scholarly journals Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies

Oncotarget ◽  
2017 ◽  
Vol 8 (48) ◽  
pp. 84459-84472 ◽  
Author(s):  
Zheng He ◽  
Ting-Ting Zhao ◽  
Hui-Mian Xu ◽  
Zhen-Ning Wang ◽  
Ying-Ying Xu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Prospective Cohort Studies

scholarly journals Alcohol consumption and gastric cancer risk: a meta-analysis of prospective cohort studies

Oncotarget ◽  
2017 ◽  
Vol 8 (47) ◽  
pp. 83237-83245 ◽  
Author(s):  
Xue Han ◽  
Li Xiao ◽  
Yao Yu ◽  
Yu Chen ◽  
Hai-Hua Shu
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Gastric Cancer Risk ◽  
Prospective Cohort Studies

scholarly journals Pickled Vegetable and Salted Fish Intake and the Risk of Gastric Cancer: Two Prospective Cohort Studies and a Meta-Analysis

Cancers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 996
Author(s):  
Jin Young Yoo ◽  
Hyun Jeong Cho ◽  
Sungji Moon ◽  
Jeoungbin Choi ◽  
Sangjun Lee ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cohort Studies ◽  
Cancer Incidence ◽  
Dose Response ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Fish Intake ◽  
Salted Fish ◽  
Prospective Cohort Studies ◽  
Increased Risk

An increased risk of gastric cancer for pickled vegetable and salted fish intake has been suggested, yet the lack of a dose-response association warrants a quantitative analysis. We conducted a meta-analysis, combining results from our analysis of two large Korean cohort studies and those from previous prospective cohort studies. We investigated the association of pickled vegetable and salted fish intake with gastric cancer in the Korean Genome Epidemiology Study and the Korean Multi-center Cancer Cohort Study using Cox proportional hazard models. We then searched for observational studies published until November 2019 and conducted both dose-response and categorical meta-analyses. The pooled relative risk (RR) of gastric cancer incidence was 1.15 (95% Confidence Interval (CI), 1.07–1.23) for 40 g/day increment in pickled vegetable intake in a dose-response manner (P for nonlinearity = 0.11). As for salted fish intake, the pooled risk of gastric cancer incidence was 1.17 (95% CI, 0.99–1.38) times higher, comparing the highest to the lowest intake. Our findings supported the evidence that high intake of pickled vegetable and salted fish is associated with elevated risk of gastric cancer incidence.

scholarly journals Coffee consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Liqing Li ◽  
Yong Gan ◽  
Chunmei Wu ◽  
Xianguo Qu ◽  
Gang Sun ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Prospective Cohort Studies

scholarly journals Efficacy and Long-Term Safety of H. pylori Eradication for Gastric Cancer Prevention

Cancers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 593 ◽  
Author(s):  
Jyh-Ming Liou ◽  
Yi-Chia Lee ◽  
Emad M. El-Omar ◽  
Ming-Shiang Wu
Keyword(s):  
Gastric Cancer ◽  
Antibiotic Resistance ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Eradication Therapy ◽  
Prospective Cohort Studies ◽  
Gastric Cancer Prevention ◽  
H Pylori

Helicobacter pylori (H. pylori) has been shown to be a causal factor of gastric cancer in cohort studies and animal models. Meta-analysis of case-control studies nested within prospective cohorts showed that H. pylori infection was associated with a 5.9-fold increased risk of non-cardia gastric cancer. Prospective cohort studies showed that gastric cancer developed in 1–4% of H. pylori-infected subjects. Gastric cancer was successfully induced in Mongolian gerbils and insulin-gastrin (INS-GAS) transgenic mice after inoculation of H. pylori. Meta-analysis of randomized control trials also showed that eradication of H. pylori may reduce the risk of gastric cancer. However, there are several concerns regarding the widespread use of antibiotics to prevent gastric cancer, including the emergence of antibiotic resistance and the perturbation of gut microbiota after H. pylori eradication. Recent studies showed that eradication of H. pylori resulted in an increase in the bacterial diversity and restoration of the relative abundance of other bacteria to levels similar to H. pylori non-infected subjects in the gastric microbiota. The administration of antibiotics may also alter the composition of intestinal microbiota. The α-diversity and β-diversity of fecal microbiota are significantly altered immediately after H. pylori eradication but are gradually restored to levels similar to those before therapy. Yet, the rate of recovery varies with regimens. The diversity was restored at week 8 after triple therapy but was not yet fully recovered at 1 year after concomitant and quadruple therapies. Some studies showed that supplementation of probiotics may reduce the dysbiosis during H. pylori eradication therapy. Although some earlier studies showed high levels of macrolide resistance after triple therapy, recent studies showed that the increased antibiotic resistance rate may be restored 2–12 months after eradication therapy. These results collectively provide evidence of the long-term safety of H. pylori eradication. Yet, more prospective cohort studies and randomized trials are warranted to assess the efficacy and long-term safety of H. pylori eradication for gastric cancer prevention.

