scholarly journals Body mass index and incidence of nonaggressive and aggressive prostate cancer: a dose-response meta-analysis of cohort studies

Oncotarget ◽  
2017 ◽  
Vol 8 (57) ◽  
pp. 97584-97592 ◽  
Author(s):  
Bo Xie ◽  
Guanjun Zhang ◽  
Xiao Wang ◽  
Xin Xu
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Cohort Studies ◽  
Body Mass ◽  
Dose Response ◽  
Meta Analysis ◽  
Aggressive Prostate Cancer

Body mass index and mortality in prostate cancer patients: a dose–response meta-analysis

2016 ◽  
Vol 19 (2) ◽  
pp. 122-131 ◽  
Author(s):  
S Zhong ◽  
X Yan ◽  
Y Wu ◽  
X Zhang ◽  
L Chen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Mass Index ◽  
Cancer Patients ◽  
Body Mass ◽  
Dose Response ◽  
Meta Analysis

scholarly journals Body mass index and cancer risk in patients with type 2 diabetes: a dose–response meta-analysis of cohort studies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sepideh Soltani ◽  
Shima Abdollahi ◽  
Dagfinn Aune ◽  
Ahmad Jayedi
Keyword(s):  
Breast Cancer ◽  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Body Mass ◽  
Dose Response ◽  
Meta Analysis ◽  
Total Cancer

AbstractAlthough obesity has been associated with an increased cancer risk in the general population, the association in patients with type 2 diabetes (T2D) remains controversial. We conducted a dose–response meta-analysis of cohort studies of body mass index (BMI) and the risk of total and site-specific cancers in patients with T2D. A systematic literature search was conducted in PubMed, Scopus, and Medline until September 2020 for cohort studies on the association between BMI and cancer risk in patients with T2D. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects models. Ten prospective and three retrospective cohort studies (3,345,031 participants and 37,412 cases) were included in the meta-analysis. Each 5-unit increase in BMI (kg/m2) was associated with a 6% higher risk of total cancer (RR: 1.06, 95% CI 1.01, 1.10; I2 = 55.4%, n = 6), and with a 12% increased risk in the analysis of breast cancer (RR: 1.12, 95% CI 1.05, 1.20; I2 = 0%, n = 3). The pooled RRs showed no association with prostate cancer (RR: 1.02, 95% CI 0.92, 1.13; I2 = 64.6%, n = 4), pancreatic cancer (RR: 0.97, 95% CI 0.84, 1.11; I2 = 71%, n = 3), and colorectal cancer (RR: 1.05, 95% CI 0.98, 1.13; I2 = 65.9%, n = 2). There was no indication of nonlinearity for total cancer (Pnon-linearity = 0.99), however, there was evidence of a nonlinear association between BMI and breast cancer (Pnon-linearity = 0.004) with steeper increases in risk from a BMI around 35 and above respectively. Higher BMI was associated with a higher risk of total, and breast cancer but not with risk of other cancers, in patients with T2D, however, further studies are needed before firm conclusions can be drawn.

scholarly journals Association of body mass index with bladder cancer risk: a dose-response meta-analysis of prospective cohort studies

Oncotarget ◽  
2017 ◽  
Vol 8 (20) ◽  
pp. 33990-34000 ◽  
Author(s):  
Limin Zhao ◽  
Xiaoqin Tian ◽  
Xueyan Duan ◽  
Yongxiu Ye ◽  
Min Sun ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Bladder Cancer ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Body Mass ◽  
Dose Response ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Bladder Cancer Risk ◽  
Prospective Cohort Studies
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