Respiratory and Motion Artefacts Removal from ICG Signal Using Denoising Techniques for Hemodynamic Parameters Monitoring

Myocardial ischemia is the consequence of an unbalance between coronary flow that can be achieved and myocardial metabolic needs. Pathological state of both epicardial and intramyocardial vessels may be responsible for inducing ischemia. However, revascularization decision should be based on the severity of each epicardial lesion that is evaluated. There are different diagnostic tools that may help for the evaluation of each compartment which is based on the measurement of coronary hemodynamics. Pressure-derived indices are recommended by current guidelines for evaluation of epicardial stenosis significance. We assess the complex interaction between hemodynamic parameters in order to understand how different parameters are influenced in the settings of microvascular dysfunction.

Download Full-text

A longitudinal study of a lateral intracranial aneurysm: identifying the hemodynamic parameters behind its inception and growth using computational fluid dynamics

Journal of the Brazilian Society of Mechanical Sciences and Engineering ◽

10.1007/s40430-021-02836-6 ◽

2021 ◽

Vol 43 (3) ◽

Author(s):

I. L. Oliveira ◽

G. B. Santos ◽

J. Militzer ◽

C. E. Baccin ◽

R. T. Tatit ◽

...

Keyword(s):

Fluid Dynamics ◽

Computational Fluid Dynamics ◽

Longitudinal Study ◽

Intracranial Aneurysm ◽

Hemodynamic Parameters

Download Full-text

Circulating nerve growth factor receptor positive cells are associated with severity and prognosis of pulmonary arterial hypertension

Pulmonary Circulation ◽

10.1177/2045894021990525 ◽

2021 ◽

Vol 11 (1) ◽

pp. 204589402199052

Author(s):

Chiaki Goten ◽

Soichiro Usui ◽

Shin-ichiro Takashima ◽

Oto Inoue ◽

Hirofumi Okada ◽

...

Keyword(s):

Nerve Growth Factor ◽

Growth Factor ◽

Pulmonary Arterial Hypertension ◽

Arterial Hypertension ◽

Growth Factor Receptor ◽

Nerve Growth Factor Receptor ◽

Clinical Severity ◽

Hemodynamic Parameters ◽

Nerve Growth ◽

Pulmonary Arterial

Pulmonary arterial hypertension (PAH) remains a disease with a poor prognosis, so early detection and treatment are very important. Sensitive and non-invasive markers for PAH are urgently required. This study was performed to identify sensitive markers of the clinical severity and prognosis of PAH. Patients diagnosed with PAH (n = 30) and control participants (n = 15) were enrolled in this observational study. Major EPC and MSC markers (including CD34, CD133, VEGFR2, CD90, PDGFRα, and NGFR) in peripheral blood mononuclear cells (PBMNCs) were assessed by flow cytometry. Associations of these markers with hemodynamic parameters (e.g. mean pulmonary arterial pressure, pulmonary vascular resistance, and cardiac index) were assessed. Patients with PAH were followed up for 12 months to assess the incidence of major adverse events, defined as death or lung transplantation. Levels of circulating EPC and MSC markers in PBMNCs were higher in patients with PAH than in control participants. Among the studied markers, nerve growth factor receptor (NGFR) was significantly positively correlated with hemodynamic parameters. During the 12-month follow-up period, major-event-free survival was significantly higher in patients with PAH who had relatively low frequencies of NGFR positive cells than patients who had higher frequencies. These results suggested that the presence of circulating NGFR positive cells among PBMNCs may be a novel biomarker for the severity and prognosis of PAH.

Download Full-text

Anesthesia for Transoral Endoscopic Parathyroidectomy by Vestibular Approach (TOEPVA)

Ain-Shams Journal of Anesthesiology ◽

10.1186/s42077-021-00160-8 ◽

2021 ◽

Vol 13 (1) ◽

Author(s):

Fulya YILMAZ ◽

Koray BAS

Keyword(s):

Demographic Data ◽

Surgical Techniques ◽

Hemodynamic Parameters ◽

Safe Anesthesia ◽

Close Cooperation ◽

Improve Patient Management ◽

Conventional Open Surgery ◽

Vestibular Approach ◽

Improve Patient ◽

Endoscopic Parathyroidectomy

Abstract Background After thyroid diseases, hyperparathyroidism is one of the most common endocrine surgical diseases. The increasing diagnosis of thyroid pathologies in early stages and a societal emphasis on physical appearances, especially in young women, have led to the development of new surgical techniques alternative to conventional transcervical incision consistently. Here, we describe our anesthesia experience for parathyroidectomy with Transoral Endoscopic Parathyroidectomy by Vestibular Approach (TOEPVA). Patients who undergo TOEPVA at our institution between November 2018 and April 2019 were reviewed. Demographic data and hemodynamic parameters were reported. Results Seven patients were operated successfully by this technique, none of which required conversion to conventional open surgery. Two patients required atropine and one patient required ephedrine during insufflation. Conclusion After induction of anesthesia with propofol, remifentanil, and rocuronium and anesthesia managed by desflurane co-administered with continuous infusion of remifentanil provide feasible and safe anesthesia for TOEPVA. However, especially during hydrodissection and insufflation, a close cooperation between surgeon and anesthetist has a great value to improve patient management.

Download Full-text