scholarly journals Improving cross-species extrapolation of chemical sensitivity

2020 ◽  
Author(s):  
Sanne van den Berg
2021 ◽  
Vol 753 ◽  
pp. 141800 ◽  
Author(s):  
Sanne J.P. van den Berg ◽  
Lorraine Maltby ◽  
Tom Sinclair ◽  
Ruoyu Liang ◽  
Paul J. van den Brink

2002 ◽  
Vol 41 (06) ◽  
pp. 233-239 ◽  
Author(s):  
C. Hausteiner ◽  
A. Drzezga ◽  
P. Bartenstein ◽  
M. Schwaiger ◽  
H. Förstl ◽  
...  

SummaryAim: Multiple chemical sensitivity (MCS) is a controversially discussed symptom complex. Patients afflicted by MCS react to very low and generally nontoxic concentrations of environmental chemicals. It has been suggested that MCS leads to neurotoxic damage or neuroimmunological alteration in the brain detectable by positron emission tomography (PET) and single photon emission computer tomography (SPECT). These methods are often applied to MCS patients for diagnosis, although they never proved appropriate. Method: We scanned 12 MCS patients with PET, hypothesizing that it would reveal abnormal findings. Results: Mild glucose hypometabolism was present in one patient. In comparison with normal controls, the patient group showed no significant functional brain changes. Conclusion: This first systematic PET study in MCS patients revealed no hint of neurotoxic or neuroimmuno-logical brain changes of functional significance.


2005 ◽  
Vol 59 (11) ◽  
pp. 1631-1635
Author(s):  
Yukio Yanagisawa
Keyword(s):  

Author(s):  
Hong-Jae Chae ◽  
Byoung-Gwon Kim ◽  
Hwan-Cheol Kim ◽  
Mi-Young Lee ◽  
Jong-Han Leem

Sensors ◽  
2021 ◽  
Vol 21 (5) ◽  
pp. 1799
Author(s):  
Tianyu Yang ◽  
Liang Zhang ◽  
Yunjie Shi ◽  
Shidi Liu ◽  
Yuming Dong

A photonic crystal fiber (PCF) with high relative sensitivity was designed and investigated for the detection of chemical analytes in the terahertz (THz) regime. To ease the complexity, an extremely simple cladding employing four struts is adopted, which forms a rectangular shaped core area for filling with analytes. Results of enormous simulations indicate that a minimum 87.8% relative chemical sensitivity with low confinement and effective material absorption losses can be obtained for any kind of analyte, e.g., HCN (1.26), water (1.33), ethanol (1.35), KCN (1.41), or cocaine (1.50), whose refractive index falls in the range of 1.2 to 1.5. Besides, the PCF can also achieve high birefringence (∼0.01), low and flat dispersion, a large effective modal area, and a large numerical aperture within the investigated frequency range from 0.5 to 1.5 THz. We believe that the proposed PCF can be applied to chemical sensing of liquid and THz systems requiring wide-band polarization-maintaining transmission and low attenuation.


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