scholarly journals Mixed-location cerebral microbleeds as a biomarker of neurodegeneration in a memory clinic population

Aging ◽  
2019 ◽  
Vol 11 (22) ◽  
pp. 10581-10596
Author(s):  
Bibek Gyanwali ◽  
Muhammad Amin Shaik ◽  
Chuen Seng Tan ◽  
Henri Vrooman ◽  
Narayanaswamy Venketasubramanian ◽  
...  
Keyword(s):  
Cerebral Microbleeds ◽  
Memory Clinic ◽  
Clinic Population

Incidence of cerebral microbleeds: A longitudinal study in a memory clinic population

Neurology ◽  
2010 ◽  
Vol 74 (24) ◽  
pp. 1954-1960 ◽  
Author(s):  
J. D. C. Goos ◽  
W. J. P. Henneman ◽  
J. D. Sluimer ◽  
H. Vrenken ◽  
I. C. Sluimer ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cerebral Microbleeds ◽  
Memory Clinic ◽  
Clinic Population

scholarly journals P1-329: RELATION OF CLINICAL BLEEDING RISK SCORES WITH CEREBRAL MICROBLEEDS AND CORTICAL SUPERFICIAL SIDEROSIS IN A MEMORY CLINIC POPULATION

2019 ◽  
Vol 15 ◽  
pp. P370-P371
Author(s):  
Aline Mendes ◽  
François Herrmann ◽  
Max Scheffler ◽  
Gemma Gabriel ◽  
Fabien Carruzzo ◽  
...  
Keyword(s):  
Bleeding Risk ◽  
Cerebral Microbleeds ◽  
Risk Scores ◽  
Superficial Siderosis ◽  
Memory Clinic ◽  
Clinic Population ◽  
Cortical Superficial Siderosis

Mixed-Location Cerebral Microbleeds: An Imaging Biomarker for Cerebrovascular Pathology in Cognitive Impairment and Dementia in a Memory Clinic Population

2019 ◽  
Vol 71 (4) ◽  
pp. 1309-1320 ◽  
Author(s):  
Bibek Gyanwali ◽  
Muhammad Amin Shaik ◽  
Narayanaswamy Venketasubramanian ◽  
Christopher Chen ◽  
Saima Hilal
Keyword(s):  
Cognitive Impairment ◽  
Cerebral Microbleeds ◽  
Imaging Biomarker ◽  
Memory Clinic ◽  
Cerebrovascular Pathology ◽  
Clinic Population

P1-371: New research criteria for the diagnosis of Alzheimer's disease applied in a memory clinic population

2008 ◽  
Vol 4 ◽  
pp. T327-T328 ◽  
Author(s):  
Femke H. Bouwman ◽  
Nicolaas A. Verwey ◽  
Martin Klein ◽  
Yolande A.L. Pijnenburg ◽  
Astrid Kok ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Memory Clinic ◽  
New Research ◽  
Research Criteria ◽  
Clinic Population

O5-02-02: Concordance between CSF biomarkers and [11C]PIB PET in a memory clinic population

2013 ◽  
Vol 9 ◽  
pp. P830-P830 ◽  
Author(s):  
Marissa Zwan ◽  
Argonde van Harten ◽  
Rik Ossenkoppele ◽  
Femke Bouwman ◽  
Charlotte Teunissen ◽  
...  
Keyword(s):  
Csf Biomarkers ◽  
Memory Clinic ◽  
Clinic Population

scholarly journals Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1)

2018 ◽  
Vol 13 (5) ◽  
pp. 454-468 ◽  
Author(s):  
Andreas Charidimou ◽  
Sara Shams ◽  
Jose R Romero ◽  
Jie Ding ◽  
Roland Veltkamp ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
High Risk ◽  
Intracerebral Hemorrhage ◽  
Meta Analysis ◽  
Population Based ◽  
Cerebral Microbleeds ◽  
Clinical Settings ◽  
Memory Clinic ◽  
Increased Risk ◽  
Stroke Death

