scholarly journals Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels

Author(s):  
Hande Peynirci ◽  
Canan Ersoy ◽  
Vildan Gürsoy ◽  
Ayten Girgin ◽  
Mehmet Ali Aşık ◽  
...  
2003 ◽  
Vol 82 (5) ◽  
pp. 390-393 ◽  
Author(s):  
Gideon Bahar ◽  
Daniel Mimouni ◽  
Meora Feinmesser ◽  
Michael David ◽  
Aharon Popovzer ◽  
...  

Calciphylaxis is a rare disorder in patients with chronic renal failure that is characterized by ischemic necrotic skin lesions. The prognosis is grave and mortality is high (80%). The precise mechanism of calciphylaxis is still unknown, but in addition to chronic renal failure, elevated parathyroid hormone levels appear to play a role. The role of parathyroidectomy in treating affected patients is questionable. In this article, we describe the case of a patient with chronic renal failure who developed rapidly progressive subcutaneous calcifications and ulcerations in the lower extremities. These lesions regressed following subtotal parathyroidectomy. We also review the literature on calciphylaxis, with a focus on treatment options.


2003 ◽  
Vol 18 (12) ◽  
pp. 1236-1241 ◽  
Author(s):  
Simon Waller ◽  
Sarah Ledermann ◽  
Richard Trompeter ◽  
William van’t Hoff ◽  
Deborah Ridout ◽  
...  

2016 ◽  
Vol 5 (5) ◽  
pp. 601-606 ◽  
Author(s):  
Gang-Yong Wu ◽  
Bai-Da Xu ◽  
Ting Wu ◽  
Xiao-Ying Wang ◽  
Tian-Xiao Wang ◽  
...  

2013 ◽  
Vol 154 (51) ◽  
pp. 2025-2036
Author(s):  
László Kovács ◽  
Éva Virágh ◽  
Dóra Balogh ◽  
Bernadette Kálmán ◽  
Zoltán Lőcsei ◽  
...  

Introduction: Parathyroid hormone levels provide important information in chronic renal failure. Aim: To compare parathyroid hormone levels measured by two assays in correlation with vitamin D supply. Method: Parathyroid hormone and 25-hydroxi-vitamin-D were determined in 104 patients (31 patients with chronic renal failure without renal replacement therapy, 36 patients treated with peritoneal dialysis and 37 patients treated with hemodialysis). Results: Good correlation was found between results of the two parathyroid hormone methods, but the intact parathyroid hormone levels were higher than the biointact values. 87% and 13% of the patients had vitamin-D deficiency and insufficiency, respectively. The frequency of serious vitamin-D deficiency was higher in the peritoneal dialysis than in the hemodialysis group. Intact parathyroid hormone levels were different in dialysed patients having vitamin-D-deficiency and insufficiency, and the difference was higher for the biointact than intact values. Negative correlation was detected between biointact parathyroid hormone and 25-hydroxivitamin-D in the hemodialysis group. Conclusions: Biointact parathyroid hormone levels better reflect the vitamin D supply and bone metabolism than intact levels, especially in hemodialysed patients. Orv. Hetil., 2013, 154(51), 2025–2036.


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