scholarly journals Long non-coding RNA TP73-AS1 is a potential immune related prognostic biomarker for glioma

Aging ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 5638-5649
Author(s):  
Bo Zhang ◽  
Qinglin Li ◽  
Bin Wu ◽  
Shuyuan Zhang ◽  
Liwen Li ◽  
...  
2020 ◽  
Vol 6 (3) ◽  
pp. 16215-16226
Author(s):  
Daniel Rodrigues Bastos ◽  
Jean Michel Rocha Sampaio Leite ◽  
Mércia Patrícia Ferreira Conceição ◽  
Cesar Augusto Sam Tiago Vilanova-Costa ◽  
Antonio Márcio Teodoro Cordeiro Silva ◽  
...  

2018 ◽  
Vol 481 ◽  
pp. 99-107 ◽  
Author(s):  
Chaojie Liang ◽  
Bing Zhang ◽  
Hua Ge ◽  
Yingchen Xu ◽  
Guangming Li ◽  
...  

2020 ◽  
Author(s):  
Lijun Lei ◽  
Lianbing Sheng ◽  
Lingyuan Wu ◽  
Jiaojing Liu ◽  
Bin Wei ◽  
...  

Abstract Background We performed this meta-analysis to elucidate whether the expression of PlncRNA-1 might serve as an effective prognostic marker for various cancers. Methods We conducted a database search of PubMed, ScienceDirect, Embase, Web of Science and CNKI database (up to Oct 31, 2019). The pooled hazard ratio (HR), odds ratio (OR) and 95% confidence interval (CI) were used to estimate the strength of the relationship between PlncRNA-1 expression and the clinical prognosis of cancer patients. Results The results showed that elevated PlncRNA-1 expression predicted a poor OS with pooled HRs of 1.43 (95% CI: 1.25-1.63, I 2 =63.1%, P=0.004). Likewise, we found that advanced tumour stages were associated with upregulated PlncRNA-1 expression in various cancer types (III–IV vs I–II: OR=2.79, 95% CI: 1.76-4.41, I 2 =0%, P=0.822),patients with high PlncRNA-1 expression might have an increased risk of large tumours (OR=2.03, 95% CI: 1.31-3.14, I 2 =67.1%, P=0.028). Conclusions PlncRNA-1 might be used as a prognostic biomarker and as a tool for the early detection of various tumours.


2016 ◽  
Vol 36 (1) ◽  
pp. 215-222 ◽  
Author(s):  
ZHENBO TU ◽  
DU HE ◽  
XINZHOU DENG ◽  
MENG XIONG ◽  
XIAOXING HUANG ◽  
...  

Tumor Biology ◽  
2017 ◽  
Vol 39 (4) ◽  
pp. 101042831769836 ◽  
Author(s):  
Ganesan Arunkumar ◽  
Arunagiri Kuha Deva Magendhra Rao ◽  
Mayakannan Manikandan ◽  
Kanagaraj Arun ◽  
Vilvanathan Vinothkumar ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Siying Wang ◽  
Zhenyao Chen ◽  
Jingyao Gu ◽  
Xin Chen ◽  
Zhaoxia Wang

Long non-coding RNA (lncRNA) PCAT6 is a member of the Prostate Cancer Associated Transcripts family of molecules. In this review, we focus on the latest studies involving PCAT6 in the diagnosis, treatment, and prognosis of malignant tumors of the digestive, respiratory, urinary, reproductive, motion, and nervous systems. PCAT6 was found to be highly expressed in gastric cancer, colon cancer, hepatocellular carcinoma, lung cancer, bladder cancer, ovarian cancer, breast cancer, cervical cancer, osteosarcoma, glioblastoma, and other tumors. PCAT6 can promote the development and progression of different types of malignant tumors through various mechanisms. Overall, these findings suggest that PCAT6 may play an increasingly vital role in the clinical assessment of these malignant tumors. It can function as an oncogene and may be used as a potential new prognostic biomarker of these tumors.


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