scholarly journals A comparison of arterial spin labeling and dynamic susceptibility perfusion imaging for resection control in glioblastoma surgery

Oncotarget ◽  
2018 ◽  
Vol 9 (26) ◽  
pp. 18570-18577 ◽  
Author(s):  
Thomas Lindner ◽  
Hajrullah Ahmeti ◽  
Julia Juhasz ◽  
Michael Helle ◽  
Olav Jansen ◽  
...  
Keyword(s):  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Dynamic Susceptibility ◽  
Resection Control

scholarly journals Arterial spin labeling in the grading of brain gliomas: could it help?

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Ahmed A. ElBeheiry ◽  
Doaa M. Emara ◽  
Amany Abdel-Bary Abdel-Latif ◽  
Mohamed Abbas ◽  
Amal S. Ismail
Keyword(s):  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
High Morbidity ◽  
Low Grade ◽  
Dynamic Susceptibility ◽  
High Grade ◽  
Low Grade Gliomas ◽  
High Grade Gliomas ◽  
Brain Gliomas

Abstract Background Gliomas are characterized by high morbidity and mortality with low cure and high recurrence rates, which depends to a great degree on the angiogenesis of the tumor. Assessment of such angiogenesis by perfusion techniques is of utmost importance for the preoperative grading of gliomas. The purpose of this study was to assess the role of arterial spin labeling (ASL) perfusion as a non-contrast MRI technique in the grading of brain gliomas, in correlation with the dynamic susceptibility contrast perfusion imaging (DSC-PI). The study was carried out on 35 patients admitted to the Neurosurgery Department with MRI features of gliomas and sent for further perfusion imaging. Non-contrast ASL followed by DSC-PI was done for all cases. The final diagnosis of the cases was established by histopathology. Results Fourteen patients (14/35) had low-grade gliomas while twenty-one (21/35) had high-grade gliomas. In low-grade gliomas, four cases out of 14 were falsely graded as high-grade tumors showing hyperperfusion on ASL, three of which showed DSC-PI hypoperfusion. In high-grade gliomas, two cases out of 21 were interpreted as an indeterminate grade by ASL showing isoperfusion, however showed hyperperfusion on DSC-PI. ROC curve analysis showed ASL-derived rCBF > 2.08 to have 80.95% sensitivity, 85.71% specificity, and overall accuracy of 82.86% compared to 100% sensitivity, specificity, and accuracy of DSC-PI-derived rCBV and rCBF of > 1.1 and > 0.9, respectively. A significant positive correlation was noted between ASL and DSC-PI with correlation coefficient reaching r = 0.80 between ASL-rCBF and DSC-rCBF (p < 0.01) and r = 0.68 between ASL and DSC-rCBV (p < 0.01). Conclusions ASL is a relatively recent non-contrast perfusion technique that obtains results which are in fair agreement with the more established DSC perfusion imaging making it an alternative method for preoperative assessment of perfusion of gliomas, especially for patients with contraindications to contrast agents.

scholarly journals 3D GRASE PROPELLER: Improved image acquisition technique for arterial spin labeling perfusion imaging

2011 ◽  
Vol 66 (1) ◽  
pp. 168-173 ◽  
Author(s):  
Huan Tan ◽  
W. Scott Hoge ◽  
Craig A. Hamilton ◽  
Matthias Günther ◽  
Robert A. Kraft
Keyword(s):  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Image Acquisition ◽  
Spin Labeling ◽  
Acquisition Technique

scholarly journals Evaluation of the Antiangiogenic Effects of Octreotide on Growth Hormone-producing Pituitary Adenoma using Arterial Spin-labeling Perfusion Imaging

2015 ◽  
Vol 14 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Naoto SAKAI ◽  
Shuhei YAMASHITA ◽  
Yasuo TAKEHARA ◽  
Harumi SAKAHARA ◽  
Satoshi BABA ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Spin Labeling

scholarly journals Perfusion imaging with arterial spin labeling in acute encephalopathy with reduced subcortical diffusion following secondary generalized status epilepticus

2017 ◽  
Vol 9 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Kenta Takahara ◽  
Takato Morioka ◽  
Takafumi Shimogawa ◽  
Toshiyuki Amano ◽  
Aoi Kawakita ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Acute Encephalopathy
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