scholarly journals The diagnostic role of ascitic fluid adenosine deaminase activity in a peritoneal tuberculosis case presenting with abdominal pain and diarrhea

2021 ◽  
Author(s):  
Haluk MERGEN ◽  
Elif ERDEM ◽  
Harun AKAR
Keyword(s):  
Abdominal Pain ◽  
Adenosine Deaminase ◽  
Ascitic Fluid ◽  
Peritoneal Tuberculosis ◽  
Tuberculosis Case ◽  
Adenosine Deaminase Activity ◽  
Diagnostic Role

scholarly journals The value of adenosine deaminase (ADA) determination in the diagnosis of tuberculous ascites

1995 ◽  
Vol 37 (5) ◽  
pp. 449-453 ◽  
Author(s):  
Cesar Q. Brant ◽  
Mario R. Silva Jr. ◽  
Erica P. Macedo ◽  
Claudio Vasconcelos ◽  
Natalina Tamaki ◽  
...  
Keyword(s):  
Adenosine Deaminase ◽  
Ascitic Fluid ◽  
Spontaneous Bacterial Peritonitis ◽  
Malignant Ascites ◽  
Bacterial Peritonitis ◽  
Pancreatic Ascites ◽  
Adenosine Deaminase Activity ◽  
Sensitivity Specificity

In order to evaluate the role of the determination of adenosine deaminase activity (ADA) in ascitic fluid for the diagnosis of tuberculosis, 44 patients were studied. Based on biochemical, cytological, histopathological and microbiological tests, the patients were divided into 5 groups: G1 - tuberculous ascites (n = 8); G2 - malignant ascites (n = 13); G3 - spontaneous bacterial peritonitis (n = 6); G4 - pancreatic ascites (n = 2); G5 - miscelaneous ascites (n = 15). ADA concentration were significantly higher in G1 (133.50 ± 24.74 U/l) compared to the other groups (G2 = 41.85 ± 52.07 U/l; G3 = 10.63 ± 5.87 U/l; G4 = 18.00 ± 7.07 U/l; G5 = 11.23 ± 7.66 U/l). At a cut-off value of >31 U/l, the sensitivity, specificity and positive and negative preditive values were 100%, 92%, 72% and 100%, respectively. ADA concentrations as high as in tuberculous ascites were only found in two malignant ascites caused by lymphoma. We conclude that ADA determination in ascitic fluid is a useful and reliable screening test for diagnosing tuberculous ascites. Values of ADA higher than 31 U/l indicate more invasive methods to confirm the diagnosis of tuberculosis.

scholarly journals Reappraisal of the Role of Ascitic Fluid Adenosine Deaminase for the Diagnosis of Peritoneal Tuberculosis in Cirrhosis

2021 ◽  
Vol 78 (3) ◽  
pp. 168-176 ◽  
Author(s):  
Amol Sonyabapu Dahale ◽  
Amarender Singh Puri ◽  
Sanjeev Sachdeva ◽  
Anil K Agarwal ◽  
Ajay Kumar ◽  
...  
Keyword(s):  
Adenosine Deaminase ◽  
Ascitic Fluid ◽  
Peritoneal Tuberculosis

Abdominal pain and bowel dysfunction: diagnostic role of intestinal ultrasound

2001 ◽  
Vol 13 (8) ◽  
pp. 927-931 ◽  
Author(s):  
Marco Astegiano ◽  
Francesca Bresso ◽  
Teresa Cammarota ◽  
Antonino Sarno ◽  
Daniela Robotti ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Bowel Dysfunction ◽  
Diagnostic Role

Study of serum adenosine deaminase activity and c-reactive protein in patients of rheumatoid arthritis

2020 ◽  
Vol 11 (4) ◽  
pp. 7990-7993
Author(s):  
Sangeetha R ◽  
Ramesh Raju K A P ◽  
Hemapriya S ◽  
Suganthi V ◽  
Panneerselvam P
Keyword(s):  
Rheumatoid Arthritis ◽  
Adenosine Deaminase ◽  
Treatment Plan ◽  
Colorimetric Method ◽  
Disease Score ◽  
C Reactive Protein ◽  
Positive Correlation ◽  
Reactive Protein ◽  
Adenosine Deaminase Activity

