Dynamics and Sensitivity of Fractional-Order Delay Differential Model for Coronavirus (COVID-19) Infection

2021 ◽  
Vol 7 (7) ◽  
pp. 43-61
2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Angkhana Prommarat ◽  
Farida Chamchod

AbstractDeposition of lipid in the artery wall called atherosclerosis is recognized as a major cause of cardiovascular disease that leads to death worldwide. A better understanding into factors that may influence the delivery of gadolinium nanoparticles (Gd-NPs) that enhances quality of magnetic resonance imaging in diagnosis may provide a vital key for atherosclerotic treatment. In this study, we propose a delay differential model for describing the dynamics of Gd-NPs in bloodstream, peripheral arteries, and vasa vasorum with two phenomena of Gd-NPs during a sojourn in vasa vasorum. We then investigate the dynamical behaviors of Gd-NPs and explore the effects of sojourn time and transfer rates of Gd-NPs on the concentration of Gd-NPs in vasa vasorum at the 12th hour after the administration of gadolinium chelates contrast media and also the maximum concentration of Gd-NPs in peripheral arteries and vasa vasorum. Our results suggest that the sojourn of Gd-NPs in vasa vasorum may lead to complex behaviors of Gd-NPs dynamics, and transfer rates of Gd-NPs may have a significant impact on the concentration of Gd-NPs.


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Qiong Meng ◽  
Zhen Jin ◽  
Guirong Liu

AbstractThis paper studies the linear fractional-order delay differential equation $$ {}^{C}D^{\alpha }_{-}x(t)-px(t-\tau )= 0, $$ D − α C x ( t ) − p x ( t − τ ) = 0 , where $0<\alpha =\frac{\text{odd integer}}{\text{odd integer}}<1$ 0 < α = odd integer odd integer < 1 , $p, \tau >0$ p , τ > 0 , ${}^{C}D_{-}^{\alpha }x(t)=-\Gamma ^{-1}(1-\alpha )\int _{t}^{\infty }(s-t)^{- \alpha }x'(s)\,ds$ D − α C x ( t ) = − Γ − 1 ( 1 − α ) ∫ t ∞ ( s − t ) − α x ′ ( s ) d s . We obtain the conclusion that $$ p^{1/\alpha } \tau >\alpha /e $$ p 1 / α τ > α / e is a sufficient and necessary condition of the oscillations for all solutions of Eq. (*). At the same time, some sufficient conditions are obtained for the oscillations of multiple delays linear fractional differential equation. Several examples are given to illustrate our theorems.


Author(s):  
М.Г. Мажгихова

В работе доказана теорема существования и единственности решения краевой задачи со смещением для дифференциального уравнения дробного порядка с запаздывающим аргументом. Решение задачи выписано в терминах функции Грина. Получено условие однозначной разрешимости и показано, что оно может нарушаться только конечное число раз. In this paper we prove existence and uniqueness theorem to a boundary value problem with shift for a fractional order ordinary delay differential equation. The solution of the problem is written out in terms of the Green function. We find an explicit representation for solvability condition and show that it may only be violated a finite number of times


Mathematics ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 218 ◽  
Author(s):  
Muhammad Sher ◽  
Kamal Shah ◽  
Michal Fečkan ◽  
Rahmat Ali Khan

With the help of the topological degree theory in this manuscript, we develop qualitative theory for a class of multi-terms fractional order differential equations (FODEs) with proportional delay using the Caputo derivative. In the same line, we will also study various forms of Ulam stability results. To clarify our theocratical analysis, we provide three different pertinent examples.


Sign in / Sign up

Export Citation Format

Share Document