scholarly journals Inhibiting Th1/2 cells influences hepatic capillarization by adjusting sinusoidal endothelial fenestrae through Rho-ROCK-myosin pathway

Aging ◽  
2021 ◽  
Author(s):  
Yuesi Zhong ◽  
Mingxing Xu ◽  
Jingxiong Hu ◽  
Xi Huang ◽  
Nan Lin ◽  
...  
Keyword(s):  
Sinusoidal Endothelial Fenestrae

Ultrastructural Alterations in Sinusoidal Endothelial Fenestrae as a Result of Hypoxia

1976 ◽  
Vol 34 ◽  
pp. 168-169
Author(s):  
Waykin Nopanitaya ◽  
Raeford E. Brown ◽  
Joe W. Grisham ◽  
Johnny L. Carson
Keyword(s):  
Endothelial Cells ◽  
Experimental Model ◽  
Hepatic Lobule ◽  
Ultrastructural Alterations ◽  
Large Type ◽  
Sinusoidal Endothelial Fenestrae ◽  
General Size ◽  
Sem Studies

Mammalian endothelial cells lining hepatic sinusoids have been found to be widely fenestrated. Previous SEM studies (1,2) have noted two general size catagories of fenestrations; large fenestrae were distributed randomly while the small type occurred in groups. These investigations also reported that large fenestrae were more numerous and larger in the endothelial cells at the afferent ends of sinusoids or around the portal areas, whereas small fenestrae were more numerous around the centrilobular portion of the hepatic lobule. It has been further suggested that under some physiologic conditions small fenestrae could fuse and subsequently become the large type, but this is, as yet, unproven.We have used a reproducible experimental model of hypoxia to study the ultrastructural alterations in sinusoidal endothelial fenestrations in order to investigate the origin of occurrence of large fenestrae.

scholarly journals Endothelin-1 Suppresses Plasma Membrane Ca++-ATPase, Concomitant with Contraction of Hepatic Sinusoidal Endothelial Fenestrae

2003 ◽  
Vol 162 (2) ◽  
pp. 557-566 ◽  
Author(s):  
Hiroaki Yokomori ◽  
Masaya Oda ◽  
Mariko Ogi ◽  
Kazunori Yoshimura ◽  
Masahiko Nomura ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Endothelin 1 ◽  
Sinusoidal Endothelial Fenestrae

Effects of endothelin receptor antagonists on hepatic hemodynamics and sinusoidal endothelial fenestrae in cirrhotic rats

2000 ◽  
Vol 118 (4) ◽  
pp. A968 ◽  
Author(s):  
Norihito Watanabe ◽  
Shinji Takashimizu ◽  
Yasuhiro Nishizaki ◽  
Kazuya Kawazoe ◽  
Tomoaki Ilzuka ◽  
...  
Keyword(s):  
Endothelin Receptor Antagonists ◽  
Endothelin Receptor ◽  
Receptor Antagonists ◽  
Hepatic Hemodynamics ◽  
Sinusoidal Endothelial Fenestrae

Hepatic sinusoidal endothelial fenestrae express plasma membrane Ca++ pump and Ca++ Mg++ -ATPase

2000 ◽  
Vol 20 (6) ◽  
pp. 458-464 ◽  
Author(s):  
Hiroaki Yokomori ◽  
Masaya Oda ◽  
Mariko Ogi ◽  
Yoshitaka Kamegaya ◽  
Nobuhiro Tsukada ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Ca Pump ◽  
Sinusoidal Endothelial Fenestrae

scholarly journals Rho modulates hepatic sinusoidal endothelial fenestrae via regulation of the actin cytoskeleton in rat endothelial cells

2004 ◽  
Vol 84 (7) ◽  
pp. 857-864 ◽  
Author(s):  
Hiroaki Yokomori ◽  
Kazunori Yoshimura ◽  
Shinsuke Funakoshi ◽  
Toshihiro Nagai ◽  
Kayo Fujimaki ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Actin Cytoskeleton ◽  
Sinusoidal Endothelial Fenestrae
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