scholarly journals Dosimetric evaluation of the skin-sparing effects of 3-dimensional conformal radiotherapy and intensity-modulated radiotherapy for left breast cancer

Oncotarget ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 3059-3063 ◽  
Author(s):  
In Young Jo ◽  
Shin-Wook Kim ◽  
Seok Hyun Son
Keyword(s):  
Breast Cancer ◽  
Intensity Modulated Radiotherapy ◽  
Conformal Radiotherapy ◽  
Left Breast ◽  
3 Dimensional ◽  
Intensity Modulated

Intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy during deep inspiratory breath hold for left-sided whole-breast irradiation: a comparative analysis

2015 ◽  
Vol 15 (1) ◽  
pp. 99-106
Author(s):  
D. M. Trifiletti ◽  
K. Wijesooriya ◽  
G. Moyer ◽  
D. Lain ◽  
C. Geesey ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Organs At Risk ◽  
Three Dimensional ◽  
Intensity Modulated Radiotherapy ◽  
Conformal Radiotherapy ◽  
Left Breast ◽  
Breath Hold ◽  
Breast Irradiation ◽  
Intensity Modulated ◽  
Three Dimensional Conformal Radiotherapy

AbstractAimDeep inspiratory breath hold (DIBH) during left-breast irradiation helps to minimise cardiac irradiation by physically separating the heart from the left breast. The dose to organs-at-risk in intensity-modulated radiotherapy (IMRT) and opposed tangent three-dimensional conformal radiotherapy (3DCRT) during DIBH in patients with left-sided breast cancer was compared.Materials and methodsA total of 20 consecutive patients with left-sided breast cancer had a computed tomography scan utilising DIBH. Mean volumes of the heart, left anterior descending coronary artery, total lung and right breast receiving 5–95% of the prescription dose were calculated.ResultsTarget volume homogeneity was improved with IMRT and average mean dose to target was higher for 3DCRT (51·03 Gy) compared with IMRT (50·47 Gy, p<0·01). The average mean dose to the heart was lower with 3DCRT (87 versus 77 cGy, p<0·01). The average mean dose to the contralateral breast was also lower with 3DCRT (19 versus 17 cGy, p<0·01). Less monitor units (MUs) were required with 3DCRT with an average difference of 225 MU/fraction (p<0·01).FindingsUnder DIBH, absolute differences between 3DCRT and IMRT were minimal. 3DCRT under DIBH provided excellent dosimetric results in most patients with left-sided breast cancer without the need for IMRT.

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