scholarly journals Integrated analysis of long non-coding RNAs (lncRNAs) and mRNA expression profiles identifies lncRNA PRKG1-AS1 playing important roles in skeletal muscle aging

Aging ◽  
2021 ◽  
Author(s):  
Yan Zheng ◽  
Ting Liu ◽  
Qun Li ◽  
Jie Li
Keyword(s):  
Skeletal Muscle ◽  
Mrna Expression ◽  
Expression Profiles ◽  
Integrated Analysis ◽  
Muscle Aging ◽  
Non Coding Rnas ◽  
Skeletal Muscle Aging

Integrated analysis of non-coding RNA and mRNA expression profiles of 2 pig breeds differing in muscle traits

2017 ◽  
Vol 95 (3) ◽  
pp. 1092 ◽  
Author(s):  
J. Sun ◽  
M. Xie ◽  
Z. Huang ◽  
H. Li ◽  
T. chen ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Expression Profiles ◽  
Integrated Analysis ◽  
Pig Breeds ◽  
Non Coding Rna

scholarly journals Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profiles in Testes of Calves and Sexually Mature Wandong Bulls (Bos taurus)

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2006
Author(s):  
Hongyu Liu ◽  
Ibrar Muhammad Khan ◽  
Huiqun Yin ◽  
Xinqi Zhou ◽  
Muhammad Rizwan ◽  
...  
Keyword(s):  
Target Genes ◽  
Expression Profiles ◽  
Age Groups ◽  
Adherens Junction ◽  
Integrated Analysis ◽  
Sequencing Data ◽  
Non Coding Rna ◽  
Non Coding Rnas ◽  
Rna Interaction ◽  
Long Non Coding Rna

The mRNAs and long non-coding RNAs axes are playing a vital role in the regulating of post-transcriptional gene expression. Thereby, elucidating the expression pattern of mRNAs and long non-coding RNAs underlying testis development is crucial. In this study, mRNA and long non-coding RNAs expression profiles were investigated in 3-month-old calves and 3-year-old mature bulls’ testes by total RNA sequencing. Additionally, during the gene level analysis, 21,250 mRNAs and 20,533 long non-coding RNAs were identified. As a result, 7908 long non-coding RNAs (p-adjust < 0.05) and 5122 mRNAs (p-adjust < 0.05) were significantly differentially expressed between the distinct age groups. In addition, gene ontology and biological pathway analyses revealed that the predicted target genes are enriched in the lysine degradation, cell cycle, propanoate metabolism, adherens junction and cell adhesion molecules pathways. Correspondingly, the RT-qPCR validation results showed a strong consistency with the sequencing data. The source genes for the mRNAs (CCDC83, DMRTC2, HSPA2, IQCG, PACRG, SPO11, EHHADH, SPP1, NSD2 and ACTN4) and the long non-coding RNAs (COX7A2, COX6B2, TRIM37, PRM2, INHBA, ERBB4, SDHA, ATP6VOA2, FGF9 and TCF21) were found to be actively associated with bull sexual maturity and spermatogenesis. This study provided a comprehensive catalog of long non-coding RNAs in the bovine testes and also offered useful resources for understanding the differences in sexual development caused by the changes in the mRNA and long non-coding RNA interaction expressions between the immature and mature stages.

scholarly journals Integrated analysis of miRNA and mRNA expression profiles in tilapia gonads at an early stage of sex differentiation

BMC Genomics ◽  
2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Wenjing Tao ◽  
Lina Sun ◽  
Hongjuan Shi ◽  
Yunying Cheng ◽  
Dongneng Jiang ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Early Stage ◽  
Expression Profiles ◽  
Sex Differentiation ◽  
Integrated Analysis

scholarly journals Integrated analysis of microRNA and mRNA expression profiles in abdominal adipose tissues in chickens

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
H. Y. Huang ◽  
R. R. Liu ◽  
G. P. Zhao ◽  
Q.H. Li ◽  
M. Q. Zheng ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Expression Profiles ◽  
Integrated Analysis ◽  
Adipose Tissues
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