scholarly journals Polymorphisms in four microRNAs and risk of oral squamous cell cancer: a meta-analysis

Oncotarget ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 8695-8705 ◽  
Author(s):  
Junfeng Zeng ◽  
Xiaowei Yi ◽  
Hao Liu ◽  
Yi Yang ◽  
Yuchen Duan ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Meta Analysis ◽  
Cell Cancer ◽  
Oral Squamous Cell Cancer

scholarly journals Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer

2017 ◽  
Vol 18 (4) ◽  
pp. 724 ◽  
Author(s):  
Nadia Ferlazzo ◽  
Monica Currò ◽  
Angelo Zinellu ◽  
Daniela Caccamo ◽  
Gaetano Isola ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Genetic Background ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Mgmt Methylation ◽  
Oral Squamous Cell Cancer

scholarly journals Effect of modern high-dose versus standard-dose radiation in definitive concurrent chemo-radiotherapy on outcome of esophageal squamous cell cancer: a meta-analysis

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
He-San Luo ◽  
He-Cheng Huang ◽  
Lian-Xing Lin
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Standard Dose ◽  
Meta Analysis ◽  
Cell Cancer ◽  
Esophageal Squamous Cell Cancer ◽  
High Dose ◽  
Radiotherapy Techniques ◽  
Dose Radiation ◽  
Modern Radiotherapy

Abstract Background and objectives Radiation Therapy Oncology Group (RTOG) 94–05 has demonstrated that higher dose radiation didn’t improve outcome of patients with esophageal cancer (EC). However, several retrospective studies showed that a higher dose radiation based on modern radiotherapy techniques could improve overall survival (OS) and local control rate (LCR) of patients with EC, especially esophageal squamous cell cancer (ESCC). As trials have provided updated and controversial data, we performed this updated meta-analysis to investigate whether high-dose (> = 60 Gy) radiotherapy in definitive concurrent chemo-radiotherapy (CCRT) could yield benefit compared to standard dose radiotherapy. Methods A systematic literature search was carried out in the database of MEDLINE, PubMed and Embase. All studies published between 1 January 1990 and 31 December 2018 on the association between radiation dose and curative efficiency in EC were included in this meta-analysis. The hazard ratio (HR) was used to evaluate the time-to-event data employing RevMan version 5.3. Results Eight articles with a total of 3736 patients were finally included. Results indicated that there was a significant benefit in favor of high dose radiotherapy (HD-RT) regarding OS (HR = 0.78, 95%CI: 0.72–0.84, p < 0.001; 2-year OS risk ratio (RR) = 1.25, 95%CI: 1.14–1.37, p < 0.001), progression-free survival (PFS) (P = 0.001, HR = 0.7, 95%CI: 0.57–0.87) and LRFS (P < 0.001, HR = 0.52, 95%CI: 0.36–0.74) . Conclusions HD-RT (> = 60 Gy) based on modern radiotherapy techniques in definitive CCRT appears to improve OS, PFS amd LRFS compared to the SD-RT in patients with ESCC.

scholarly journals Rising population of survivors of oral squamous cell cancer in the United States

Cancer ◽  
2016 ◽  
Vol 122 (9) ◽  
pp. 1380-1387 ◽  
Author(s):  
Mira A. Patel ◽  
Amanda L. Blackford ◽  
Eleni M. Rettig ◽  
Jeremy D. Richmon ◽  
David W. Eisele ◽  
...  
Keyword(s):  
United States ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
The United States ◽  
Oral Squamous Cell Cancer

scholarly journals Association between polymorphisms in pre-miRNA genes and risk of oral squamous cell cancer in a Chinese population

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0176044 ◽  
Author(s):  
Enjiao Zhang ◽  
Zhongfei Xu ◽  
Weiyi Duan ◽  
Shaohui Huang ◽  
Li Lu
Keyword(s):  
Squamous Cell ◽  
Chinese Population ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Mirna Genes ◽  
Oral Squamous Cell Cancer
Sign in / Sign up

Export Citation Format

Share Document