scholarly journals Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway

Oncotarget ◽  
2017 ◽  
Vol 8 (33) ◽  
pp. 55384-55393 ◽  
Author(s):  
Leiming Zhang ◽  
Maojing Zhu ◽  
Minmin Li ◽  
Yuan Du ◽  
Sijin Duan ◽  
...  
Keyword(s):  
Signal Pathway ◽  
Ginsenoside Rg1 ◽  
Adjuvant Induced Arthritis ◽  
Ppar Γ

P8 Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ

2017 ◽  
Vol 139 ◽  
pp. 127
Author(s):  
Maojing Zhu ◽  
Minmin Li ◽  
Leiming Zhang ◽  
Yanan Huang ◽  
Yongying Lu ◽  
...  
Keyword(s):  
Ginsenoside Rg1 ◽  
Adjuvant Induced Arthritis ◽  
Ppar Γ

scholarly journals Protective Effect of Ginsenoside Rg1 on Bleomycin-Induced Pulmonary Fibrosis in Rats: Involvement of Caveolin-1 and TGF-β1 Signal Pathway

2016 ◽  
Vol 39 (8) ◽  
pp. 1284-1292 ◽  
Author(s):  
Heqin Zhan ◽  
Feng Huang ◽  
Wenzhuo Ma ◽  
Zhenghang Zhao ◽  
Haifang Zhang ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Protective Effect ◽  
Signal Pathway ◽  
Ginsenoside Rg1 ◽  
Caveolin 1 ◽  
Tgf Β1

Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-γ/Glut4 signal pathway

2020 ◽  
Vol 257 ◽  
pp. 112863 ◽  
Author(s):  
Shuyin Bao ◽  
Yan-Ling Wu ◽  
Xiuzhi Wang ◽  
Shuying Han ◽  
SungBo Cho ◽  
...  
Keyword(s):  
Hepatic Injury ◽  
Signal Pathway ◽  
Ppar Γ ◽  
Type 2 Diabetic

Therapeutic Effect of Penta-acetyl Geniposide on Adjuvant-Induced Arthritis in Rats: Involvement of Inducing Synovial Apoptosis and Inhibiting NF-κB Signal Pathway

Inflammation ◽  
2018 ◽  
Vol 41 (6) ◽  
pp. 2184-2195 ◽  
Author(s):  
Li Cai ◽  
Chun-mei Li ◽  
Wen-jian Tang ◽  
Ming-ming Liu ◽  
Wei-na Chen ◽  
...  
Keyword(s):  
Therapeutic Effect ◽  
Signal Pathway ◽  
Adjuvant Induced Arthritis

scholarly journals Postharvest UV-B Irradiation Stimulated Ginsenoside Rg1 Biosynthesis through Nitric Oxide (NO) and Jasmonic Acid (JA) in Panax quinquefolius Roots

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1462
Author(s):  
Jie Zhou ◽  
Zhi-fang Ran ◽  
Xiao-tong Yang ◽  
Jia Li
Keyword(s):  
Nitric Oxide ◽  
Jasmonic Acid ◽  
Signal Pathway ◽  
Panax Quinquefolius ◽  
Ginsenoside Rg1 ◽  
Drying Process ◽  
Synthesis Inhibitor ◽  
Nos Inhibitors ◽  
Underlying Mechanisms ◽  
Dependent Pathway

The study highlights the influence and signal transduction mechanism of postharvest UV-B on the production of Rg1 in Panax quinquefolius roots during the drying process. The results showed that postharvest UV-B irradiation induced generation of nitric oxide (NO), jasmonic acid (JA), and ginsenoside Rg1 of P. quinquefolius roots. The UV-B-induced increase of Rg1 was suppressed by NO-specific scavenger (cPTIO) and NOS inhibitors (PBITU), JA synthesis inhibitor (SHAM), and JA synthesis inhibitor (PrGall), indicating that NO and JA played essential parts in UV-B-induced Rg1. External NO inhibitors treatment inhibited UV-B-induced accumulation of NO and JA, which suggested that NO was located upstream of the JA signal pathway. NO-caused Rg1 was inhibited by SHAM and PrGall, implying JA participated in transmitting signal NO to Rg1 accumulation. In other words, NO mediated the postharvest UV-B-induced Rg1 accumulation by the JA-dependent pathway in P. quinquefolius roots during the drying process, which helps us understand the underlying mechanisms involved in UV-B-induced Rg1 production and provides information helpful for P. quinquefolius production.

Sign in / Sign up

Export Citation Format

Share Document