scholarly journals Anaerobic manganese- or iron-mediated pharmaceutical degradation in water

2018 ◽  
Author(s):  
Wenbo Liu
Keyword(s):  
Pharmaceutical Degradation

scholarly journals Degradation of the pharmaceuticals lamivudine and zidovudine using advanced oxidation processes

2020 ◽  
Vol 42 ◽  
pp. e9
Author(s):  
Alex Leandro Andrade de Lucena ◽  
Daniella Carla Napoleão ◽  
Hélder Vinícius Carneiro da Silva ◽  
Rayany Magali da Rocha Santana ◽  
Beatriz Galdino Ribeiro ◽  
...  
Keyword(s):  
Lactuca Sativa ◽  
Advanced Oxidation Processes ◽  
Advanced Oxidation ◽  
Kinetic Studies ◽  
Degradation Process ◽  
Oxidation Processes ◽  
First Order ◽  
Input Variables ◽  
Pharmaceutical Degradation ◽  
Uv C

The existence of pharmaceuticals in nature is a growing environmental problem, turning necessary the use of efficient treatments for the degradation of these substances, as the advanced oxidation processes (AOPs). In this work the AOPs UV/H2O2 and photo-Fenton were applied to degrade the pharmaceuticals lamivudine and zidovudine in an aqueous solution using a bench reactor, composed of three UV-C lamps. It was verified that the UV/H2O2 process presented a degradation of 97.33 ± 0.14% for lamivudine and 93.90 ± 0.33% for zidovudine, after 180 min of treatment and for an initial concentratin of each pharmaceutical of  5 mg.L-1 and [H2O2] of 600 mg.L-1.  A methodology by artificial neural networks (ANNs) was used to model the photocatalytic process, with the MLP 7-23-2 ANN representing it well, and determining the relative importance (%) of each of the input variables for the pharmaceutical’s degradation process. Kinetic studies for the pharmaceutical degradation and the conversion of organic matter showed good adjustments to the pseudo first-order models with R2 raging from 0.9705 to 0.9980. Toxicity assays for the before treatment solution indicated that the seeds Lactuca sativa and Portulaca grandiflora showed growth inhibition whereas the post-treatment solution inhibited only the growth of Lactuca sativa.

Predicting pharmaceutical degradation by UV (LP)/H2O2 processes: A kinetic model

2014 ◽  
Vol 255 ◽  
pp. 334-343 ◽  
Author(s):  
B.A. Wols ◽  
D.J.H. Harmsen ◽  
E.F. Beerendonk ◽  
C.H.M. Hofman-Caris
Keyword(s):  
Kinetic Model ◽  
Pharmaceutical Degradation

Degradation of acetaminophen (ACT) by ozone/persulfate oxidation process: experimental and degradation pathways

2020 ◽  
Vol 49 (5) ◽  
pp. 363-368
Author(s):  
Maryam Khashij ◽  
Mohammad Mehralian ◽  
Zahra Goodarzvand Chegini
Keyword(s):  
Removal Efficiency ◽  
Emerging Contaminants ◽  
Oxidation Process ◽  
Batch Reactor ◽  
Degradation Efficiency ◽  
Content Type ◽  
Persulfate Oxidation ◽  
Personal Care Product ◽  
Pathway Inference ◽  
Pharmaceutical Degradation

Purpose The purpose of this study to investigate acetaminophen (ACT) degradation efficiencies by using ozone/persulfate oxidation process in a batch reactor. In addition, the effects of various parameters on the ACT removal efficiency toward pathway inference of ACT degradation were investigated. Design/methodology/approach The experiments were in the 2 L glass vessels. Ozone gas with flow rate at 70 L.h−1 was produced by ozone generator. After the adjustment of the pH, various dosages of persulfate (1, 3, 5, 7 and 9 mmol.L−1) were then added to the 500 mL ACT-containing solution with 150 mg.L−1 of concentration. Afterward, ozone gas was diffused in glass vessels. The solution after reaction flowed into the storage tank for the detection. The investigated parameters included pH and the amount of ozone and persulfate addition. For comparison of the ACT degradation efficiency, ozone/persulfate, ozone and persulfate oxidation in reactor was carried out. The ACT concentration using a HPLC system equipped with 2998 PDA detector was determined at an absorbance of 242 nm. Findings ACT degradation percentage by using ozone or persulfate in the process were at 63.7% and 22.3%, respectively, whereas O3/persulfate oxidation process achieved degradation percentage at 91.4% in 30 min. Degradation efficiency of ACT was affected by different parameter like pH and addition of ozone or persulfate, and highest degradation obtained when pH and concentrations of persulfate and ozone was 10 and 3 mmol.L−1 and 60 mg.L−1, respectively. O3, OH• and SO4− were evidenced to be the radicals for degradation of ACT through direct and indirect oxidation. Gas chromatography–mass spectrometer analysis showed intermediates including N-(3,4-dihydroxyphenyl) formamide, hydroquinone, benzoic acid, 4-methylbenzene-1,2-diol, 4-aminophenol. Practical implications This study provided a simple and effective way for degradation of activated ACT as emerging contaminants from aqueous solution. This way was conducted to protect environment from one of the most important and abundant pharmaceutical and personal care product in aquatic environments. Originality/value There are two main innovations. One is that the novel process is performed successfully for pharmaceutical degradation. The other is that the optimized conditions are obtained. In addition, the effects of various parameters on the ACT removal efficiency toward pathway inference of ACT degradation were investigated.

Effect of oxidation on amine-based pharmaceutical degradation and N-Nitrosodimethylamine formation

2015 ◽  
Vol 87 ◽  
pp. 403-411 ◽  
Author(s):  
Xiaofeng Wang ◽  
Hongwei Yang ◽  
Beihai Zhou ◽  
Xiaomao Wang ◽  
Yuefeng Xie
Keyword(s):  
Pharmaceutical Degradation

In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study

2014 ◽  
Vol 11 (11) ◽  
pp. 4179-4188 ◽  
Author(s):  
Mark H. Kleinman ◽  
Steven W. Baertschi ◽  
Karen M. Alsante ◽  
Darren L. Reid ◽  
Mark D. Mowery ◽  
...  
Keyword(s):  
In Silico ◽  
Degradation Pathways ◽  
In Silico Prediction ◽  
Pharmaceutical Degradation

scholarly journals Enhanced visible light photocatalysis by TiO2–BN enabled electrospinning of nanofibers for pharmaceutical degradation and wastewater treatment

2019 ◽  
Vol 18 (12) ◽  
pp. 2921-2930 ◽  
Author(s):  
Lu Lin ◽  
Wenbin Jiang ◽  
Maryline Nasr ◽  
Mikhael Bechelany ◽  
Philippe Miele ◽  
...  
Keyword(s):  
Wastewater Treatment ◽  
Surface Chemistry ◽  
Visible Light ◽  
Organic Contaminants ◽  
Visible Light Photocatalysis ◽  
Pharmaceutical Degradation

Electrospun TiO2–BN nanofibers were characterized to understand surface chemistry and elucidate mechanisms for degradation of organic contaminants in wastewater.

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