scholarly journals Validation of an RPE-based submaximal oxygen consumption test using a total body recumbent stepper for individuals with spinal cord injury : a proof of concept study.

2013 ◽  
Author(s):  
John McCulloch
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Oxygen Consumption ◽  
Proof Of Concept ◽  
Concept Study ◽  
Cord Injury ◽  
Total Body

scholarly journals Cardiorespiratory Responses to 10 Weeks of Exoskeleton-Assisted Overground Walking Training inChronic Nonambulatory Patients with Spinal Cord Injury

Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5022
Author(s):  
Jae Hyeon Park ◽  
Hyeon Seong Kim ◽  
Seong Ho Jang ◽  
Dong Jin Hyun ◽  
Sang In Park ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Oxygen Consumption ◽  
Exercise Intensity ◽  
Moderate Physical Activity ◽  
Intensity Level ◽  
Cardiorespiratory System ◽  
Cardiorespiratory Responses ◽  
Cord Injury ◽  
Walking Efficiency

Exercise intensity of exoskeleton-assisted walking in patients with spinal cord injury (SCI) has been reported as moderate. However, the cardiorespiratory responses to long-term exoskeleton-assisted walking have not been sufficiently investigated. We investigated the cardiorespiratory responses to 10 weeks of exoskeleton-assisted walking training in patients with SCI. Chronic nonambulatory patients with SCI were recruited from an outpatient clinic. Walking training with an exoskeleton was conducted three times per week for 10 weeks. Oxygen consumption and heart rate (HR) were measured during a 6-min walking test at pre-, mid-, and post-training. Exercise intensity was determined according to the metabolic equivalent of tasks (METs) for SCI and HR relative to the HR reserve (%HRR). Walking efficiency was calculated as oxygen consumption divided by walking speed. The exercise intensity according to the METs (both peak and average) corresponded to moderate physical activity and did not change after training. The %HRR demonstrated a moderate (peak %HRR) and light (average %HRR) exercise intensity level, and the average %HRR significantly decreased at post-training compared with mid-training (31.6 ± 8.9% to 24.3 ± 7.3%, p = 0.013). Walking efficiency progressively improved after training. Walking with an exoskeleton for 10 weeks may affect the cardiorespiratory system in chronic patients with SCI.

scholarly journals Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration

2016 ◽  
Vol 41 (1-2) ◽  
pp. 431-449 ◽  
Author(s):  
Warin Krityakiarana ◽  
Paul M. Zhao ◽  
Kevin Nguyen ◽  
Fernando Gomez-Pinilla ◽  
Naiphinich Kotchabhakdi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Trophic Factors ◽  
Proof Of Concept ◽  
Cord Injury

scholarly journals Detraining from total body exercise ergometry in individuals with spinal cord injury

Spinal Cord ◽  
1998 ◽  
Vol 36 (11) ◽  
pp. 782-789 ◽  
Author(s):  
Alfred Burke Gurney ◽  
Robert A Robergs ◽  
J Aisenbrey ◽  
J C Cordova ◽  
L McClanahan
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cord Injury ◽  
Total Body

scholarly journals Erratum to: Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration

2016 ◽  
Vol 41 (7) ◽  
pp. 1844-1844
Author(s):  
Warin Krityakiarana ◽  
Paul M. Zhao ◽  
Kevin Nguyen ◽  
Fernando Gomez-Pinilla ◽  
Naiphinich Kotchabhakdi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Trophic Factors ◽  
Proof Of Concept ◽  
Cord Injury

scholarly journals Protocol for rapid onset of mobilisation in patients with traumatic spinal cord injury (PROMPT-SCI) study: a single-arm proof-of-concept trial of early in-bed leg cycling following acute traumatic spinal cord injury

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e049884
Author(s):  
Jean-Marc Mac-Thiong ◽  
Andreane Richard-Denis ◽  
Yvan Petit ◽  
Francis Bernard ◽  
Dorothy Barthélemy ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Patient Outcomes ◽  
Spinal Surgery ◽  
Rapid Onset ◽  
Traumatic Spinal Cord Injury ◽  
Proof Of Concept ◽  
Historical Cohort ◽  
Cord Injury ◽  
Leg Cycling

IntroductionActivity-based therapy (ABT) is an important aspect of rehabilitation following traumatic spinal cord injury (SCI). Unfortunately, it has never been adapted to acute care despite compelling preclinical evidence showing that it is safe and effective for promoting neurological recovery when started within days after SCI. This article provides the protocol for a study that will determine the feasibility and explore potential benefits of early ABT in the form of in-bed leg cycling initiated within 48 hours after the end of spinal surgery for SCI.Methods and analysisPROMPT-SCI (protocol for rapid onset of mobilisation in patients with traumatic SCI) is a single-site single-arm proof-of-concept trial. Forty-five patients aged 18 years or older with a severe traumatic SCI (American Spinal Injury Association Impairment Scale grade A, B or C) from C0 to L2 undergoing spinal surgery within 48 hours of the injury will be included. Participants will receive daily 30 min continuous sessions of in-bed leg cycling for 14 consecutive days, initiated within 48 hours of the end of spinal surgery. The feasibility outcomes are: (1) absence of serious adverse events associated with cycling, (2) completion of 1 full session within 48 hours of spinal surgery for 90% of participants and (3) completion of 11 sessions for 80% of participants. Patient outcomes 6 weeks and 6 months after the injury will be measured using neurofunctional assessments, quality of life questionnaires and inpatient length of stay. Feasibility and patient outcomes will be analysed with descriptive statistics. Patient outcomes will also be compared with a matched historical cohort that has not undergone in-bed cycling using McNemar and Student’s t-tests for binary and continuous outcomes, respectively.Ethics and disseminationPROMPT-SCI is approved by the Research Ethics Board of the CIUSSS NIM. Recruitment began in April 2021. Dissemination strategies include publications in scientific journals and presentations at conferences.Trial registration numberNCT04699474.

Planned Staged Repair of Thoracoabdominal Aortic Aneurysms to Minimize Spinal Cord Injury: A Proof of Concept

Aorta ◽  
2016 ◽  
Vol 3 (5) ◽  
pp. 177-180 ◽  
Author(s):  
Gabriele Di Luozzo ◽  
Michael Wilderman ◽  
Amit Pawale ◽  
Jock McCullough ◽  
Randall B. Griepp
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Aortic Aneurysms ◽  
Proof Of Concept ◽  
Cord Injury
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