scholarly journals The relationship between plasma free fatty acids, cognitive function and structural integrity of the brain in middle-aged healthy humans

Aging ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 22078-22091
Author(s):  
Markus Herrmann ◽  
Sebastian Simstich ◽  
Günter Fauler ◽  
Edith Hofer ◽  
Eva Fritz-Petrin ◽  
...  
Cardiology ◽  
1972 ◽  
Vol 57 (1-2) ◽  
pp. 51-54 ◽  
Author(s):  
L.A. Carlson ◽  
B.W. Lassers ◽  
M.L. Wahlqvist ◽  
L. Kaijser

1991 ◽  
Vol 197 (2) ◽  
pp. 95-104 ◽  
Author(s):  
J.J.H. Smit ◽  
D.K. Bosman ◽  
G.G.A. Jörning ◽  
J.G.de Haan ◽  
M.A.W. Maas ◽  
...  

1972 ◽  
Vol 51 (9) ◽  
pp. 2388-2398 ◽  
Author(s):  
Hans-Jürgen Quabbe ◽  
Hans-Jürgen Bratzke ◽  
Ulrike Siegers ◽  
Kadip Elban

1996 ◽  
Vol 14 (2) ◽  
pp. 229-235 ◽  
Author(s):  
Jan Filipovsky ◽  
Pierre Ducimetiere ◽  
Eveline Eschwege ◽  
Jacques L. Richard ◽  
Gabriel Rosselin ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5163
Author(s):  
Ting Hu ◽  
Quanfei Zhu ◽  
Yuning Hu ◽  
Ghulam Mustafa Kamal ◽  
Yuqi Feng ◽  
...  

Free fatty acids serve as important bioactive molecules in the brain. They are involved in message transfer in the brain. There are many reports available in the literature regarding the role of cerebral fatty acids in message transfer; however, most of the studies are mainly focused on limited fatty acid species or only a few specific brain regions. To understand the relationship between cerebral functions and free fatty acids, it is necessary to investigate the distribution of the free fatty acids among different regions in the whole brain. In this study, free fatty acids were extracted from different brain regions and analyzed qualitatively and quantitatively using the stable isotopic labeling liquid chromatography–mass spectrometry approach. In total, 1008 potential free fatty acids were detected in the whole brain out of which 38 were found to be commonly present in all brain regions. Among different brain regions, the highest and the smallest amounts of potential free fatty acids were detected in the olfactory bulb and cerebellum, respectively. From a statistical point of view, 4-methyl-2-oxovaleric acid, cis-11, 14-eicosadienoic acid, tridecanoic acid, myristic acid, nonadecanoic acid, and arachidic acid were found to significantly vary among the four different brain regions (olfactory bulb, occipital lobe, hippocampus, and cerebellum). The variation in the composition of free fatty acids among different brain regions may be very important for investigating the relationship between free fatty acids and functions of cerebral regions.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1812-P
Author(s):  
MARIA D. HURTADO ◽  
J.D. ADAMS ◽  
MARCELLO C. LAURENTI ◽  
CHIARA DALLA MAN ◽  
CLAUDIO COBELLI ◽  
...  

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