scholarly journals A Co Op Based International Engineering Minor Degree

2020 ◽  
Author(s):  
Gary R. Martin
Keyword(s):  
Minor Degree

Platelet Incorporation of Labelled Adenosine and Adenosine Diphosphate

1969 ◽  
Vol 22 (02) ◽  
pp. 304-315 ◽  
Author(s):  
E. W Salzman ◽  
T. P Ashford ◽  
D. A Chambers ◽  
Lena L. Neri
Keyword(s):  
Platelet Rich Plasma ◽  
Adenosine Diphosphate ◽  
Platelet Inhibition ◽  
Electron Microscopic ◽  
Platelet Binding ◽  
Minor Degree ◽  
A Minor ◽  
Plasma Marker ◽  
Electron Microscopic Radioautography ◽  
Simultaneous Assessment

SummaryAfter incubation of platelet-rich plasma with labelled adenosine or ADP, platelet incorporation of radioactivity was assessed. Platelets were rapidly separated for counting by filtration through cellulose acetate Millipore. Inulin-H3 served as a plasma marker, and triple isotope techniques permitted simultaneous assessment of the behavior of the adenine and phosphate moieties of ADP without washing of platelets. In other experiments, electron microscopic radioautography was employed to trace the label after platelet incorporation.The results were consistent with previous reports that ADP is dephosphorylated in plasma and is incorporated by platelets only as a dephosphorylated residue, probably adenosine. The label crossed the platelet membrane and entered the platelet, where it was distributed in platelet granules and the agranular cell sap. Concentration within granules occurred to a minor degree.The results support the hypothesis that platelet aggregation by ADP occurs without a persistent bond of ADP to the platelet. Inhibition of aggregation by adenosine probably depends on a metabolic or transport process rather than on competition between adenosine and ADP for platelet binding sites.

Isolation of radioactive iodothyronines for kinetic studies: a comparison of two methods

1982 ◽  
Vol 99 (1) ◽  
pp. 64-71 ◽  
Author(s):  
Jens Faber ◽  
lb Bo Lumholtz ◽  
Carsten Kirkegaard ◽  
Kaj Siersbæk-Nielsen ◽  
Thorkild Friis
Keyword(s):  
Radioactive Iodine ◽  
Single Injection ◽  
Kinetic Studies ◽  
Acid Precipitation ◽  
Relative Difference ◽  
Metabolic Clearance ◽  
Metabolic Clearance Rate ◽  
Minor Degree ◽  
A Minor

Abstract. A method based on the principle of gel separation followed by antibody extraction (GSAE) has been developed for isolation of radioactive thyroxine (T4), 3,5,3'-triiodothyronine (T3), 3,3',5'-triiodothyronine (rT3), 3,3'-diiodothyronine (3,3'-T2), 3',5'-diiodothyronine (3',5'-T2) and 3'-monoiodothyronine (3'-T1) in serum. This method was used for the estimation of the metabolic clearance rate (MCR) of the iodothyronines using the single injection, non-compartmental approach, and was compared to the conventional trichloroacetic acid precipitation/ethanol extraction (TCA-E) technique. The GSAE method excluded the co-determination of radioactive iodine and iodoproteins, whereas the co-determination of radiolabelled daughter iodothyronines was found negligible. The relative difference of duplicate estimations of MCR was approximately 10%. Using the TCA-E method for isolation of tracer, the MCR of T4, T3 and rT3 was underestimated to a minor degree (20%), whereas the MCRs of 3,3'-T2, 3',5'-T2 and 3'-T1 were 20–40% of those estimated by the GSAE method. In conclusion the GSAE method was found suitable for kinetic studies of iodothyronines, whereas the TCA-E method cannot be used for turnover studies of 3,3'-T2, 3',5'-T2 or 3'-T1.

THE EFFECTS OF TOBACCO SMOKING IN CHILDREN

PEDIATRICS ◽  
1967 ◽  
Vol 40 (3) ◽  
pp. 362-362
Author(s):  
T. E. C.
Keyword(s):  
American Medical Association ◽  
Medical Association ◽  
American Medical ◽  
Tobacco Smoking ◽  
Organic Lesion ◽  
Minor Degree ◽  
Normal Quantity ◽  
Continued Use ◽  
A Minor

