scholarly journals Method for Controlling Intracellular Protein Activity Using Photoresponsive Nanoparticles

2021 ◽  
Vol 34 (x) ◽  
pp. 1
Author(s):  
Shuhei Murayama ◽  
Noriaki Kono ◽  
Takashi Takaki ◽  
Masaru Kato
Keyword(s):  
Intracellular Protein ◽  
Protein Activity

scholarly journals Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer

Cell ◽  
2020 ◽  
Vol 182 (4) ◽  
pp. 872-885.e19 ◽  
Author(s):  
Yonatan Katzenelenbogen ◽  
Fadi Sheban ◽  
Adam Yalin ◽  
Ido Yofe ◽  
Dmitry Svetlichnyy ◽  
...  
Keyword(s):  
Intracellular Protein ◽  
Protein Activity

Non-Covalent Carrier Hydrophobicity as a Universal Predictor of Intracellular Protein Activity

2021 ◽  
Author(s):  
Christopher R. Hango ◽  
Coralie M. Backlund ◽  
Hazel C. Davis ◽  
Nicholas D. Posey ◽  
Lisa M. Minter ◽  
...  
Keyword(s):  
Intracellular Protein ◽  
Protein Activity

Androgen-induced plasticity at a “vocal” neuromuscular synapse

1994 ◽  
Vol 52 ◽  
pp. 32-33
Author(s):  
Darcy B. Kelley ◽  
Martha L. Tobias ◽  
Mark Ellisman
Keyword(s):  
Xenopus Laevis ◽  
Motor Neurons ◽  
Sexual Differentiation ◽  
Molecular Basis ◽  
Neuromuscular Synapse ◽  
Sexually Dimorphic ◽  
Intracellular Protein ◽  
Developmental Program ◽  
Androgen Action ◽  
Clawed Frog

Brain and muscle are sexually differentiated tissues in which masculinization is controlled by the secretion of androgens from the testes. Sensitivity to androgen is conferred by the expression of an intracellular protein, the androgen receptor. A central problem of sexual differentiation is thus to understand the cellular and molecular basis of androgen action. We do not understand how hormone occupancy of a receptor translates into an alteration in the developmental program of the target cell. Our studies on sexual differentiation of brain and muscle in Xenopus laevis are designed to explore the molecular basis of androgen induced sexual differentiation by examining how this hormone controls the masculinization of brain and muscle targets.Our approach to this problem has focused on a highly androgen sensitive, sexually dimorphic neuromuscular system: laryngeal muscles and motor neurons of the clawed frog, Xenopus laevis. We have been studying sex differences at a synapse, the laryngeal neuromuscular junction, which mediates sexually dimorphic vocal behavior in Xenopus laevis frogs.

Sign in / Sign up

Export Citation Format

Share Document