scholarly journals Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma

Oncotarget ◽  
2017 ◽  
Vol 8 (69) ◽  
pp. 113858-113873
Author(s):  
Hua Wang ◽  
Veerabhadran Baladandayuthapani ◽  
Zhiqiang Wang ◽  
Heather Lin ◽  
Zuzana Berkova ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Akt Signaling ◽  
Receptor Type ◽  
Gtpase Activating Protein ◽  
Truncated Protein ◽  
Protein Tyrosine ◽  
Iq Motif

scholarly journals Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

2021 ◽  
pp. jclinpath-2020-206927
Author(s):  
Maryam Ahmed Al Barashdi ◽  
Ahlam Ali ◽  
Mary Frances McMullin ◽  
Ken Mills
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Protein Tyrosine Kinase ◽  
Biological Activities ◽  
Tyrosine Phosphatase ◽  
Cell Types ◽  
Receptor Type ◽  
Future Research ◽  
Protein Tyrosine ◽  
Type C ◽  
Almost All

The leucocyte common antigen, protein tyrosine phosphatase receptor type C (PTPRC), also known as CD45, is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes, and is an essential regulator of T and B cell antigen receptor-mediated activation. Disruption of the equilibrium between protein tyrosine kinase and phosphatase activity (from CD45 and others) can result in immunodeficiency, autoimmunity, or malignancy. CD45 is normally present on the cell surface, therefore it works upstream of a large signalling network which differs between cell types, and thus the effects of CD45 on these cells are also different. However, it is becoming clear that CD45 plays an essential role in the innate immune system and this is likely to be a key area for future research. In this review of PTPRC (CD45), its structure and biological activities as well as abnormal expression of CD45 in leukaemia and lymphoma will be discussed.

scholarly journals Protein tyrosine phosphatase receptor type E (PTPRE) regulates the activation of wild-type KIT and KIT mutants differently

2021 ◽  
Vol 26 ◽  
pp. 100974
Author(s):  
Shaoting Zhang ◽  
Liangying Zhang ◽  
Zongying Jiang ◽  
Yue Guo ◽  
Hui Zhao ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Wild Type ◽  
Protein Tyrosine

scholarly journals Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance

2020 ◽  
Vol 11 ◽  
Author(s):  
Larissa Hering ◽  
Egle Katkeviciute ◽  
Marlene Schwarzfischer ◽  
Philipp Busenhart ◽  
Claudia Gottier ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Protein Tyrosine

PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome

2008 ◽  
Vol 40 (8) ◽  
pp. 946-948 ◽  
Author(s):  
Barbara Schormair ◽  
David Kemlink ◽  
Darina Roeske ◽  
Gertrud Eckstein ◽  
Lan Xiong ◽  
...  
Keyword(s):  
Restless Legs Syndrome ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Protein Tyrosine ◽  
Restless Legs

scholarly journals Characterization of the Activation of Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1 (PTPRZ1) by Hypoxia Inducible Factor-2 Alpha

PLoS ONE ◽  
2010 ◽  
Vol 5 (3) ◽  
pp. e9641 ◽  
Author(s):  
Victoria Wang ◽  
David A. Davis ◽  
Ravindra P. Veeranna ◽  
Muzammel Haque ◽  
Robert Yarchoan
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Hypoxia Inducible Factor ◽  
Receptor Type ◽  
Protein Tyrosine

scholarly journals Protein Tyrosine Phosphatase Non-Receptor Type 22 Modulates NOD2-Induced Cytokine Release and Autophagy

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e72384 ◽  
Author(s):  
Marianne R. Spalinger ◽  
Silvia Lang ◽  
Stephan R. Vavricka ◽  
Michael Fried ◽  
Gerhard Rogler ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Cytokine Release ◽  
Protein Tyrosine

scholarly journals Protein tyrosine phosphatase non-receptor type 14 is a novel sperm-motility biomarker

2011 ◽  
Vol 28 (9) ◽  
pp. 851-861 ◽  
Author(s):  
Hsin-Chih Albert Chao ◽  
Chia-Ling Chung ◽  
Hsien-An Pan ◽  
Pao-Chi Liao ◽  
Pao-Lin Kuo ◽  
...  
Keyword(s):  
Sperm Motility ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Receptor Type ◽  
Protein Tyrosine
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