The very first issue of the Journal of the American Medical Association contained the following abstract of a paper published originally in the French Revue d'Hygiene of March 20, 1883 on the evil effects of tobacco smoking in children. Dr. G. Decaisne, in a paper read before the Paris Société de Médicine Publique, gives observations upon thirty-eight children, between nine and fifteen years of age, where decided effects [due to smoking] were produced in twenty-seven. Twenty-two had disturbances of the circulation, bruit de souffle in the carotids, palpitation of the heart, difficulty in digestion, indolent intelligence and a decided taste for strong drinks. Thirteen had an intermittent pulse. Eight showed a notable diminution of blood corpuscles. Twelve had frequent attacks of nosebleed. Ten were restless in their sleep with nightmares. Two showed slight ulcerations of the buccal membrane, which disappeared promptly on their giving up smoking for a few days. In one case pulmonary phthisis seemed to have resulted from a profound alteration of the blood due to the long continued use of tobacco. In eleven children who gave up smoking entirely, with six these symptoms disappeared in less than six months; three still suffered in a minor degree at the end of a year. He concludes, as the result of his observations collected through twenty years, that the pernicious effects of smoking upon children are incontestable. That it produces intermittence of the pulse, alteration of the blood, and the principal symptoms of chloroanemia, pallor of the countenance, emaciation, bruit de souffle in the carotids, palpitation of the heart, diminution of the normal quantity of the blood corpuscles, and difficulties of digestion. That the mental faculties become sluggish, with a fondness for strong drinks. That the ordinary treatment for chloroanemia produces no effect while the habit continues, and, finally, that with those children who are without organic lesion, all these disorders disappear promptly and without leaving any traces behind, when the habit is discontinued. Could French tobacco of the 1880's have been all that potent, or was Doctor Decaisne an alarmist?

scholarly journals Alliances of Change Pushing Organizational Transformation Towards Sustainability across 13 Universities

2020 ◽  
Vol 12 (7) ◽  
pp. 2853 ◽  
Author(s):  
Lisa Bohunovsky ◽  
Verena Radinger-Peer ◽  
Marianne Penker
Keyword(s):  
Organizational Culture ◽  
Organizational Transformation ◽  
Group Discussion ◽  
Change Agency ◽  
Organizational Changes ◽  
Leading Role ◽  
Timeline Analysis ◽  
Minor Degree ◽  
Agents Of Change ◽  
A Minor

Universities are expected to play a leading role in developing and maintaining sustainability. To contribute to a systemic and dynamic understanding of organizational change that is necessary in order to play such a role, we comparatively analyzed processes of organizational changes towards sustainability across thirteen universities in Austria. This comparative analysis is based on data from guided interviews and document analysis and on validation of preliminary results via group discussion and individual comments. The results show that all universities embedded sustainability in most of their areas of activity (research, teaching, operations, organizational culture, societal engagement), but the depth of integration and the type of structural embedding varies. Especially for early changes dating back to the 1990s, academics working in the broader field of sustainability studies were those agents of change, who—without formal mandate—skillfully and proactively initiated and drove organizational transformations following an idealistic and intrinsic motivation. A timeline analysis illustrates peaks of sustainability-related changes in the years of the foundation of inter-university networks in 2011 and 2017, which acted as alliances of change. Ministry intervention in 2015 helped to bring sustainability on the agenda of those universities with less change agency. In summary, sustainability transformations across the fields of teaching, research, operations, organizational culture, and societal engagement were driven by a fruitful interplay of change agency and change alliances and to a minor degree by top-down interventions.

THE EFFECTS OF OESTROGENS AND OF MILD CHRONIC STARVATION ON THE WHITE RAT

1946 ◽  
Vol 24e (4) ◽  
pp. 105-118
Author(s):  
A. T. Cameron ◽  
Jean S. Guthrie ◽  
J. Carmichael
Keyword(s):  
Growth Rate ◽  
Oral Administration ◽  
Food Restriction ◽  
Marked Decrease ◽  
Pathological Change ◽  
The Other ◽  
Peanut Oil ◽  
Testicular Atrophy ◽  
Minor Degree ◽  
Loss Of Appetite

Daily injections of peanut oil for 17 or 18 days cause decrease in rate of growth of the rat, and testicular atrophy. Hence results in experiments in which peanut oil (and probably similar oils) are used as solvent vehicles for administration of material by injection may be misinterpreted. Oral administration of oestradiol (3 mgm. daily) to young mature rats for three weeks or more causes decrease in growth rate, relative decrease in size of kidneys, heart, spleen, muscle, and ovaries, little effect on the liver, marked decrease in size of testes, even to actual atrophy, and frequent enlargement of the adrenals in males, with occasional enlargement in females. The adrenals are discoloured to a maroon shade, whether enlarged or not, and evidence is advanced that they are undergoing a pathological change; any enlargement is not in the nature of hypertrophy. Oral administration of stilboestrol gives similar results. The general effects of oestrogens are more marked in male than in female animals. Loss of appetite and diminished food intake are among the general effects, but the mild chronic starvation so produced can only contribute in very minor degree to the other oestrogenic effects.In mild chronic starvation from food restriction the liver is invariably affected, while the adrenals are never enlarged nor discoloured.The effects of combined oestrogenic and thyroid administration seem to be neither additive nor truly antagonistic.

