The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells

Harrison T. Supnick; Rodica P. Bunaciu; Andrew Yen

doi:10.18632/oncotarget.24275

The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells

Oncotarget ◽

10.18632/oncotarget.24275 ◽

2018 ◽

Vol 9 (11) ◽

pp. 9808-9824 ◽

Cited By ~ 4

Author(s):

Harrison T. Supnick ◽

Rodica P. Bunaciu ◽

Andrew Yen

Keyword(s):

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Enhancing effects of ceramide derivatives on 1,25-dihydroxyvitamin D3-induced differentiation of human HL-60 leukemia cells

Life Sciences ◽

10.1016/j.lfs.2007.09.035 ◽

2007 ◽

Vol 81 (25-26) ◽

pp. 1638-1644 ◽

Cited By ~ 16

Author(s):

Dong Soo Kim ◽

Seung Hyun Kim ◽

Ju Han Song ◽

Young-Tae Chang ◽

Seung Yong Hwang ◽

...

Keyword(s):

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Synergistic Induction of 1,25-Dihydroxyvitamin D3- and All-trans-Retinoic Acid-Induced Differentiation of HL-60 Leukemia Cells by Yomogin, a Sesquiterpene Lactone fromArtemisia princeps

Planta Medica ◽

10.1055/s-2002-34937 ◽

2002 ◽

Vol 68 (10) ◽

pp. 886-890 ◽

Cited By ~ 9

Author(s):

Seung Hyun Kim ◽

Tae Sung Kim

Keyword(s):

Retinoic Acid ◽

Sesquiterpene Lactone ◽

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3 ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid ◽

Synergistic Induction

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Potentiation of 1,25-dihydroxyvitamin D3-induced differentiation of human promyelocytic leukemia cells into monocytes by costunolide, a germacranolide sesquiterpene lactone

Biochemical Pharmacology ◽

10.1016/s0006-2952(02)01292-3 ◽

2002 ◽

Vol 64 (8) ◽

pp. 1233-1242 ◽

Cited By ~ 34

Author(s):

Seung H Kim ◽

So N Kang ◽

Hyeoung J Kim ◽

Tae S Kim

Keyword(s):

Sesquiterpene Lactone ◽

Promyelocytic Leukemia ◽

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells

Journal of Cellular Physiology ◽

10.1002/jcp.22449 ◽

2011 ◽

Vol 226 (5) ◽

pp. 1232-1240 ◽

Cited By ~ 4

Author(s):

Xuening Wang ◽

George P. Studzinski

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3 ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

Acute Myeloid

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Enhancing effect of indirubin derivatives on 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced differentiation of HL-60 leukemia cells

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.05.044 ◽

2006 ◽

Vol 14 (19) ◽

pp. 6752-6758 ◽

Cited By ~ 12

Author(s):

Seung Hyun Kim ◽

Si-Wouk Kim ◽

Soo Jeong Choi ◽

Yong-Chul Kim ◽

Tae Sung Kim

Keyword(s):

Retinoic Acid ◽

Leukemia Cells ◽

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

Enhancing Effect ◽

1,25 Dihydroxyvitamin D3 ◽

Trans Retinoic Acid ◽

All Trans Retinoic Acid

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Transcriptional regulation of the c-myc protooncogene by 1,25-dihydroxyvitamin D3 in HL-60 promyelocytic leukemia cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)61317-1 ◽

1987 ◽

Vol 262 (9) ◽

pp. 4104-4108

Author(s):

R.U. Simpson ◽

T. Hsu ◽

D.A. Begley ◽

B.S. Mitchell ◽

B.N. Alizadeh

Keyword(s):

Transcriptional Regulation ◽

Promyelocytic Leukemia ◽

Leukemia Cells ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Terminal Differentiation of Human Leukemia Cells (HL60) by a Combination of 1,25-Dihydroxyvitamin D3 and Retinoic Acid (All Trans or 9-Cis)

Vitamin D ◽

10.1515/9783110882513-149 ◽

1994 ◽

pp. 449-450

Keyword(s):

Retinoic Acid ◽

Terminal Differentiation ◽

Leukemia Cells ◽

Human Leukemia ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3 ◽

Human Leukemia Cells

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Expression of MAP3 kinase COT1 is up-regulated by 1,25-dihydroxyvitamin D3 in parallel with activated c-jun during differentiation of human myeloid leukemia cells

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/j.jsbmb.2010.03.016 ◽

2010 ◽

Vol 121 (1-2) ◽

pp. 395-398 ◽

Cited By ~ 8

Author(s):

Xuening Wang ◽

George P. Studzinski

Keyword(s):

Myeloid Leukemia ◽

Leukemia Cells ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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1,25-Dihydroxyvitamin D3 induces monocytic differentiation of human myeloid leukemia cells by regulating C/EBPβ expression through MEF2C

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/j.jsbmb.2014.11.016 ◽

2015 ◽

Vol 148 ◽

pp. 132-137 ◽

Cited By ~ 16

Author(s):

Ruifang Zheng ◽

Xuening Wang ◽

George P. Studzinski

Keyword(s):

Myeloid Leukemia ◽

Leukemia Cells ◽

Monocytic Differentiation ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells

Journal of Cellular Biochemistry ◽

10.1002/1097-4644(20010315)80:4<471::aid-jcb1001>3.0.co;2-j ◽

2001 ◽

Vol 80 (4) ◽

pp. 471-482 ◽

Cited By ~ 106

Author(s):

Xuening Wang ◽

George P. Studzinski

Keyword(s):

Induced Differentiation ◽

Dihydroxyvitamin D3 ◽

Hl60 Cells ◽

1,25 Dihydroxyvitamin D3 ◽

Extracellular Signal

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