γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

Kodappully Sivaraman Siveen; Kwang Seok Ahn; Tina H. Ong; Muthu K. Shanmugam; Feng Li; Wei Ney Yap; Alan Prem Kumar; Chee Wai Fong; Vinay Tergaonkar; Kam M Hui; Gautam Sethi

doi:10.18632/oncotarget.1876

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

Oncotarget ◽

10.18632/oncotarget.1876 ◽

2014 ◽

Vol 5 (7) ◽

pp. 1897-1911 ◽

Cited By ~ 90

Author(s):

Kodappully Sivaraman Siveen ◽

Kwang Seok Ahn ◽

Tina H. Ong ◽

Muthu K. Shanmugam ◽

Feng Li ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Mtor Pathway ◽

Human Hepatocellular Carcinoma ◽

Orthotopic Mouse Model ◽

Dependent Growth

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The Cyclooxygenase-2 Inhibitor Celecoxib Attenuates Hepatocellular Carcinoma Growth and c-Met Expression in an Orthotopic Mouse Model

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504011x12935427587803 ◽

2011 ◽

Vol 19 (3) ◽

pp. 131-139 ◽

Cited By ~ 9

Author(s):

Jibin Yin ◽

Bingrong Liu ◽

Baoxin Li ◽

Zhaojun Liu ◽

Xinyu Xie ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Cyclooxygenase 2 ◽

Orthotopic Mouse Model

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The mTOR pathway is associated with the poor prognosis of human hepatocellular carcinoma

Medical Oncology ◽

10.1007/s12032-009-9201-4 ◽

2009 ◽

Vol 27 (2) ◽

pp. 255-261 ◽

Cited By ~ 126

Author(s):

Ledu Zhou ◽

Yun Huang ◽

Jingdong Li ◽

Zhiming Wang

Keyword(s):

Hepatocellular Carcinoma ◽

Poor Prognosis ◽

Mtor Pathway ◽

Human Hepatocellular Carcinoma ◽

The Poor

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Targeting vascular endothelial growth factor with the monoclonal antibody bevacizumab inhibits human hepatocellular carcinoma cells growing in an orthotopic mouse model

Liver International ◽

10.1111/j.1478-3231.2008.01762.x ◽

2009 ◽

Vol 29 (2) ◽

pp. 284-290 ◽

Cited By ~ 16

Author(s):

Richard S. Finn ◽

Greg Bentley ◽

Carolyn D. Britten ◽

Rafael Amado ◽

Ronald W. Busuttil

Keyword(s):

Hepatocellular Carcinoma ◽

Monoclonal Antibody ◽

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Mouse Model ◽

Carcinoma Cells ◽

Vascular Endothelial ◽

Orthotopic Mouse Model ◽

Endothelial Growth Factor ◽

Human Hepatocellular Carcinoma Cells

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Osthole attenuates angiogenesis in an orthotopic mouse model of hepatocellular carcinoma via the downregulation of nuclear factor‑κB and vascular endothelial growth factor

Oncology Letters ◽

10.3892/ol.2018.9213 ◽

2018 ◽

Cited By ~ 4

Author(s):

Fei Yao ◽

Lurong Zhang ◽

Guorong Jiang ◽

Min Liu ◽

Guoqiang Liang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Mouse Model ◽

Nuclear Factor Κb ◽

Vascular Endothelial ◽

Nuclear Factor ◽

Orthotopic Mouse Model ◽

Endothelial Growth Factor

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Abstract 2975: Transgenic mouse model of Twist1-induced metastasis reveals genes highly prognostic for human hepatocellular carcinoma

10.1158/1538-7445.am2012-2975 ◽

2012 ◽

Author(s):

David I. Bellovin ◽

Phuoc T. Tran ◽

Stacey J. Adam ◽

Andrew J. Gentles ◽

Xin W. Wang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Human Hepatocellular Carcinoma

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Activated Human Hepatic Stellate Cells Promote Growth of Human Hepatocellular Carcinoma in a Subcutaneous Xenograft Nude Mouse Model

Cell Biochemistry and Biophysics ◽

10.1007/s12013-014-9918-3 ◽

2014 ◽

Vol 70 (1) ◽

pp. 337-347 ◽

Cited By ~ 10

Author(s):

Zhi-min Geng ◽

Qing-hua Li ◽

Wen-zhi Li ◽

Jian-bao Zheng ◽

Vijay Shah

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Nude Mouse ◽

Hepatic Stellate Cells ◽

Stellate Cells ◽

Human Hepatocellular Carcinoma ◽

Nude Mouse Model ◽

Subcutaneous Xenograft

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Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

Molecular Cancer ◽

10.1186/1476-4598-13-253 ◽

2014 ◽

Vol 13 (1) ◽

pp. 253 ◽

Cited By ~ 41

Author(s):

Yanqiong Zhang ◽

Xiaodong Guo ◽

Lu Xiong ◽

Lingxiang Yu ◽

Zhiwei Li ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Protein Interaction ◽

Protein Interaction Network ◽

Interaction Network ◽

Comprehensive Analysis ◽

Mtor Pathway ◽

Human Hepatocellular Carcinoma

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Metformin decreases IL-22 secretion to suppress tumor growth in an orthotopic mouse model of hepatocellular carcinoma

International Journal of Cancer ◽

10.1002/ijc.29305 ◽

2014 ◽

Vol 136 (11) ◽

pp. 2556-2565 ◽

Cited By ~ 40

Author(s):

Dong Zhao ◽

Xi-Dai Long ◽

Tian-Fei Lu ◽

Tao Wang ◽

Wei-Wei Zhang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Tumor Growth ◽

Orthotopic Mouse Model

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Human Hepatocellular Carcinoma in a Mouse Model: Assessment of Tumor Response to Percutaneous Ablation by Using Glyceraldehyde-3-Phosphate Dehydrogenase Antagonists

Radiology ◽

10.1148/radiol.11111569 ◽

2012 ◽

Vol 262 (3) ◽

pp. 834-845 ◽

Cited By ~ 34

Author(s):

Shanmugasundaram Ganapathy-Kanniappan ◽

Rani Kunjithapatham ◽

Michael S. Torbenson ◽

Pramod P. Rao ◽

Kathryn A. Carson ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Tumor Response ◽

Human Hepatocellular Carcinoma ◽

Percutaneous Ablation ◽

Model Assessment

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Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model

Hepatology ◽

10.1002/hep.24075 ◽

2011 ◽

Vol 53 (2) ◽

pp. 483-492 ◽

Cited By ~ 67

Author(s):

Yu-Xiong Feng ◽

Tao Wang ◽

Yue-Zhen Deng ◽

Pengyuan Yang ◽

Jing-Jing Li ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mouse Model ◽

Orthotopic Mouse Model ◽

Postsurgical Recurrence

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