scholarly journals Necrotising fasciitis—A rare complication of split-thickness skin graft donor area

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Rahul Bamal ◽  
Rakesh Kain

<p class="Default">Split-thickness skin grafting (STSG) is commonly used to cover raw areas of various aetiologies. Donor sites are known to get infected sometimes, but necrotising fasciitis is not often reported. We report here a case of donor-site necrotising fasciitis and its successful management. There is a need for surgeons to stay vigilant for this rare but probable complication of skin grafting.</p>

Author(s):  
Catherine M Legemate ◽  
Ymke Lucas ◽  
Irma M M H Oen ◽  
Cornelis H Van Der Vlies

Abstract Split-thickness skin grafting remains a fundamental treatment for patients with deep burns and other traumatic injuries. Unfortunately, the donor site wound that remains after split skin graft (SSG) harvesting may also cause problems for the patient; they can lead to discomfort and scars with a poor cosmetic outcome. Regrafting of the donor site is one of the methods described to improve donor site healing and scarring. In this report, we describe a case of a 26-year-old woman with a self-inflicted chemical burn (0.5% TBSA) who underwent split skin grafting. During surgery, only part of the donor site was regrafted with split skin graft remnants. This part healed faster and had a better scar quality at 3 months postsurgery. Nevertheless, the appearance and patients’ opinion on the regrafted part deteriorated after 12 months. With this case report, we aim to create awareness of the long-term consequences of regrafting, which may differ from short-time results. Patients expected to have poor reepithelialization potential may benefit from regrafting of the SSG on the donor site. But in healthy young individuals, timewise there would be no benefit since it can lead to an aesthetically displeasing result.


Burns ◽  
2021 ◽  
Author(s):  
Malachy Asuku ◽  
Tzy-Chyi Yu ◽  
Qi Yan ◽  
Elaine Böing ◽  
Helen Hahn ◽  
...  

2003 ◽  
Vol 29 (2) ◽  
pp. 168-172
Author(s):  
AYKUT MISIRLIOGLU ◽  
SINEM EROGLU ◽  
NACI KARACAOGLAN ◽  
MITHAT AKAN ◽  
TAYFUN AKOZ ◽  
...  

2019 ◽  
Vol 12 (9) ◽  
pp. e231295 ◽  
Author(s):  
Lisa Scupham ◽  
Atul Ingle

The case report discusses split thickness skin grafting in a patient with active psoriasis. This also reports a case of a rare variant of squamous cell carcinoma.


2017 ◽  
Vol 5 (5) ◽  
pp. e1339 ◽  
Author(s):  
Brian P. Bradow ◽  
Geoffrey G. Hallock ◽  
Samuel P. Wilcock

Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Alexandra Poinas ◽  
Pierre Perrot ◽  
Judith Lorant ◽  
Olivier Nerrière ◽  
Jean-Michel Nguyen ◽  
...  

Abstract Background Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dressings, releasing growth factors, cytokines and extracellular matrix components essential for proper wound healing. However, they are susceptible to immune rejection and this is their major weakness. Thanks to their low immunogenicity and high effectiveness in regeneration, fetal skin cells represent an attractive alternative to the commonly used autologous and allogeneic skin grafts. Methods/design We developed a new dressing comprising a collagen matrix seeded with a specific ratio of active fetal fibroblasts and keratinocytes. These produce a variety of healing growth factors and cytokines which will increase the speed of wound healing and induce an immunotolerant state, with a slight inflammatory reaction and a reduction in pain. The objective of this study is to demonstrate that the use of this biological dressing for wound healing at the split-thickness skin graft (STSG) donor site, reduces the time to healing, decreases other co-morbidities, such as pain, and improves the appearance of the scar. This investigation will be conducted as part of a randomized study comparing our new biological dressing with a conventional treatment in a single patient, thus avoiding the factors that may influence the healing of a graft donor site. Discussion This clinical trial should enable the development of a new strategy for STSG donor-wound healing based on a regenerative dressing. The pain experienced in the first few days of STSG healing is well known due to the exposure of sensory nerve endings. Reducing this pain will also reduce analgesic drug intake and the duration of sick leave. Our biological dressing will meet the essential need of surgeons to “re-crop” from existing donor sites, e.g., for thermal-burn patients. By accelerating healing, improving the appearance of the scar and reducing pain, we hope to improve the conditions of treatment for skin grafts. Trial registration ClinicalTrials.gov, ID: NCT03334656. Registered on 7 November 2017.


2013 ◽  
Vol 34 (2) ◽  
pp. e80-e86 ◽  
Author(s):  
Sigrid Blome-Eberwein ◽  
Michael Abboud ◽  
Daniel D. Lozano ◽  
Rohit Sharma ◽  
Sherrine Eid ◽  
...  

Burns ◽  
2008 ◽  
Vol 34 (7) ◽  
pp. 1011-1014 ◽  
Author(s):  
Fatih Uygur ◽  
Rahmi Evınc ◽  
Ersin Ulkur ◽  
Bahattin Celıkoz

1974 ◽  
Vol 14 (2) ◽  
pp. 163-167 ◽  
Author(s):  
GARY D. FRIEDMAN ◽  
ANGELO CAPOZZI ◽  
VINCENT R. PENNISI

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