gliomas as a predictor of tumor progression in low-grade gliomas

2018 ◽  
Vol 6 (3) ◽  
pp. 209-217 ◽  
Author(s):  
Fernando Santos-Pinheiro ◽  
Mingjeong Park ◽  
Diane Liu ◽  
Lawrence N Kwong ◽  
Savannah Cruz ◽  
...  
Keyword(s):  
Seizure Frequency ◽  
Tumor Recurrence ◽  
Surgical Intervention ◽  
Tumor Resection ◽  
Frequency Change ◽  
Low Grade ◽  
Low Grade Gliomas ◽  
Before And After ◽  
Early Tumor ◽  
Early Tumor Recurrence

Abstract Background Low-grade gliomas (LGGs) are slow-growing, infiltrative tumors frequently associated with seizures. Predicting which patients will develop early tumor recurrence based on clinical indicators following initial surgical intervention remains a challenge. Seizure recurrence following surgery may be an early indicator of tumor recurrence, especially in patients presenting with increase in seizure frequency. Methods This study analyzed 148 patients meeting inclusion criteria (age >18 years, LGG diagnosis, at least 1 seizure event recorded before and after initial surgical intervention). All patients were treated at the Brain and Spine Center at The University of Texas MD Anderson Cancer Center from January 2000 to March 2013. Seizure frequency in a 6-month period before and after tumor resection was categorized as none, 1, few (2 to 3 seizures) or several (>3 seizures). Immediately postoperative seizures (up to 48 hours from surgery) were not included in the analysis. Results A total of 116 (78.4%) patients had seizures at initial presentation and most (95%) were started on antiepileptic drugs (AEDs). We found 2 clinical variables with a significant impact on progression-free survival (PFS): Higher seizure frequency during the 6-month postoperative period and seizure frequency increase between the 6-month pre- and the 6-month postoperative periods were both correlated to higher risk of early tumor recurrence (P = .007 and P = .004, respectively). Conclusion Seizure frequency following surgical resection of LGGs and the seizure frequency change between the 6-month preoperative and postoperative periods may serve as clinical predictors of early tumor recurrence in patients with LGGs who are also afflicted by seizures.

Sign in / Sign up

Export Citation Format

Share Document