PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer

Liyan Chen; Tiefeng Jin; Kun Zhu; Yingshi Piao; Taihao Quan; Chunji Quan; Zhenhua Lin

doi:10.18632/oncotarget.14442

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer

Oncotarget ◽

10.18632/oncotarget.14442 ◽

2017 ◽

Vol 8 (7) ◽

pp. 11937-11949 ◽

Cited By ~ 15

Author(s):

Liyan Chen ◽

Tiefeng Jin ◽

Kun Zhu ◽

Yingshi Piao ◽

Taihao Quan ◽

...

Keyword(s):

Breast Cancer ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Dual Inhibitor ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Anti Tumor Activity

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The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells

Oncology Reports ◽

10.3892/or.2011.1488 ◽

2011 ◽

Cited By ~ 4

Author(s):

Bridgette Collins-Burow

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Trichostatin A ◽

Expression Profiles ◽

Microrna Expression ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor α-negative breast cancer cells to tamoxifen

Oncogene ◽

10.1038/sj.onc.1207315 ◽

2003 ◽

Vol 23 (9) ◽

pp. 1724-1736 ◽

Cited By ~ 102

Author(s):

Eun Ryoung Jang ◽

Soo-Jeong Lim ◽

Eun Sook Lee ◽

Gajin Jeong ◽

Tae-You Kim ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Trichostatin A ◽

Estrogen Receptor Α ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen

The Women s Oncology Review ◽

10.3109/14733400412331313133 ◽

2004 ◽

Vol 4 (3) ◽

pp. 187-189

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Estrogen Receptor Alpha ◽

Trichostatin A ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen

The Women s Oncology Review ◽

10.1080/14733400412331313133 ◽

2004 ◽

Vol 4 (3) ◽

pp. 187-189

Author(s):

Not Available Not Available

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Breast Cancer Cells ◽

Estrogen Receptor Alpha ◽

Trichostatin A ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cells

Molecular Medicine Reports ◽

10.3892/mmr.2018.8446 ◽

2018 ◽

Author(s):

Liang Gao ◽

Xin Sun ◽

Qi Zhang ◽

Xiaochen Chen ◽

Tongwei Zhao ◽

...

Keyword(s):

Epithelial Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Breast Epithelial Cells ◽

Autophagy Inhibitor ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Breast Epithelial ◽

Anti Tumor Activity

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Effect of histone deacetylase inhibitor trichostatin A (TSA) on the microtubular system ofTetrahymena

Acta Biologica Hungarica ◽

10.1556/abiol.58.2007.4.5 ◽

2007 ◽

Vol 58 (4) ◽

pp. 381-387

Author(s):

P. Kovács ◽

Éva Pállinger ◽

G. Csaba

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Microtubular System

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Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2005.02.147 ◽

2005 ◽

Vol 330 (1) ◽

pp. 204-209 ◽

Cited By ~ 18

Author(s):

Zhong-Ping Lu ◽

Zhong-Liang Ju ◽

Guang-Yin Shi ◽

Jing-Wu Zhang ◽

Jian Sun

Keyword(s):

Histone Deacetylase ◽

Gene Transcription ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Autoantibody Production ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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THE CIRCADIAN EXPRESSION OF c-MYC IS MODULATED BY THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A IN SYNCHRONIZED MURINE NEUROBLASTOMA CELLS

Chronobiology International ◽

10.3109/07420521003786800 ◽

2010 ◽

Vol 27 (4) ◽

pp. 722-741 ◽

Cited By ~ 14

Author(s):

Anastasia Repouskou ◽

Thomae G. Sourlingas ◽

Kalliope E. Sekeri-Pataryas ◽

Anastasia Prombona

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Neuroblastoma Cells ◽

Murine Neuroblastoma ◽

Circadian Expression ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus

Oncotarget ◽

10.18632/oncotarget.25242 ◽

2018 ◽

Vol 9 (41) ◽

pp. 26328-26341 ◽

Cited By ~ 4

Author(s):

Sarah L. Hulin-Curtis ◽

James A. Davies ◽

Rachel Jones ◽

Emma Hudson ◽

Louise Hanna ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Oncolytic Adenovirus ◽

Ovarian Cancer Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin

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Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells

APOPTOSIS ◽

10.1023/b:appt.0000038037.68908.6e ◽

2004 ◽

Vol 9 (5) ◽

pp. 583-589 ◽

Cited By ~ 40

Author(s):

M. S. Roh ◽

C. W. Kim ◽

B. S. Park ◽

G. C. Kim ◽

J. H. Jeong ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Osteosarcoma Cells ◽

Human Osteosarcoma ◽

Human Osteosarcoma Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Induced Apoptosis

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