Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

Yvonne Möller; Markus Morkel; Jens Schmid; Sven Beyes; Janina Hendrick; Michaela Strotbek; Pamela Riemer; Simone Schmid; Lisa C. Schmitt; Roland Kontermann; Thomas Mürdter; Matthias Schwab; Christine Sers; Monilola A. Olayioye

doi:10.18632/oncotarget.10658

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

Oncotarget ◽

10.18632/oncotarget.10658 ◽

2016 ◽

Vol 7 (33) ◽

pp. 53526-53539 ◽

Cited By ~ 4

Author(s):

Yvonne Möller ◽

Markus Morkel ◽

Jens Schmid ◽

Sven Beyes ◽

Janina Hendrick ◽

...

Keyword(s):

Oncogenic Ras ◽

Erbb3 Signaling

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Faculty Opinions recommendation of Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1006218.77810 ◽

2002 ◽

Author(s):

Angel Nebreda

Keyword(s):

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Premature Senescence ◽

Extracellular Signal Regulated Kinase ◽

Oncogenic Ras ◽

Extracellular Signal ◽

Mitogen Activated Protein ◽

Sequential Activation

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Faculty Opinions recommendation of NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1012154.185078 ◽

2003 ◽

Author(s):

Jean Schwarzbauer

Keyword(s):

Oncogenic Ras ◽

Nf Kappab

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Faculty Opinions recommendation of Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029136.346434 ◽

2005 ◽

Author(s):

Dafna Bar-Sagi

Keyword(s):

Akt Pathway ◽

Ras Signaling ◽

Oncogenic Ras ◽

Tumor Maintenance

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Faculty Opinions recommendation of Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088398.541446 ◽

2007 ◽

Author(s):

Paola Chiarugi

Keyword(s):

Focal Adhesions ◽

Redox Signaling ◽

Stress Fibers ◽

Oncogenic Ras

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Faculty Opinions recommendation of Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104723.560791 ◽

2008 ◽

Author(s):

Michael Weber

Keyword(s):

Cell Death ◽

Cancer Cells ◽

Synthetic Lethal ◽

Oncogenic Ras ◽

Nonapoptotic Cell Death

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Faculty of 1000 evaluation for Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.1818967.1865062 ◽

2010 ◽

Author(s):

Channing Der

Keyword(s):

Tumor Progression ◽

Oncogenic Ras

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Faculty Opinions recommendation of Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726668906.793535943 ◽

2017 ◽

Author(s):

Robert Lewis

Keyword(s):

Small Molecule ◽

Inactive State ◽

Oncogenic Ras ◽

Ras Signalling

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Faculty Opinions recommendation of Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727280568.793528542 ◽

2017 ◽

Author(s):

Eytan Ruppin ◽

Welles Robinson

Keyword(s):

Gene Networks ◽

Synthetic Lethal ◽

Gene Essentiality ◽

Oncogenic Ras ◽

Synthetic Lethal Interactions

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Faculty Opinions recommendation of Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732320711.793542716 ◽

2018 ◽

Author(s):

Shizuo Akira

Keyword(s):

Ras Signaling ◽

Oncogenic Ras

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Faculty Opinions recommendation of Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9113962.10228054 ◽

2011 ◽

Author(s):

Andreas Villunger

Keyword(s):

Cell Death ◽

Clonogenic Survival ◽

Autophagic Cell Death ◽

Beclin 1 ◽

Induced Expression ◽

Oncogenic Ras

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