scholarly journals Long non-coding RNA CRNDE as potential biomarkers facilitate inflammation and apoptosis in alcoholic liver disease

Aging ◽  
2021 ◽  
Author(s):  
Yifeng Yan ◽  
Liang Ren ◽  
Yan Liu ◽  
Liang Liu
Keyword(s):  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Non Coding Rna ◽  
Long Non Coding Rna ◽  
Potential Biomarkers

scholarly journals Potential Biomarkers for Therapeutic Monitoring and Clinical Outcome in Breast Cancer

2021 ◽  
Author(s):  
Yuki Yamamoto ◽  
Sabrina La Salvia ◽  
Sahoo Susmita ◽  
Hidetoshi Tahara
Keyword(s):  
Expression Profiles ◽  
Therapeutic Targets ◽  
Transfer Rna ◽  
Therapeutic Monitoring ◽  
Transfer Rnas ◽  
Non Coding Rna ◽  
Tumor Tissues ◽  
Non Coding Rnas ◽  
Long Non Coding Rna ◽  
Potential Biomarkers

Non-coding RNAs are a species of RNA that are not translated to proteins. These include transfer RNAs and ribosomal RNAs, microRNAs, transfer RNA-derived fragments, and long non-coding RNA. It is known that expression levels of some non-coding RNAs included microRNAs are altered in cancer cells or tumor tissues. Moreover, expression profiles of such non-coding RNAs correlate between tissues and body fluids. Therefore, several non-coding RNAs are being used as diagnostic/prognosis biomarkers or therapeutic targets in cancer. In this chapter, we review about representative non-coding RNAs and introduce especially microRNA as diagnosis/prognosis biomarkers and therapeutic targets.

scholarly journals Definition and review on a category of long non-coding RNA: Atherosclerosis-associated circulating lncRNA (ASCLncRNA)

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10001
Author(s):  
Shanshan Lu ◽  
Qin Liang ◽  
Yanqing Huang ◽  
Fanming Meng ◽  
Junwen Liu
Keyword(s):  
Noncoding Rnas ◽  
Circulatory System ◽  
Modern Society ◽  
Apoptotic Bodies ◽  
Non Invasive ◽  
Physiological Processes ◽  
Non Coding Rna ◽  
Definition Of ◽  
Long Non Coding Rna ◽  
Potential Biomarkers

Atherosclerosis (AS) is one of the most common cardiovascular system diseases which seriously affects public health in modern society. Finding potential biomarkers in the complicated pathological progression of AS is of great significance for the prevention and treatment of AS. Studies have shown that long noncoding RNAs (lncRNAs) can be widely involved in the regulation of many physiological processes, and have important roles in different stages of AS formation. LncRNAs can be secreted into the circulatory system through exosomes, microvesicles, and apoptotic bodies. Recently, increasing studies have been focused on the relationships between circulating lncRNAs and AS development. The lncRNAs in circulating blood are expected to be new non-invasive diagnostic markers for monitoring the progression of AS. We briefly reviewed the previously reported lncRNA transcripts which related to AS development and detectable in circulating blood, including ANRIL, SENCR, CoroMarker, LIPCAR, HIF1α-AS1, LncRNA H19, APPAT, KCNQ1OT1, LncPPARδ, LincRNA-p21, MALAT1, MIAT, and UCA1. Further researches and a definition of atherosclerosis-associated circulating lncRNA (ASCLncRNA) were also discussed.

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