scholarly journals Redox-active Monolayers Deposited on Gold Electrode Surface–Universal Platforms for Electrochemical Sensing

2020 ◽  
Vol 32 (3) ◽  
pp. 1065
Author(s):  
Jerzy Radecki ◽  
Hanna Radecka
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Electrochemical Sensing ◽  
Redox Active

scholarly journals Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing

2020 ◽  
Author(s):  
Hanie Yousefi ◽  
alam mahmud ◽  
Dingran Chang ◽  
Jagotamoy Das ◽  
Surath Gomis ◽  
...  
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Direct Analysis ◽  
Electrochemical Sensing ◽  
New Method ◽  
Spike Protein ◽  
Positive Potential ◽  
Molecular Sensor ◽  
Viral Particles ◽  
Kinetics Of

This manuscript describes a new method that enables direct analysis of viral particles in unprocessed samples.Using an electrochemical readout method that requires no external reagents, we detect the SARS-CoV-2 virus in the saliva of infected patients.The approach relies on a molecular sensor tethered to the surface of a gold electrode that contains an antibody, specific to the targetof interest, which here is the SARS-CoV-2 S1 spike protein that is displayed on the viral capsule. The antibody is attached to the electrode using a negatively charged linker that is composed of DNA. When a positive potential is applied to the electrode, the sensor complex is attracted to the electrode surface. The kinetics of transport is measured using chronoamperometry and readout is possible based on the absense or precense of virus and its effect on the complex movevment on electrode surface.

scholarly journals Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing

2020 ◽  
Author(s):  
Hanie Yousefi ◽  
alam mahmud ◽  
Dingran Chang ◽  
Jagotamoy Das ◽  
Surath Gomis ◽  
...  
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Direct Analysis ◽  
Electrochemical Sensing ◽  
New Method ◽  
Spike Protein ◽  
Positive Potential ◽  
Molecular Sensor ◽  
Viral Particles ◽  
Kinetics Of

This manuscript describes a new method that enables direct analysis of viral particles in unprocessed samples.Using an electrochemical readout method that requires no external reagents, we detect the SARS-CoV-2 virus in the saliva of infected patients.The approach relies on a molecular sensor tethered to the surface of a gold electrode that contains an antibody, specific to the targetof interest, which here is the SARS-CoV-2 S1 spike protein that is displayed on the viral capsule. The antibody is attached to the electrode using a negatively charged linker that is composed of DNA. When a positive potential is applied to the electrode, the sensor complex is attracted to the electrode surface. The kinetics of transport is measured using chronoamperometry and readout is possible based on the absense or precense of virus and its effect on the complex movevment on electrode surface.

scholarly journals Detection of SARS-CoV-2 Viral Particles using Direct, Reagent-Free Electrochemical Sensing

2020 ◽  
Author(s):  
Hanie Yousefi ◽  
alam mahmud ◽  
Dingran Chang ◽  
Jagotamoy Das ◽  
Surath Gomis ◽  
...  
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Direct Analysis ◽  
Electrochemical Sensing ◽  
New Method ◽  
Spike Protein ◽  
Positive Potential ◽  
Molecular Sensor ◽  
Viral Particles ◽  
Kinetics Of

This manuscript describes a new method that enables direct analysis of viral particles in unprocessed samples.Using an electrochemical readout method that requires no external reagents, we detect the SARS-CoV-2 virus in the saliva of infected patients.The approach relies on a molecular sensor tethered to the surface of a gold electrode that contains an antibody, specific to the targetof interest, which here is the SARS-CoV-2 S1 spike protein that is displayed on the viral capsule. The antibody is attached to the electrode using a negatively charged linker that is composed of DNA. When a positive potential is applied to the electrode, the sensor complex is attracted to the electrode surface. The kinetics of transport is measured using chronoamperometry and readout is possible based on the absense or precense of virus and its effect on the complex movevment on electrode surface.

scholarly journals Detection of SARS-CoV-2 Viral Particles using Direct, Reagent-Free Electrochemical Sensing

2020 ◽  
Author(s):  
Hanie Yousefi ◽  
alam mahmud ◽  
Dingran Chang ◽  
Jagotamoy Das ◽  
Surath Gomis ◽  
...  
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Direct Analysis ◽  
Electrochemical Sensing ◽  
New Method ◽  
Spike Protein ◽  
Positive Potential ◽  
Molecular Sensor ◽  
Viral Particles ◽  
Kinetics Of

This manuscript describes a new method that enables direct analysis of viral particles in unprocessed samples.Using an electrochemical readout method that requires no external reagents, we detect the SARS-CoV-2 virus in the saliva of infected patients.The approach relies on a molecular sensor tethered to the surface of a gold electrode that contains an antibody, specific to the targetof interest, which here is the SARS-CoV-2 S1 spike protein that is displayed on the viral capsule. The antibody is attached to the electrode using a negatively charged linker that is composed of DNA. When a positive potential is applied to the electrode, the sensor complex is attracted to the electrode surface. The kinetics of transport is measured using chronoamperometry and readout is possible based on the absense or precense of virus and its effect on the complex movevment on electrode surface.

Electrochemical detection of adenine and guanine using a self-assembled copper(ii)–thiophenyl-azo-imidazole complex monolayer modified gold electrode

RSC Advances ◽  
2014 ◽  
Vol 4 (91) ◽  
pp. 49819-49826 ◽  
Author(s):  
Koushik Barman ◽  
Sk Jasimuddin
Keyword(s):  
Electrochemical Detection ◽  
Gold Electrode ◽  
Electrochemical Sensing ◽  
Self Assembled

A self-assembled copper(ii)–thiophenyl-azo-imidazole complex monolayer modified gold electrode exhibits an excellent electrochemical sensing ability towards adenine and guanine at physiological pH.

scholarly journals Kinetic studies of HRP adsorption on ds-DNA immobilized on gold electrode surface by EIS and SPR

2010 ◽  
Vol 21 (9) ◽  
pp. 1648-1655 ◽  
Author(s):  
Danielle C. M Ferreira ◽  
Renata K Mendes ◽  
Lauro T Kubota
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Kinetic Studies

Effect of surfactants and halide ions on the adsorption and oxidation of homocysteine at the gold electrode

RSC Advances ◽  
2016 ◽  
Vol 6 (55) ◽  
pp. 50315-50321
Author(s):  
Jianying Wang ◽  
Shangshang Zuo ◽  
Cui Lu ◽  
Yanbing Zu ◽  
Zuofeng Chen
Keyword(s):  
Electrode Surface ◽  
Gold Electrode ◽  
Halide Ions

This study demonstrates how adsorptive species including a series of surfactants and halide ions affect the adsorption of Hcy on the electrode surface, as well as how the change of Hcy adsorption affects the oxidation of Hcy.

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