scholarly journals MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients

Oncotarget ◽  
2016 ◽  
Vol 8 (31) ◽  
pp. 50608-50617 ◽  
Author(s):  
Camila Maria da Silva Martinelli ◽  
André van Helvoort Lengert ◽  
Flavio Mavignier Cárcano ◽  
Eduardo Caetano Albino Silva ◽  
Mariana Brait ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Promoter Methylation ◽  
Poor Prognosis ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Tumor Patients ◽  
Testicular Germ Cell

High Endogenous DNA Damage Levels Predict Hematological Toxicity in Testicular Germ Cell Tumor Patients Treated With First-Line Chemotherapy

2019 ◽  
Vol 17 (5) ◽  
pp. e1020-e1025
Author(s):  
Nikola Hapakova ◽  
Zuzana Sestakova ◽  
Andrea Holickova ◽  
Lenka Hurbanova ◽  
Vera Miskovska ◽  
...  
Keyword(s):  
Dna Damage ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Hematological Toxicity ◽  
First Line ◽  
Tumor Patients ◽  
Testicular Germ Cell ◽  
Line Chemotherapy

scholarly journals Antioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomy

2017 ◽  
Vol 43 (4) ◽  
pp. 644-651 ◽  
Author(s):  
Camila Sposito ◽  
Mariana Camargo ◽  
Danielle Spinola Tibaldi ◽  
Valéria Barradas ◽  
Agnaldo Pereira Cedenho ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Germ Cell ◽  
Antioxidant Enzyme ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Tumor Patients ◽  
Testicular Germ Cell ◽  
Lipid Peroxidation Products ◽  
Enzyme Profile

A cytokine and angiogenic factor (CAF) analysis in plasma in testicular germ cell tumor patients (TGCTs).

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e15552-e15552 ◽  
Author(s):  
Michal Chovanec ◽  
Michal Mego ◽  
Dana Cholujova ◽  
Paulina Gronesova ◽  
Vera Miskovska ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Angiogenic Factor ◽  
Tumor Patients ◽  
Testicular Germ Cell

scholarly journals Recent malignant testicular tumor trend in Japan, a country with an aging population: a large-scale study of 2012–2015 hospital-based cancer registry data

2020 ◽  
Vol 50 (10) ◽  
pp. 1201-1208
Author(s):  
Kosuke Kojo ◽  
Koji Kawai ◽  
Takashi Kawahara ◽  
Tomokazu Kimura ◽  
Shuya Kandori ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Cell Lymphoma ◽  
Testicular Germ Cell Tumor ◽  
B Cell Lymphoma ◽  
Cell Tumor ◽  
Tumor Patients ◽  
Testicular Germ Cell ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Abstract Objective Japan’s national database of hospital-based cancer registries is estimated to cover ~67% of all new cancer cases. Using this database, we analyzed the characteristics of the recently diagnosed testicular malignancy. Methods We obtained data for 6510 adult testicular malignancy patients diagnosed in 2012–2015. The distributions of patient ages, histological diagnoses and testicular germ cell tumor hospital care volumes were determined. Results The most common histology was seminoma (60.3% of all testicular malignancies), followed by non-seminoma (24.1%) and diffuse large B-cell lymphoma (13.1%). The median and mean ages of the testicular germ cell tumor patients were high at 38 and 39.8 years, respectively. The age distribution peaked at 30–40 years, followed by 40–50 years. Approximately 18% of testicular germ cell tumor patients were ≥50 years. The ages of the diffuse large B-cell lymphoma patients peaked at 70–80 years (mean 67.7 years). When the analysis was limited to the testicular germ cell tumor patients who received first-course cancer treatment at the participating hospitals, the number of high-volume hospitals with ≥20 testicular germ cell tumor care volume was limited to 61 (10.0% of the 605 hospitals that treated ≥1 testicular germ cell tumor patient). However, when the patients who changed hospitals during treatment or relapsed after treatment completion were analyzed together, the number of high-volume hospitals increased to 104 (17.0% of 612 hospitals). Conclusion The testicular germ cell tumor patients’ mean age was nearly 40 years. The proportions of older testicular germ cell tumor patients and diffuse large B-cell lymphoma patients were higher than previously thought. The reasons for this trend are unknown, but it is important to address the trend identified herein in a country with a super-aging population.

scholarly journals Is gynecomastia related to the disease characteristics and prognosis in testicular germ cell tumor patients?

2019 ◽  
Vol 25 (3) ◽  
pp. 189-194 ◽  
Author(s):  
Ahmet Veysel Polat ◽  
◽  
Mesut Ozturk ◽  
Ilkay Camlidag ◽  
Behic Akyuz ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Tumor Patients ◽  
Testicular Germ Cell ◽  
Disease Characteristics

scholarly journals Prognostic value of serum carbonic anhydrase IX in testicular germ cell tumor patients

2016 ◽  
Vol 12 (4) ◽  
pp. 2590-2598 ◽  
Author(s):  
Katarina Kalavska ◽  
Michal Chovanec ◽  
Miriam Zatovicova ◽  
Martina Takacova ◽  
Paulina Gronesova ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Prognostic Value ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Carbonic Anhydrase Ix ◽  
Tumor Patients ◽  
Testicular Germ Cell
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