scholarly journals Long-term prognosis of Guillain-Barré syndrome not determined by treatment options?

Oncotarget ◽  
2017 ◽  
Vol 8 (45) ◽  
pp. 79991-80001 ◽  
Author(s):  
Ying Wang ◽  
Wenjuan Lang ◽  
Yaqian Zhang ◽  
Xiaoyi Ma ◽  
Chunkui Zhou ◽  
...  
Keyword(s):  
Treatment Options ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Long Term Prognosis ◽  
Guillain Barré

scholarly journals The clinical features and long-term prognosis of asymmetry childhood Guillain-Barré syndrome: a 5-year follow-up.

2020 ◽  
Author(s):  
Rui-Di Sun ◽  
jun Jiang
Keyword(s):  
Infectious Disease ◽  
Clinical Features ◽  
Guillain Barre Syndrome ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Guillain Barré Syndrome ◽  
Motor Nerves ◽  
Long Term Prognosis ◽  
Guillain Barré

Abstract Backgroud: The aim was to investigate clinical features and long-term prognosis of asymmetric childhood Guillain-Barré syndrome (GBS). Methods: In a retrospective cohort study, standardized data from all children with GBS seen at the Wuhan Children’s Hospital were collected regarding clinical presentation, auxiliary examinations and long-term outcome. We compared asymmetry GBS with symmetry GBS. Asymmetry GBS was defined by Medical Research Council (MRC) grade and motor nerves conduction in bilateral limbs. Recovery was defined as a return to normal life with a DSS of 0. Results: GBS was diagnosed in 72 children. 12（16.67%）were asymmetry GBS compared to 60 symmetry GBS . In asymmetry GBS, six children were transient asymmetry weakness and six children were persistent asymmetry weakness. Compared to symmetry weakness GBS, asymmetry weakness GBS had more preschool children (75% vs 25%, P=0.005), longer days on hospital(26.5(15-37) days vs 11(9-15) days, p =0.000), more mechanical ventilation(MV) (50% vs 8.33%, p=0.000), higher Disease severity score(DSS)at nadir of disease(4(3-5) vs 3(1-4), p=0.010), more axonal subtypes(50% vs 15%, p=0.013) and more complications(58.33% vs 8.33%, p=0.000). Eight children had sequelae and sixty-four children had recovery. Compared to recovery group, sequelae group had more axonal subtypes(62.5% vs 15.63%, p=0.002) and more persistent asymmetry weakness(62.5% vs 4.69%, p=0.000). In six persistent asymmetry GBS, 5(83.33%) had abnormal EEG (electroencephalogram) results, 3(50%) children had mild to marked pleocytosis in CSF and 5(83.33%) had sequelae. Conclusions: In conclusion, asymmetry GBS had two types, namely transient and persistent asymmetry weakness. Asymmetry GBS indicated a more complex condition during disease. Most of persistent asymmetry GBS had clinical or subclinical infectious disease and poor prognosis. Inflammatory in anterior horn cells or nerve root by infectious disease may be the possible function in persistent asymmetry GBS.

Long-term impact on work and private life after Guillain–Barré syndrome

2002 ◽  
Vol 201 (1-2) ◽  
pp. 13-17 ◽  
Author(s):  
Robert A.J.A.M Bernsen ◽  
Aeiko E.J de Jager ◽  
Paul I.M Schmitz ◽  
Frans G.A van der Meché
Keyword(s):  
Private Life ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Long Term Impact

scholarly journals A Case Report of a Patient with Guillain-Barre Syndrome Who Complained of Quadriplegia

