scholarly journals Piccolo is essential for the maintenance of mouse retina but not cochlear hair cell function

Aging ◽  
2021 ◽  
Author(s):  
Peipei Li ◽  
Zhuchun Lin ◽  
Yachun An ◽  
Jing Lin ◽  
Aizhen Zhang ◽  
...  
Keyword(s):  
Hair Cell ◽  
Cell Function ◽  
Mouse Retina ◽  
Cochlear Hair Cell

scholarly journals CLRN1 Is Nonessential in the Mouse Retina but Is Required for Cochlear Hair Cell Development

PLoS Genetics ◽  
2009 ◽  
Vol 5 (8) ◽  
pp. e1000607 ◽  
Author(s):  
Scott F. Geller ◽  
Karen I. Guerin ◽  
Meike Visel ◽  
Aaron Pham ◽  
Edwin S. Lee ◽  
...  
Keyword(s):  
Hair Cell ◽  
Cell Development ◽  
Mouse Retina ◽  
Cochlear Hair Cell

scholarly journals Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function

10.1038/ng842 ◽  
2002 ◽  
Vol 30 (3) ◽  
pp. 277-284 ◽  
Author(s):  
Kiyoto Kurima ◽  
Linda M. Peters ◽  
Yandan Yang ◽  
Saima Riazuddin ◽  
Zubair M. Ahmed ◽  
...  
Keyword(s):  
Hair Cell ◽  
Cell Function ◽  
Cochlear Hair Cell ◽  
Novel Gene

Histological evaluation of cochlear hair cell damage from noise-induced hearing loss in chinchillas

1990 ◽  
Vol 48 (3) ◽  
pp. 332-333
Author(s):  
R.V. Harrison ◽  
R.J. Mount ◽  
P. White ◽  
N. Fukushima
Keyword(s):  
Hair Cell ◽  
Evoked Potential ◽  
Cell Damage ◽  
Acoustic Trauma ◽  
Histological Evaluation ◽  
Cell Integrity ◽  
Functional Changes ◽  
Cochlear Hair Cell ◽  
Left And Right ◽  
Contralateral Ear

In studies which attempt to define the influence of various factors on recovery of hair cell integrity after acoustic trauma, an experimental and a control ear which initially have equal degrees of damage are required. With in a group of animals receiving an identical level of acoustic trauma there is more symmetry between the ears of each individual, in respect to function, than between animals. Figure 1 illustrates this, left and right cochlear evoked potential (CAP) audiograms are shown for two chinchillas receiving identical trauma. For this reason the contralateral ear is used as control.To compliment such functional evaluations we have devised a scoring system, based on the condition of hair cell stereocilia as revealed by scanning electron microscopy, which permits total stereociliar damage to be expressed numerically. This quantification permits correlation of the degree of structural pathology with functional changes. In this paper wereport experiments to verify the symmetry of stereociliar integrity between two ears, both for normal (non-exposed) animals and chinchillas in which each ear has received identical noise trauma.

scholarly journals Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death

2014 ◽  
Vol 89 (3) ◽  
pp. 415-421 ◽  
Author(s):  
Le Nguyen Uyen Chi ◽  
Keiji Tabuchi ◽  
Mariko Nakamagoe ◽  
Masahiro Nakayama ◽  
Bungo Nishimura ◽  
...  
Keyword(s):  
Cell Death ◽  
Hair Cell ◽  
Cochlear Hair Cell ◽  
Hair Cell Death ◽  
Sphingomyelin Cycle
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