scholarly journals p-Akt as a potential poor prognostic factor for gastric cancer: a systematic review and meta-analysis

Oncotarget ◽  
2017 ◽  
Vol 8 (35) ◽  
pp. 59878-59888 ◽  
Author(s):  
Fang Cao ◽  
Cong Zhang ◽  
Wei Han ◽  
Xiao-Jiao Gao ◽  
Jun Ma ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Prognostic Factor ◽  
Meta Analysis ◽  
Poor Prognostic Factor

scholarly journals Tumour deposits are a significant prognostic factor in gastric cancer – a systematic review and meta‐analysis

2019 ◽  
Vol 74 (6) ◽  
pp. 809-816 ◽  
Author(s):  
Cristina Graham Martínez ◽  
Nikki Knijn ◽  
Marcel Verheij ◽  
Iris D Nagtegaal ◽  
Rachel S Post
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Prognostic Factor ◽  
Meta Analysis ◽  
Significant Prognostic Factor

scholarly journals TMPRSS4 as an emerging potential poor prognostic factor for solid tumors: A systematic review and meta-analysis

Oncotarget ◽  
2016 ◽  
Vol 7 (46) ◽  
pp. 76327-76336 ◽  
Author(s):  
Ping Zeng ◽  
Peng Zhang ◽  
Li-Na Zhou ◽  
Min Tang ◽  
Yi-Xin Shen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factor ◽  
Solid Tumors ◽  
Meta Analysis ◽  
Poor Prognostic Factor

scholarly journals The clinicopathological features and prognostic value of lymphovascular invasion in patients with upper tract urinary carcinoma after radical nephroureterectomy:  an updated systematic review and meta-analysis.

2019 ◽  
Author(s):  
Lijin Zhang ◽  
Bin Wu ◽  
Zhenlei Zha ◽  
Hu Zhao ◽  
Jun Yuan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factor ◽  
Prognostic Value ◽  
Lymphovascular Invasion ◽  
Meta Analysis ◽  
Clinicopathological Features ◽  
Current Evidence ◽  
Radical Nephroureterectomy ◽  
Poor Prognostic Factor ◽  
Upper Tract

Abstract Background and Purpose: Although the prognostic value of lymphovascular invasion (LVI) for upper tract urinary carcinoma (UTUC) have been described. There is lack of consensus regarding the prognostic factor of LVI in UTUC. The aim of present study was to evaluate the current evidence regarding the contemporary role of LVI through systematic review and meta-analysis according to the updated literatures. Materials and Methods: In the light of Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, a systematic search of Web of Science, PubMed and EMBASE was performed for all reports published until July 2019 that included detailed results on the predictors of LVI. Results: Our meta-analysis included thirty one eligible studies containing 14,653 UTUC patients (81-1,363 per study). According to our final results, there was a significant correlation of LVI with worse cancer-specific survival (CSS) (HR=1.62, 95 % CI: 1.49-1.76, p < 0.001), overall survival (OS) (HR=1.55, 95 % CI: 1.41-1.71, p < 0.001), recurrence-free survival (RFS) (HR=1.46, 95 % CI: 1.32-1.61, p < 0.001), cancer-specific mortality (CSM) (HR=1.25, 95 % CI: 1.00-1.56, p = 0.047) and recurrence(HR=1.23, 95 % CI: 1.03-1.48, p = 0.026). In addition, LVI was also correlated with advanced TNM stage (III/IV vs. I/II: OR = 7.63, 95% CI: 5.60–10.39, p < 0.001), higher tumor grade (3 vs. 1/2: OR = 5.61, 95% CI: 3.71–8.48, p < 0.001), lymph node metastasis (yes vs. no: OR = 4.95, 95% CI: 3.66–6.71, p < 0.001), carcinoma in situ (yes vs. no: OR = 1.92, 95% CI: 1.36–2.70, p < 0.001) and positive surgical margin (yes vs. no: OR = 4.38, 95% CI: 2.71–7.07, p < 0.001), but not related to gender (male vs. female: OR = 0.98, 95% CI: 0.80–1.19, p = 0.825) and multifocality (multifocal vs. unifocal: OR = 1.10, 95% CI: 0.82–1.47, p = 0.539). The funnel plot test indicated that no significant publication bias in the meta-analysis. Conclusions: This study demonstrated that LVI was associated with more aggressive clinicopathological features and could serve as a poor prognostic factor for patient with UTUC after radical nephroureterectomy.

scholarly journals Tetraspanin CD151 as an emerging potential poor prognostic factor across solid tumors: a systematic review and meta-analysis

Oncotarget ◽  
2016 ◽  
Vol 8 (3) ◽  
pp. 5592-5602 ◽  
Author(s):  
Ping Zeng ◽  
Yin-Hua Wang ◽  
Meng Si ◽  
Jin-Hua Gu ◽  
Ping Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factor ◽  
Solid Tumors ◽  
Meta Analysis ◽  
Poor Prognostic Factor
Sign in / Sign up

Export Citation Format

Share Document