scholarly journals The Dose-Response Relationship between Alcohol Consumption and the Risk of Type 2 Diabetes among Asian Men: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Manman Han
Keyword(s):  
Alcohol Consumption ◽  
Cohort Studies ◽  
Dose Response ◽  
Prospective Cohort ◽  
Alcohol Intake ◽  
Meta Analysis ◽  
Prospective Cohort Studies ◽  
Increased Risk ◽  
Asian Men

The objective of this review was to provide a summary of the literature on the dose-response relationship between alcohol consumption and risk of type 2 diabetes (T2D) in Asian populations, particularly men. The present study was recorded in PROSPERO as CRD 42019121073. We searched the PubMed-Medline, Web of Science, and Cochrane Library for studies published in any language since the database inception to January 2019. Prospective cohort studies were included in the meta-analysis. Relative risks (RRs) and 95% confidence intervals (CIs) were calculated for random-effects models and dose-response meta-analyses. In total, 8 prospective cohort studies were included. High alcohol intake was significantly associated with increased risk of T2D (RR=1.16, 95% CI: 1.04–1.29; Q statistic p=0.326) compared to the lowest category of alcohol intake. Nonlinear association was observed between alcohol consumption and T2D risk in men (p=0.003). Dose-wise, consuming ≤57 g/day of alcohol was not associated with the risk of T2D in this study; however, alcohol intake >57 g/day was associated with increased risk of T2D in men. Overall, the association between alcohol consumption and T2D among Asian men was J-shaped. Lifestyle recommendations for prevention of T2D should include advice on limiting alcohol intake. This trial is registered with Prospero registration: CRD 42019121073.

scholarly journals Effect of Coffee Consumption on the Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0128501 ◽  
Author(s):  
Haibin Liu ◽  
Ying Hua ◽  
Xiangyun Zheng ◽  
Zhaojun Shen ◽  
Hui Luo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Prospective Cohort Studies

scholarly journals Dietary Salt Intake and Gastric Cancer Risk: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Bo Wu ◽  
Dehua Yang ◽  
Shuhan Yang ◽  
Guangzhe Zhang
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Salt Intake ◽  
Meta Analysis ◽  
Processed Meat ◽  
Gastric Cancer Risk ◽  
Prospective Cohort Studies

The results of prospective cohort studies regarding the role of salt intake and subsequent gastric cancer risk are inconsistent. Thus, we performed a systematic review and meta-analysis to summarize the strength of the association of salt intake with gastric cancer morbidity and mortality. PubMed, EmBase, and Cochrane Library were systematically searched to identify eligible studies published throughout September 2021. The effect estimates with 95% confidence intervals (CIs) for gastric cancer morbidity or mortality in each study were applied to calculate the pooled results; these analyses were performed using the random-effects model. Twenty-six prospective cohort studies involving 4,956,350 individuals were selected; these studies reported 19,301 cases of gastric cancer and 2,871 cases of gastric cancer-associated mortality. High (RR: 1.25; 95%CI: 1.10–1.41; P = 0.001) or moderate (RR: 1.20; 95%CI: 1.04–1.38; P = 0.012) salt intake was associated with a greater risk of gastric cancer. High pickled food intake was associated with an increased gastric cancer risk (RR: 1.28; 95%CI: 1.05–1.57; P = 0.017), while moderate pickled foods intake had no significant effect on gastric cancer risk (RR: 1.10; 95%CI: 0.88–1.37; P = 0.390). Neither high (RR: 1.14; 95%CI: 0.95–1.36; P = 0.161) nor moderate (RR: 1.10; 95%CI: 0.87–1.40; P = 0.436) salted fish intake were associated with gastric cancer risk. A high intake of processed meat was significantly associated with a higher risk of gastric cancer (RR: 1.24; 95%CI: 1.03–1.49; P = 0.023), while moderate processed meat intake had no significant effect on the gastric cancer risk (RR: 1.01; 95%CI: 0.92–1.11; P = 0.844). High (RR: 1.04; 95%CI: 0.90–1.19; P = 0.626) and moderate (RR: 1.02; 95%CI: 0.94–1.11; P = 0.594) miso-soup intake had no effects on the gastric cancer risk. High intakes of salt, pickled food, and processed meat are associated with significantly increased risks of gastric cancer; these increased risks are also seen when participants consumed moderate amounts of salt.

Sign in / Sign up

Export Citation Format

Share Document