scholarly journals Metastatic lymph node ratio can further stratify risk for mortality in medullary thyroid cancer patients: A population-based analysis

Oncotarget ◽  
2016 ◽  
Vol 7 (40) ◽  
pp. 65937-65945 ◽  
Author(s):  
Ning Qu ◽  
Rong-liang Shi ◽  
Zhong-wu Lu ◽  
Tian Liao ◽  
Duo Wen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Medullary Thyroid Cancer ◽  
Lymph Node Ratio ◽  
Metastatic Lymph Node ◽  
Population Based ◽  
Medullary Thyroid ◽  
Metastatic Lymph ◽  
Node Ratio

Prognostic Significance of the Metastatic Lymph Node Ratio in Gastric Cancer Patients

2009 ◽  
Vol 33 (11) ◽  
pp. 2378-2382 ◽  
Author(s):  
Naoto Fukuda ◽  
Yasuyuki Sugiyama ◽  
Akira Midorikawa ◽  
Hiroyuki Mushiake
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Lymph Node Ratio ◽  
Metastatic Lymph Node ◽  
Prognostic Significance ◽  
Metastatic Lymph ◽  
Node Ratio ◽  
Gastric Cancer Patients

Can metastatic lymph node ratio (LNR) predict survival in oral cavity cancer patients?

2013 ◽  
Vol 108 (4) ◽  
pp. 256-263 ◽  
Author(s):  
Suhail I. Sayed ◽  
Shilpi Sharma ◽  
Pawan Rane ◽  
Sagar Vaishampayan ◽  
Sanjay Talole ◽  
...  
Keyword(s):  
Lymph Node ◽  
Oral Cavity ◽  
Cancer Patients ◽  
Lymph Node Ratio ◽  
Oral Cavity Cancer ◽  
Metastatic Lymph Node ◽  
Metastatic Lymph ◽  
Node Ratio

scholarly journals Metastatic Lymph Node Ratio for Predicting Recurrence in Medullary Thyroid Cancer

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5842
Author(s):  
Jinyoung Kim ◽  
Jun Park ◽  
Hyunju Park ◽  
Min Sun Choi ◽  
Hye Won Jang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Medullary Thyroid Cancer ◽  
Lymph Node Ratio ◽  
Serum Calcitonin ◽  
Free Survival ◽  
Medullary Thyroid ◽  
Node Ratio ◽  
Postoperative Serum

The lymph node ratio (LNR) has been investigated as a prognostic factor in many different types of cancers, including differentiated thyroid cancer; however, reports regarding medullary thyroid cancer (MTC) are limited. Therefore, this study aims to evaluate LNR as a risk factor for structural recurrence in patients with MTC. Medical records of patients treated for MTC in a single tertiary center between 1995 and 2017 were retrospectively reviewed. LNR is defined as the number of metastatic lymph nodes or lymph node metastases (LNM) divided by the number of retrieved lymph nodes or lymph node yield (LNY). In the survival analysis, recurrence-free survival was defined as the time from the date of total thyroidectomy to recurrence or last follow-up. To identify risk factors influencing structural recurrence, univariable and multivariable Cox proportional hazard models were used. A total of 132 patients were enrolled. The mean age of study participants was 49.7 years, and 86 patients (65%) were women. Structural recurrence was identified in 39 patients at the end of the study period, and the median follow-up period was 8.7 years. In univariable analyses, gross extra thyroidal extension, N stage, postoperative serum calcitonin and carcinoembryonic antigen (CEA) levels, and LNR were significant (p < 0.05) predictors of structural recurrence. In multivariable analysis, postoperative serum calcitonin, postoperative serum CEA, and LNR were identified as a predictor of disease-free survival (p < 0.05). LNR can potentially predict structural recurrence as a quantitative evaluation tool for lymph node metastasis in patients with MTC.

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