scholarly journals II. On the optical characters of certain alkaloids associated with quinine, and of the sulphates of their iodo-compounds. By William Bird Herapath, M. D., in a letter to Professor Stokes, Sec. R. S. Communicated by Professor Stokes

1857 ◽  
Vol 8 ◽  
pp. 340-343 ◽  
Keyword(s):  
Minor Degree ◽  
A Minor

You will probably recollect that I sent you some time since a small portion of an alkaloid, which at that time was called quinidin in Germany, but it has since been distinguished from it and named cinchonidin. You then examined it for epipolism or fluorescence, and you pronounced the opinion that it possessed this property only in a minor degree, and you imagined that this arose from the presence of a small per-centage of α -quinine. I have since obtained, through the kindness of Mr. J. E. Howard, specimens of the perfectly pure alkaloids quinidin and cinchonidin, and find that quinidin, which I can now identify as the β -quinine of Von Heijningen, possesses the phenomenon of fluorescence or epipolic dispersion as powerfully as α -quinine; whilst cinchonidin, if perfectly pure, is devoid of it altogether; and recent experiments have shown me that a small per-centage of quinidin was the cause of the epipolic dispersion found by you in the specimen of cinchonidin sent by me.

Mold Spectra of Various Foods in Relation to Plating Medium

1995 ◽  
Vol 58 (6) ◽  
pp. 661-665 ◽  
Author(s):  
M. WEIDENBÖRNER ◽  
C. WIECZOREK ◽  
B. KUNZ
Keyword(s):  
Qualitative And Quantitative ◽  
Freeze Dried ◽  
Minor Degree ◽  
A Minor

Freeze-dried strawberries and pears, raisins, sliced roasted almonds, and hazelnuts were investigated for their qualitative and quantitative mycoflora on four different media. The foodstuffs investigated showed relatively low infestation rates. Slightly higher fungus counts were observed in the case of almonds, while strawberries, hazelnuts, raisins, and pears (in decreasing order) were contaminated only to a minor degree. The mycoflora was dominated by molds of the genera Aspergillus and Penicillium and fungi of the Mucoraceae. Most fungus isolates could be enumerated from DRBC, followed by PDA and DG-18, while 7.5% MSA showed only low effectiveness. Minor differences were seen when the number of different species/genera from each medium were compared with each other. DRBC allows the isolation of the broadest spectrum of fungi. Differences between the remaining media were small.

A unified theory of surface roughness

1984 ◽  
Vol 393 (1804) ◽  
pp. 133-157 ◽  
Keyword(s):  
Surface Roughness ◽  
Rough Surface ◽  
Random Noise ◽  
Sampling Interval ◽  
The Other ◽  
Real Surface ◽  
Unified Theory ◽  
Two Dimensional ◽  
Minor Degree ◽  
A Minor

The properties of the peaks and summits of a rough surface are predicted on the assumption that the surface is two-dimensional random noise. The important result is that, in non-dimensional form, the answers depend only to a minor degree on the parameters describing the surface or on the sampling interval used: on the other hand the absolute values are strongly dependent on the sampling interval. Experimental results on a real surface agree remarkably well with the predictions.

Research on Fatigue S-N Curves of Corrosion-Damaged Reinforcement

2006 ◽  
Vol 324-325 ◽  
pp. 607-610 ◽  
Author(s):  
Hong Wei Tang ◽  
Shi Bin Li ◽  
Dong Hai Xie ◽  
Cimian Zhu
Keyword(s):  
Fatigue Tests ◽  
Concrete Bridges ◽  
Fatigue Reliability ◽  
Reinforced Concrete Bridges ◽  
Mass Losses ◽  
Minor Degree ◽  
Residual Fatigue ◽  
Severe Degree ◽  
A Minor ◽  
Define Medium

Three corrosion degrees of reinforcement are chosen in this paper, which are considered to simulate minor, medium and severe degrees of corrosion in this field. A reinforcement mass loss about 5% is used to define a minor degree of corrosion, whereas mass losses about 10% and 20% are used to define medium and severe degree of corrosion, respectively. Fifteen specimens of the three corrosion degrees and seven uncorroded specimens are tested under fatigue. According to the results of the fatigue tests, using stress range as fatigue parameter and 50% as guaranteed probability, the fatigue S-N curves of the four different corrosion degrees of deformed reinforcement adaptable for fatigue reliability evaluation are put forward. These curves provide necessary principle for predicting the residual fatigue lives of aged existing reinforced concrete bridges.

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