scholarly journals Association between Coronary Artery Disease and Erectile Dysfunction in Patients of a University Hospital

2017 ◽  
Vol 3 (07) ◽  
pp. 40-44
Author(s):  
Fernando Nestor Fácio Júnior ◽  
Nicole Favretto Baltazar ◽  
Carolina Dario Fischer ◽  
Stefanie Basilio Medeiros ◽  
Paola Beatriz Souza Ferrés ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Erectile Dysfunction ◽  
Coronary Artery ◽  
University Hospital ◽  
Artery Disease

scholarly journals Purchases of medical therapy recommended for coronary artery disease before and after elective revascularisation

2019 ◽  
Vol 76 (1) ◽  
pp. 81-88
Author(s):  
Jari Heiskanen ◽  
Juha Hartikainen ◽  
Janne Martikainen ◽  
Heikki Miettinen ◽  
Mikko Hippeläinen ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Medical Therapy ◽  
Coronary Bypass ◽  
University Hospital ◽  
Blocking Agents ◽  
Before And After ◽  
Artery Disease ◽  
Long Acting ◽  
Cabg Patients

Abstract Aims We studied the purchases of medical therapy recommended for coronary artery disease patients before and after elective revascularisation (percutaneous coronary intervention (PCI) or coronary bypass grafting (CABG)). Methods All patients who underwent an elective PCI (N = 1557) or CABG (N = 1768) at the Heart Center, Kuopio University hospital between 2007 and 2014 were included. Data were collected from the hospital’s coronary register and national registers, and obtained for 3 years before and 1 year after the revascularisation. Results Altogether 85.2% of PCI patients and 88.1% of CABG patients had purchased lipid-modifying agents before the procedure, and 94.9% and 96.8% during the post-procedure follow-up year, respectively. Beta-blocking agents were purchased by 84.9% of PCI patients before and by 87.9% after the procedure and by 86.3% of CABG patients before and 97.1% after the operation. Of PCI patients, 64.3% had purchased organic long-acting nitrates before the procedure and 54.4% also after the procedure. Among CABG patients, the purchase of organic long-acting nitrates fell from 59.7% before to 10.1% after the operation. The use of ADP receptor blocking agents increased in PCI patients (26.3 to 83.9%) and the use of warfarin in CABG patients (9.4 to 21.3%). Medication purchases were more common among those who had greater use of hospital services before and after the procedures. Conclusions In both PCI and CABG patients, the use of medical therapy before and after revascularisation procedure complied with current guidelines. Purchases of long-acting nitrates were common in the PCI group even after the procedure.

P6262Coronary microphysiology in relation to low endogenous testosterone and dietary habits in andropause men with erectile dysfunction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Angelis ◽  
N loakeimidis ◽  
Y Dimitroglou ◽  
K Zisimos ◽  
C Georgakopoulos ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Erectile Dysfunction ◽  
Coronary Artery ◽  
Pulse Wave ◽  
Dietary Habits ◽  
Linear Regression Analysis ◽  
Male Hypogonadism ◽  
Middle Aged ◽  
Flow Reserve ◽  
Artery Disease

Abstract Background Coronary flow reserve (CFR) in the presence of non-obstructive coronary artery disease displays the ability of microcirculation to augment flow to the myocardium. Endogenous total testosterone (TT) exhibits vasodilator effects and the Mediterranean diet (Med-diet) promotes cardiovascular health. Erectile dysfunction (ED) in a milieu of subclinical microvascular damage often coexists with the decline of endogenous testosterone of the aging male population. Purpose To investigate the effects of male hypogonadism in CFR and the relation between the Med-diet and the TT of the andropause middle aged men with ED. Methods 190 non-diabetic male patients with ED (mean age: 56yo) enrolled the study. Significant epicardial coronary artery disease was excluded after a negative for ischemia dobutamine stress echo test. We measured the CFR of the left anterior descending artery by performing an adenosine protocol (maximum dose 140μg/kg/min over 6 minutes). Measurements by the pulse wave Doppler were achieved at the middle/distal LAD segment under the guidance of color Doppler flow mapping. CFR was estimated as ratio between peak diastolic flow velocity following drug infusion and rest. CFR ratio ≥2 is considered as non-ischemic response and higher values indicate microvascular coronary integrity. TT was measured in all patients on blood samples taken before 09:00 am and hypogonadism was considered when TT <3,5 ng/ml. ED severity and adherence to the Med-diet were assessed by the SHIM-5 (range: 0–25) and the Med-diet (range: 0–55) scores. Higher values point to better erectile function and a great Med-diet compliance respectively. Finally, carotid – femoral pulse wave velocity (PWV) was assessed as index of central vascular stiffness (sphygmocor device). Results In bivariate analysis CFR ratio (mean value: 2,35) was positively related to TT (p<0,001, r=0,9), the SHIM-5 and the Med-diet score (p<0,05 for both r=0,45 and r=0,5 respectively).On the contrary, it was negatively related to the PWV (p<0,05, r=−0,35). Med-diet was related to the SHIM-5 score (p=0,01, r=0,363) and to TT (p=0,02, r=0,46). In multiple linear regression analysis relation of CFR to TT remain significant (p<0,01) after adjustment for age, body mass index (BMI), LDL, PWV, smoking habits and systolic blood pressure. We further stratified our population in to hypogonadics (HYPO, n=38, 20%) and patients with normal TT levels. Poor adherence to the Med-diet was the only factor related to hypogonadism (independent sample t-test p=0,005) as compared with age, BMI and smoking. Conclusion In middle aged men with ED endogenous testosterone enhances coronary microcirculation. Moreover the Med-diet regime may blunt the fall of androgens during andropause independently of other life-style parameters. We emphasize on this culinary preference to assist coronary microvascular physiology and maintain hormonal balance.

Erectile dysfunction can improve the effectiveness of the current guidelines for the screening for asymptomatic coronary artery disease in diabetes

Endocrine ◽  
2011 ◽  
Vol 40 (2) ◽  
pp. 273-279 ◽  
Author(s):  
Carmine Gazzaruso ◽  
Adriana Coppola ◽  
Tiziana Montalcini ◽  
Cinzia Valenti ◽  
Adriana Garzaniti ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Erectile Dysfunction ◽  
Coronary Artery ◽  
Artery Disease ◽  
Asymptomatic Coronary Artery Disease ◽  
Current Guidelines

Erectile Dysfunction and Coronary Artery Disease: An Association of Higher Risk in Younger Men

2011 ◽  
Vol 8 (5) ◽  
pp. 1445-1453 ◽  
Author(s):  
Charles E. Riedner ◽  
Ernani L. Rhoden ◽  
Sandra C. Fuchs ◽  
Marco V. Wainstein ◽  
Sandro C. Gonçalves ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Erectile Dysfunction ◽  
Coronary Artery ◽  
Younger Men ◽  
Artery Disease
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