Background Cerebral microbleeds can confer a high risk of intracerebral hemorrhage, ischemic stroke, death and dementia, but estimated risks remain imprecise and often conflicting. We investigated the association between cerebral microbleeds presence and these outcomes in a large meta-analysis of all published cohorts including: ischemic stroke/TIA, memory clinic, “high risk” elderly populations, and healthy individuals in population-based studies. Methods Cohorts (with > 100 participants) that assessed cerebral microbleeds presence on MRI, with subsequent follow-up (≥3 months) were identified. The association between cerebral microbleeds and each of the outcomes (ischemic stroke, intracerebral hemorrhage, death, and dementia) was quantified using random effects models of (a) unadjusted crude odds ratios and (b) covariate-adjusted hazard rations. Results We identified 31 cohorts ( n = 20,368): 19 ischemic stroke/TIA ( n = 7672), 4 memory clinic ( n = 1957), 3 high risk elderly ( n = 1458) and 5 population-based cohorts ( n = 11,722). Cerebral microbleeds were associated with an increased risk of ischemic stroke (OR: 2.14; 95% CI: 1.58–2.89 and adj-HR: 2.09; 95% CI: 1.71–2.57), but the relative increase in future intracerebral hemorrhage risk was greater (OR: 4.65; 95% CI: 2.68–8.08 and adj-HR: 3.93; 95% CI: 2.71–5.69). Cerebral microbleeds were an independent predictor of all-cause mortality (adj-HR: 1.36; 95% CI: 1.24–1.48). In three population-based studies, cerebral microbleeds were independently associated with incident dementia (adj-HR: 1.35; 95% CI: 1.00–1.82). Results were overall consistent in analyses stratified by different populations, but with different degrees of heterogeneity. Conclusions Our meta-analysis shows that cerebral microbleeds predict an increased risk of stroke, death, and dementia and provides up-to-date effect sizes across different clinical settings. These pooled estimates can inform clinical decisions and trials, further supporting cerebral microbleeds role as biomarkers of underlying subclinical brain pathology in research and clinical settings.

Cerebral White Matter Lesions have Low Impact on Cognitive Function in a Large Elderly Memory Clinic Population

2018 ◽  
Vol 63 (3) ◽  
pp. 1129-1139 ◽  
Author(s):  
Jules J. Claus ◽  
Mirthe Coenen ◽  
Salka S. Staekenborg ◽  
Jacqueline Schuur ◽  
Caroline E.M. Tielkes ◽  
...  
Keyword(s):  
Cognitive Function ◽  
White Matter ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Memory Clinic ◽  
Cerebral White Matter Lesions ◽  
Clinic Population

scholarly journals P3-357: MIXED MICROBLEEDS AS A BIOMARKER OF NEURODEGENERATION IN A MEMORY CLINIC POPULATION

2019 ◽  
Vol 15 ◽  
pp. P1081-P1082
Author(s):  
Bibek Gyanwali ◽  
Muhammad Amin Shaik ◽  
Chuen Seng Tan ◽  
Henri A. Vrooman ◽  
Narayanaswamy Venketasubramanian ◽  
...  
Keyword(s):  
Memory Clinic ◽  
Clinic Population

scholarly journals A - 32The Shepherd Verbal Learning Test: Simple 10-Item Supraspan Test for Use in a Memory Clinic Population

2018 ◽  
Vol 33 (6) ◽  
pp. 703-794
Author(s):  
N Norheim ◽  
A Kissinger-Knox ◽  
M Cheatham ◽  
K Mulligan ◽  
F Webbe
Keyword(s):  
Verbal Learning ◽  
Memory Clinic ◽  
Learning Test ◽  
Clinic Population

scholarly journals Biomarker profiles in a memory clinic population according to new Alzheimer diagnostic framework

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Ulf Öhlund ◽  
Fleur Wiggenraad ◽  
Göran Hagman ◽  
Anna Rosenberg ◽  
Miia Kivipelto
Keyword(s):  
Memory Clinic ◽  
Diagnostic Framework ◽  
Clinic Population
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