Rheumatoid arthritis (RA) is a chronic disease that causes inflammatory synovitis. The treatment plan of RA includes reducing inflammation and improving the quality of life. Hence, understanding the role of Adenosine deaminase (ADA) and C-reactive protein helps for a better plan of treatment. The present study was undertaken to determine the serum ADA activity and CRP in RA patients and correlate with the severity of the progression of the disease. 25 patients diagnosed with RA as per 2010 ACR/EULAR criteria and 25 age and sex matched healthy controls were included in the study after informed consent. Blood samples were collected from all the subjects after an overnight fast, serum separated was analyzed immediately for Adenosine deaminase(ADA) activity measured using colorimetric method of Guisti and Galanti. Disease score, C-reactive protein, RA factor, ADA and ESR were significantly higher in cases when compared with controls. Significant positive correlation was present between the disease score and C-reactive protein, RA factor among cases. A positive correlation was observed between the disease score and ADA, but it was not statistically significant among cases.

The Diagnostic Role of Bacterial DNA in Ascitic Fluid Infection in Patients with Cirrhotic Ascites

2017 ◽  
Vol 26 (1) ◽  
pp. 121-127
Author(s):  
Mohammed A. Saleh ◽  
Eman M. El-Sehsah ◽  
Ashraf A. Beheiry
Keyword(s):  
Ascitic Fluid ◽  
Bacterial Dna ◽  
Diagnostic Role

scholarly journals Ascitic fluid gamma interferon concentrations and adenosine deaminase activity in tuberculous peritonitis.

Gut ◽  
1995 ◽  
Vol 36 (3) ◽  
pp. 419-421 ◽  
Author(s):  
M A Sathar ◽  
A E Simjee ◽  
Y M Coovadia ◽  
P N Soni ◽  
S A Moola ◽  
...  
Keyword(s):  
Adenosine Deaminase ◽  
Ascitic Fluid ◽  
Gamma Interferon ◽  
Tuberculous Peritonitis ◽  
Adenosine Deaminase Activity

Adenosine deaminase (ADA) in peritoneal tuberculosis: Diagnostic value in ascitic fluid and serum

Tubercle ◽  
1990 ◽  
Vol 71 (2) ◽  
pp. 121-126 ◽  
Author(s):  
D.K. Bhargava ◽  
M. Gupta ◽  
S. Nijhawan ◽  
S. Dasarathy ◽  
A.K.S. Kushwaha
Keyword(s):  
Adenosine Deaminase ◽  
Ascitic Fluid ◽  
Diagnostic Value ◽  
Peritoneal Tuberculosis

scholarly journals Role of diagnostic laparoscopy in chronic abdominal pain

2019 ◽  
Vol 7 (1) ◽  
pp. 217
Author(s):  
Sajid Hussain ◽  
Safia Haideri
Keyword(s):  
Abdominal Pain ◽  
Diagnostic Laparoscopy ◽  
Chronic Abdominal Pain ◽  
Prospective Longitudinal Study ◽  
Medical College ◽  
Therapeutic Value ◽  
Diagnostic Role ◽  
Surgery Department ◽  
Prospective Longitudinal

Background: Chronic abdominal pain is a common disorder both in general practice and in hospitals. Although patients with this type of pain may have undergone numerous diagnostic workups, including surgery, their pain remains a challenge to all known diagnostic and treatment methods. Laparoscopy can identify abnormal findings and improve the outcome in patients with chronic abdominal pain, as it allows surgeons to see and treat many abdominal conditions that cannot be diagnosed otherwise.Methods: A prospective longitudinal study was conducted from August 2016 to September 2017 in the Surgery Department of Vinayaka Missions Kirupananda Variyar Medical College, Salem. 50 patients with abdominal pain for 3 months and above were included in the study. Detailed history was recorded from patients and thorough clinical examination was performed. The findings were recorded in the proforma.Results: The most common laparoscopy finding among the study subjects was dense adhesions (26%) followed by abdominal TB (18%) and mesenteric lymphadenopathy (16%). 88% of the study subjects had a total relief of their abdominal pain and 6% of the patients felt that the pain was reduced and for the remaining 6% the pain was still persistent.Conclusions: The efficacy of diagnostic laparoscopy was 90% in the current study. Laparoscopy has an effective diagnostic role in evaluating patients with chronic abdominal pain, in whom conventional methods of investigations have failed to elicit a certain cause. The therapeutic value of diagnostic laparoscopy is also accepted, well-appreciated, and it cannot be underestimated.

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