2021 ◽  
Vol 42 (5) ◽  
pp. 1009-1019
Author(s):  
Gi-yoon Heo ◽  
Chan Lee ◽  
Im-hak Cho ◽  
Hee-kyung Kang ◽  
Min-hwa Kim ◽  
...  
Keyword(s):  
Muscle Weakness ◽  
Muscle Function ◽  
Hospital Admissions ◽  
Combined Treatment ◽  
Gait Pattern ◽  
Guillain Barre Syndrome ◽  
Poor Prognostic Factor ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Purpose: The aim of this study was to report the improvement of Guillain-Barre syndrome after long-term combination treatment with Korean medicine.Methods: A patient was diagnosed with Guillain-Barre syndrome and treated with herbal medicine, acupuncture, pharmacopuncture, moxibustion, and exercise, including quadruped walking after three hospital admissions. To evaluate muscle strength and weakness, we measured manual muscle function, gait pattern, and the speed of quadruped walking.Results: The patient's muscle weakness in the extremities and gait stance were improved. The speed of quadruped walking was increased.Conclusion: We consider that combined treatment with Korean medicine might be effective for the muscle weakness of Guillain-Barre syndrome with a poor prognostic factor. To verify the effectiveness of this treatment, further research is needed.

Guillain-Barré Syndrome

2019 ◽  
pp. 193-207
Author(s):  
Matthew J. G. Burford ◽  
Richard A. Lewis
Keyword(s):  
Differential Diagnosis ◽  
Immune Therapy ◽  
Treatment Options ◽  
General Pattern ◽  
Clinical Manifestations ◽  
Sudden Onset ◽  
Guillain Barre Syndrome ◽  
Clinical Scenario ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

This chapter begins by outlining the origin of Guillain-Barré syndrome (GBS). It looks at the epidemiology and antecedent events. It also considers clinical manifestations. The classic clinical scenario is one of acute, symmetric, progressive, ascending weakness, and areflexia, with or without sensory symptoms days to weeks after a preceding infection. Next differential diagnosis is examined. The differential diagnosis of GBS is quite broad and includes disorders leading to sudden onset of weakness. The general pattern of clinical involvement and medical history helps to hone the differential. Finally, the chapter looks at management of the syndrome and treatment options for various different groups, such as immune therapy.

Importance of intensive and prolonged rehabilitative treatment on the Guillain-Barrè syndrome long-term outcome: a retrospective study

2019 ◽  
Vol 41 (2) ◽  
pp. 321-327 ◽  
Author(s):  
Valeria Prada ◽  
Federico Massa ◽  
Alexander Salerno ◽  
Davide Fregosi ◽  
Alessandro Beronio ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Guillain Barre Syndrome ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Rehabilitative Treatment ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals The use of standardized order sets to optimize treatment for Guillain-Barre Syndrome: a literature review

2015 ◽  
Vol 42 (S1) ◽  
pp. S35-S35
Author(s):  
V Karnik ◽  
T Roberts ◽  
W Johnston
Keyword(s):  
Treatment Options ◽  
Specific Treatment ◽  
Guillain Barre Syndrome ◽  
Published Data ◽  
Disease States ◽  
Order Sets ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Disease Specific ◽  
Order Set

Background: Standardized order sets are thought to improve patient outcomes in multiple ways. They reduce costs without reducing quality of care, and improve efficiency. In both surgical and medical conditions patients benefit from order sets in various disease states. In Guillain-Barre syndrome (GBS), the use of standardized order sets may be beneficial as there are a defined set of disease-specific diagnostic tests and treatments to be implemented. Here, the primary aim was to search for, and evaluate standardized order sets for GBS, and to provide a basis for development of future pathways. Methods: We used the Cochrane, TRIP, and MEDLINE/PUBMED databases, searching between January 1966 and April 2014. Search terms included: “Guillain-Barre Syndrome” and its synonyms, “(standardized) order set”, “clinical pathway”, “neurology” and “admission bundle.” Results: Despite anecdotal evidence of order sets, no formal data has been published showing benefit after implementation of these sets in GBS or any neurological condition. Conclusions: Although evidence exists for use of standardized order sets in surgical and medical settings, no published data exist in neurology. Given GBS has a defined set of disease-specific and state-specific treatment options, a standardized order set used on admission for GBS patients may prove to be beneficial.

Long-term outcome in children with Guillain-Barré syndrome

2003 ◽  
Vol 142 (3) ◽  
pp. 305-309 ◽  
Author(s):  
Jiri Vajsar ◽  
Darcy Fehlings ◽  
Derek Stephens
Keyword(s):  
Guillain Barre Syndrome ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré
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