scholarly journals Nomograms incorporated serum direct bilirubin level for predicting prognosis in stages II and III colorectal cancer after radical resection

Oncotarget ◽  
2016 ◽  
Vol 8 (41) ◽  
pp. 71138-71146 ◽  
Author(s):  
Qunfeng Zhang ◽  
Xiaowei Ma ◽  
Qunhuan Xu ◽  
Juanxiu Qin ◽  
Yanhua Wang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Bilirubin Level ◽  
Radical Resection ◽  
Direct Bilirubin ◽  
Direct Bilirubin Level

Investigating Jaundice in the Newborn

2007 ◽  
Vol 26 (5) ◽  
pp. 327-333 ◽  
Author(s):  
Jodi Beachy
Keyword(s):  
Preterm Infants ◽  
Bilirubin Level ◽  
Neonatal Period ◽  
Full Term ◽  
Direct Bilirubin ◽  
Unconjugated Bilirubin ◽  
Newborn Period ◽  
Physiologic Response ◽  
Direct Bilirubin Level ◽  
Conjugated Bilirubin

JAUNDICE IS OFTEN SEEN IN the neonatal period, with 60 percent of full-term and 80 percent of preterm infants having visible jaundice.1 Jaundice is a sign of hyperbilirubinemia, which, in the newborn period, is usually due to an elevated indirect or unconjugated bilirubin level, and may result from an exaggerated physiologic response or be pathologic in nature. Hyperibilirubinemia due to an elevated direct or conjugated bilirubin is less common. Although an elevated direct bilirubin level can be transient, it is often related to some pathology.

scholarly journals Association of direct bilirubin level with postoperative outcome in critically ill postoperative patients

2018 ◽  
Vol 71 (1) ◽  
pp. 30
Author(s):  
Masaharu Nagae ◽  
Moritoki Egi ◽  
Kenta Kubota ◽  
Shohei Makino ◽  
Satoshi Mizobuchi
Keyword(s):  
Critically Ill ◽  
Bilirubin Level ◽  
Postoperative Outcome ◽  
Direct Bilirubin ◽  
Direct Bilirubin Level

scholarly journals Oncological evaluation in the perioperative period using cfDNA with BRAF V600E mutation in patients with colorectal cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Keita Tanaka ◽  
Yoichiro Yoshida ◽  
Teppei Yamada ◽  
Takaomi Hayashi ◽  
Hideki Shimaoka ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Perioperative Period ◽  
Radical Resection ◽  
Braf V600e ◽  
Tumor Diameter ◽  
Prognostic Information ◽  
A Prospective Study ◽  
Digital Polymerase Chain Reaction ◽  
The Relationship

AbstractThe detection of circulating cell-free DNA (cfDNA) by liquid biopsy is reported to provide prognostic information in colorectal cancer (CRC). Although the frequency of BRAF V600E mutation in CRC is less than 10%, it is associated with poor responses to conventional chemotherapy. We conducted a prospective study to investigate the relationship between the perioperative mutant allele frequency (MAF) of BRAF V600E and tumor recurrence, and to evaluate the possibility of early detection of recurrence. Among 362 patients who underwent radical resection, cfDNA was extracted from the perioperative blood of 11 CRC patients with BRAF V600E mutation and analyzed using the digital polymerase chain reaction (dPCR) system. The median follow-up time was 22 months, and there were four cases of recurrence. Although there was no correlation between recurrence and the perioperative MAF of BRAF V600E, tumor diameter was correlated with the MAF (p = 0.024), and the MAF increased with time in two patients from whom additional samples were obtained prior to recurrence. In this study, we identified a correlation between the pathological tumor diameter and the MAF, but it was difficult to predict recurrence by measuring cfDNA with BRAF V600E mutation in the perioperative period of radical resection of CRC.

Prognostic Impact of Hypochloremia in Patients With Stage I to III Colorectal Cancer After Radical Resection

2018 ◽  
Vol 61 (11) ◽  
pp. 1273-1280
Author(s):  
Qingguo Li ◽  
Weixing Dai ◽  
Huixun Jia ◽  
Yaqi Li ◽  
Ye Xu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Radical Resection ◽  
Stage I ◽  
Prognostic Impact
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