scholarly journals A case-control study on risk factors of breast cancer in Han Chinese women

Oncotarget ◽  
2017 ◽  
Vol 8 (57) ◽  
pp. 97217-97230 ◽  
Author(s):  
Li-Yuan Liu ◽  
Fei Wang ◽  
Shu-De Cui ◽  
Fu-Guo Tian ◽  
Zhi-Min Fan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Han Chinese ◽  
Control Study

Dietary Choline Intake during Pregnancy and PEMT rs7946 Polymorphism on Risk of Preterm Birth: A Case-Control Study

2021 ◽  
pp. 1-10
Author(s):  
Jie Zhu ◽  
Yu-Hong Liu ◽  
Xiang-Long He ◽  
Martin Kohlmeier ◽  
Li-Li Zhou ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Han Chinese ◽  
Food Frequency ◽  
Term Delivery ◽  
Choline Intake ◽  
Dietary Choline ◽  
Control Study

<b><i>Introduction and Aims:</i></b> Choline-metabolizing genetic variation may interact with choline intake on fetal programming and pregnancy outcome. This case-control study aims to explore the association of maternal choline consumption and phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphism rs7946 with preterm birth risk. <b><i>Methods:</i></b> 145 Han Chinese women with preterm delivery and 157 Han Chinese women with term delivery were recruited in Shanghai. Dietary choline intake during pregnancy was assessed using a validated food frequency questionnaire. Additionally, DNA samples were genotyped for PEMT rs7946 (G5465A) with plasma homocysteine (Hcy) levels measured. <b><i>Results:</i></b> Compared with the lowest quartile of choline intake, women within the highest consumption quartile had adjusted odds ratio (aOR) for preterm birth of 0.48 (95% confidence interval, CI [0.24, 0.95]). There was a significant interaction between maternal choline intake and PEMT rs7946 (<i>p</i> for interaction = 0.04), where the AA genotype carriers who consumed the energy-adjusted choline &#x3c;255.01 mg/day had aOR for preterm birth of 3.75 (95% CI [1.24, 11.35]), compared to those with GG genotype and choline intake &#x3e;255.01 mg/day during pregnancy. Additionally, the greatest elevated plasma Hcy was found in the cases with AA genotype and choline consumption &#x3c;255.01 mg/day (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The AA genotype of PEMT rs7946 may be associated with increased preterm birth in these Han Chinese women with low choline intake during pregnancy.

scholarly journals 82P Risk factors for breast cancer: A case-control study among post-menopausal women in Pakistan

2016 ◽  
Vol 27 ◽  
pp. ix24
Author(s):  
N.A. Jadoon ◽  
M. Hussain ◽  
F.U. Sulehri ◽  
A. Zafar ◽  
A. Ijaz
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Control Study

Risk Factors for Male Breast Cancer: A Case Control Study in Alexandria, Egypt

2002 ◽  
Vol 32 (3) ◽  
pp. 459-470
Author(s):  
Fayek El Khwsky ◽  
Amal El Sodafy ◽  
Mohammed Saleem ◽  
Dalal El-Guiziry
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Male Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Male Breast ◽  
Control Study
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