scholarly journals The risk of distant metastases in patients with gynecologic cancers after surgery: a population-based study

Aging ◽  
2021 ◽  
Author(s):  
Yi-Hsuan Hsiao ◽  
Pei-Ni Chen ◽  
Min-Chien Hsin ◽  
Po-Hui Wang ◽  
Jing-Yang Huang ◽  
...  
Keyword(s):  
Distant Metastases ◽  
Population Based ◽  
Gynecologic Cancers ◽  
Population Based Study

Differences in outcome between right- and left-sided colon cancer: A population based study.

2013 ◽  
Vol 31 (4_suppl) ◽  
pp. 493-493 ◽  
Author(s):  
Frits Aarts ◽  
Ignace de Hingh ◽  
Johannes HW de Wilt ◽  
Valery E. P. Lemmens ◽  
Rob H.A. Verhoeven
Keyword(s):  
Colon Cancer ◽  
Colon Carcinoma ◽  
Survival Data ◽  
Mucinous Adenocarcinoma ◽  
Age Groups ◽  
Treatment Strategies ◽  
Distant Metastases ◽  
Population Based ◽  
Population Based Study ◽  
The Impact

493 Background: Colon cancer is the second most frequent cause of cancer death, with an increasing incidence during the last decade. Recently, there is an increased interest in possible differences in outcome after surgery between right- and left-sided colon carcinoma (RCC and LCC). Methods: A population based study was performed in the south part of the Netherlands covering a region with more than 2 million inhabitants. Patients suffering from either RCC or LCC, excluding rectal cancer, were compared with regard to epidemiological, clinical and histological parameters as well as survival data. A Cox proportional hazard model was used to estimate the impact of different parameters on survival. Results: The data of 12,731 patients with colon cancer from January first 2000 and December 31 2010 were analyzed. Of these, 42% was RCC and 55% was LCC. In the remaining 3% of patients the location was not otherwise specified. In comparison with LCC, the majority of RCC patients were female (53% vs. 46%) and older (42% vs 34% > 75 years). The majority of RCC (77%) and LCC (87%) was non-mucinous adenocarcinoma. In RCC, 18% of tumors were mucinous adenocarcinoma vs 10% in LCC, p< 0.001. Well differentiated tumors were more common in LCC, 70% vs 58% in RCC Moderately and poorly differentiated tumors were more present in RCC compared to LCC (23% vs 13%, p<0.0001). Stage I tumors were more common for LCC vs stage II-IV tumors in RCC, p<0.0001. In RCC 1-9 lymph nodes were found in 37% vs 51% in LCC. In RCC 49% >10 LN were found vs 34% in LCC. No difference was found between anatomical sites regarding tumor positive LN, nor in LN ratio. Synchronous distant metastases were present in 30% of RCC vs 25% in LCC. Median overall survival in RCC was 46 months vs 60 months in LCC, p<0.0001. Survival differed between age groups and location and was worse for RCC with age 45-59 yrs: RCC vs LCC p<0.0008, age 60-74 yrs: RCC vs LCC, p<0.0006). Also, in T4 tumors, survival was worse for RCC, p<0.007. Conclusions: Prognosis of colon carcinoma is correlated to anatomical distribution with a significantly worse prognosis for RCC patients. Since RCC is more common in people of older age and the incidence is increasing, these findings may have future implications for the planning of treatment strategies.

scholarly journals Clinicopathological characteristics and survival of lymphoepithelial carcinoma of the oral cavity and pharynx: a population-based study

2019 ◽  
Author(s):  
Jinbo Bai ◽  
Fen Zhao ◽  
Shuang Pan
Keyword(s):  
Lymph Node ◽  
Oral Cavity ◽  
Survival Time ◽  
Old Age ◽  
Survival Rates ◽  
Distant Metastases ◽  
Population Based ◽  
Clinicopathological Characteristics ◽  
Lymphoepithelial Carcinoma ◽  
Population Based Study

AbstractLymphoepithelial carcinoma (LEC) of the oral cavity and pharynx is uncommon, and the characteristics and survival remains unclear. The present study aims to describe the clinicopathological characteristics and determine the factors associated with survival of this uncommon cancer. A population-based study was carried out to investigate clinical characteristics and prognosis of LEC of the oral cavity and pharynx using the data from Surveillance, Epidemiology and End Results (SEER) database between 1988 and 2013. The propensity-matched analysis was conducted for prognostic analysis, and a prognostic nomogram was also constructed. Totally, 1025 patients with LEC of the oral cavity and pharynx were identified, including 769 nasopharyngeal LEC patients and 256 non-nasopharyngeal LEC patients. The median OS of all LEC patients was 232.0m (95% CI 169.0-258.0). The 1-, 5-, 10- and 20-year survival rates were 92.9%, 72.9%, 59.3%, and 46.8%, respectively. Surgery could significantly prolong the survival time of LEC patients (P<0.01, mOS: 190m vs. 255m). Radiotherapy, as well as radiotherapy after surgery, could prolong the mOS (P<0.01 for both). The survival analysis demonstrated that old age (>60 years), lymph node (N3) and distant metastases were independent factors for poor survival, whereas radiotherapy and surgery were independent factors for favorable survival. No significant differences in survival time between nasopharyngeal LEC and non-nasopharyngeal LEC patients were observed. The prognostic nomogram was established base on five independent prognostic factors (C-index=0.70; 95% CI 0.66-0.74). In conclusion, LEC of the oral cavity and pharynx is a rare disease, and old age, lymph node and distant metastases, surgery and radiotherapy were significantly associated with prognosis. The prognostic nomogram could be used to make individual predictions of OS.

A population-based study on post-operative outcomes of pelvic exenteration for gynecologic cancers

2012 ◽  
Vol 125 ◽  
pp. S164
Author(s):  
K. Hansen ◽  
J. Lin ◽  
S. Beriwal ◽  
J. Kelley ◽  
T. Krivak ◽  
...  
Keyword(s):  
Pelvic Exenteration ◽  
Population Based ◽  
Gynecologic Cancers ◽  
Population Based Study ◽  
Operative Outcomes

scholarly journals Pattern and risk factors for distant metastases in gastrointestinal neuroendocrine neoplasms: a population-based study

2018 ◽  
Vol 7 (6) ◽  
pp. 2699-2709 ◽  
Author(s):  
Wen Cai ◽  
Yinuo Tan ◽  
Weiting Ge ◽  
Kefeng Ding ◽  
Hanguang Hu
Keyword(s):  
Risk Factors ◽  
Distant Metastases ◽  
Population Based ◽  
Neuroendocrine Neoplasms ◽  
Population Based Study
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