scholarly journals Alpha-glucosidase inhibitors and risk of cancer in patients with diabetes mellitus: a systematic review and meta-analysis

Oncotarget ◽  
2017 ◽  
Vol 8 (46) ◽  
pp. 81027-81039 ◽  
Author(s):  
Yiming Zhao ◽  
Yongjian Wang ◽  
Hanyu Lou ◽  
Lizhen Shan
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Meta Analysis ◽  
Glucosidase Inhibitors ◽  
Patients With Diabetes ◽  
Risk Of Cancer ◽  
Alpha Glucosidase

Significantly Increased Risk of Cancer in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis

2011 ◽  
Vol 17 (4) ◽  
pp. 616-628 ◽  
Author(s):  
Hiroshi Noto ◽  
Tetsuro Tsujimoto ◽  
Takehiko Sasazuki ◽  
Mitsuhiko Noda
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Meta Analysis ◽  
Increased Risk ◽  
Patients With Diabetes ◽  
Risk Of Cancer

scholarly journals Catheter ablation of atrial fibrillation in patients with diabetes mellitus: a systematic review and meta-analysis

EP Europace ◽  
2015 ◽  
Vol 17 (10) ◽  
pp. 1518-1525 ◽  
Author(s):  
Matteo Anselmino ◽  
Mario Matta ◽  
Fabrizio D'ascenzo ◽  
Carlo Pappone ◽  
Vincenzo Santinelli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Atrial Fibrillation ◽  
Systematic Review ◽  
Catheter Ablation ◽  
Meta Analysis ◽  
Patients With Diabetes

Collective empowerment strategies for patients with Diabetes Mellitus: A systematic review and meta-analysis

2017 ◽  
Vol 11 (2) ◽  
pp. 201-211 ◽  
Author(s):  
Nayara Ragi Baldoni ◽  
Jéssica Azevedo Aquino ◽  
Cristina Sanches-Giraud ◽  
Cláudia Di Lorenzo Oliveira ◽  
Roberta Carvalho de Figueiredo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Meta Analysis ◽  
Patients With Diabetes ◽  
Collective Empowerment

scholarly journals Three‐Dimensional Global Left Ventricular Myocardial Strain Reduced in All Directions in Subclinical Diabetic Cardiomyopathy: A Systematic Review and Meta‐Analysis

2021 ◽  
Author(s):  
Seyed‐Mohammad Ghoreyshi‐Hefzabad ◽  
Prajith Jeyaprakash ◽  
Alpa Gupta ◽  
Ha Q. Vo ◽  
Faraz Pathan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Longitudinal Strain ◽  
Circumferential Strain ◽  
Meta Analysis ◽  
Global Longitudinal Strain ◽  
Three Dimensional ◽  
Significant Heterogeneity ◽  
Global Circumferential Strain ◽  
Patients With Diabetes

Background Three‐dimensional (3D) speckle tracking echocardiography can identify subclinical diabetic cardiomyopathy without geometric assumption and loss of speckle from out‐of‐plane motions. There is, however, significant heterogeneity among the previous reports. We performed a systematic review and meta‐analysis to compare 3D strain values between adults with asymptomatic, subclinical diabetes mellitus (ie, patients with diabetes mellitus without known clinical manifestations of cardiac disease) and healthy controls. Methods and Results After systematic review of 5 databases, 12 valid studies (544 patients with diabetes mellitus and 489 controls) were eligible for meta‐analysis. Pooled means and mean difference (MD) using a random‐effects model for 3D global longitudinal, circumferential, radial, and area strain were calculated. Patients with diabetes mellitus had an overall 2.31 percentage points lower 3D global longitudinal strain than healthy subjects (16.6%, 95% CI, 15.7–17.6 versus 19.0; 95% CI, 18.2–19.7; MD, −2.31, 95% CI, −2.72 to −2.03). Similarly, 3D global circumferential strain (18.9%; 95% CI, 17.5–20.3 versus 20.5; 95% CI, 18.9–22.1; MD, −1.50; 95% CI, −2.09 to −0.91); 3D global radial strain (44.6%; 95% CI, 40.2–49.1 versus 48.2; 95% CI, 44.7–51.8; MD, −3.47; 95% CI, −4.98 to −1.97), and 3D global area strain (30.5%; 95% CI, 29.2–31.8 versus 32.4; 95% CI, 30.5–34.3; MD, −1.76; 95% CI, −2.74 to −0.78) were also lower in patients with diabetes mellitus. Significant heterogeneity was noted between studies for all strain directions (inconsistency factor [I 2 ], 37%–78%). Meta‐regression in subgroup analysis of studies using the most popular vendor found higher prevalence of hypertension as a significant contributor to worse 3D global longitudinal strain. Higher hemoglobulin A 1c was the most significant contributor to worse 3D global circumferential strain in patients with diabetes mellitus. Conclusions Three‐dimensional myocardial strain was reduced in all directions in asymptomatic diabetic patients. Hypertension and hemoglobin A 1c were associated with worse 3D global longitudinal strain and 3D global circumferential strain, respectively. Registration URL: https://www.crd.york.ac.uk/prospero ; unique identifier: CRD42020197825.

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