scholarly journals Evaluation of Cases Presenting to a University Hospital Psychiatry Clinic for the Determination of Disability

2021 ◽  
Vol 26 (3) ◽  
pp. 158-163
Author(s):  
Zekiye Çelikbaş ◽  
Sedat Batmaz ◽  
Esma Akpınar Aslan
Keyword(s):  
University Hospital ◽  
Psychiatry Clinic ◽  
Hospital Psychiatry

A comparison of spleen size measured by ultrasound in a random population sample and a matched sample of patients at a university hospital, and the determination of normal values and influencing factors

2021 ◽  
Author(s):  
Theresa Schranz ◽  
Jochen Klaus ◽  
Wolfgang Kratzer ◽  
Julian Schmidberger ◽  
Melanie Güthle
Keyword(s):  
Normal Values ◽  
Population Sample ◽  
Body Height ◽  
University Hospital ◽  
Spleen Size ◽  
The Mean ◽  
Random Population Sample ◽  
Hospital Sample

Abstract Objectives This study aimed to compare spleen sizes in a hospital and a population sample using ultrasound and define normal values and factors influencing spleen size. Methods Both samples’ spleen sizes (n = 1520) were measured using ultrasound under the same conditions. Blood counts and other laboratory parameters were determined under the same conditions in both samples. Results In the hospital sample (n = 760), the mean spleen size was 114.7 mm, and in the population sample (n = 760), it was 99.1 mm. In both, spleen size in men was significantly higher than in women (p < 0.0001) and influenced by body height, weight, and BMI (body mass index) (p < 0.0001). In the hospital sample, there was a correlation with higher values for ALT (p = 0.0160), AST (p = 0.0394), AP (p = 0.0482), and ferritin (p = 0.0008) and lower values for HDL (p = 0.0091) and thrombocytes (p < 0.0001). In the multivariate analysis, higher values for AP (p = 0.0059) and lower values for hemoglobin (p = 0.0014) and thrombocytes (p = 0.0001) were found. Stratified for sex (men, women), spleen size increased with higher values for ALT (p = 0.0116, p = 0.0113), AST (p = 0.0014, p = 0.0113), and AP (p = 0.0001, p = 0.0012), and with lower values of hemoglobin (p = 0.0057, p = 0.0016), thrombocytes (p < 0.0001, p = 0.0003), and albumin (p = 0.0029, p = 0.0432). In women, there was a discordant correlation with red blood cells (p = 0.0005) and a concordant correlation with GGT (p = 0.0241), and in men discordant correlations with cholesterol (p = 0.0010) and HDL (p = 0.0404). Conclusions The already proven impact of anthropometric data on spleen size was confirmed. The role of laboratory values should be further analyzed.

scholarly journals Antimicrobial resistance in clinical isolates of Ureaplasma spp. from samples in Germany

2021 ◽  
Author(s):  
Roger Dumke
Keyword(s):  
Antimicrobial Resistance ◽  
Ureaplasma Urealyticum ◽  
Urogenital Tract ◽  
Molecular Methods ◽  
Clinical Isolates ◽  
University Hospital ◽  
Minimal Inhibitory Concentrations ◽  
Ureaplasma Spp

Ureaplasma urealyticum and U. parvum are mollicutes species that colonize the urogenital tract of many asymptomatic persons but are also thought to be associated with symptomatic infections. Using 170 strains isolated between 2016 and 2019 in a German university hospital, resistance was tested by a combination of commercial tests, molecular methods and determination of minimal inhibitory concentrations. Rates of resistance to macrolides, tetracyclines and fluoroquinolones were 0%, 4.1% and 7.1%, respectively.

scholarly journals Determination of Compassion Levels of Nurses Working at a University Hospital

2019 ◽  
Vol 59 (1) ◽  
pp. 29-39 ◽  
Author(s):  
B. Arkan ◽  
D. Yılmaz ◽  
F. Düzgün
Keyword(s):  
University Hospital

scholarly journals Late decisions about treatment limitation in patients with cancer: empirical analysis of end-of-life practices in a haematology and oncology unit at a German university hospital

ESMO Open ◽  
2020 ◽  
Vol 5 (5) ◽  
pp. e000950
Author(s):  
Katja Mehlis ◽  
Elena Bierwirth ◽  
Katsiaryna Laryionava ◽  
Friederike Mumm ◽  
Pia Heussner ◽  
...  
Keyword(s):  
Palliative Care ◽  
Advance Care Planning ◽  
Solid Tumours ◽  
University Hospital ◽  
Care Planning ◽  
Do Not Resuscitate ◽  
Treatment Limitation ◽  
Ethics Policy ◽  
Advance Care

BackgroundDecisions to limit treatment (DLTs) are important to protect patients from overtreatment but constitute one of the most ethically challenging situations in oncology practice. In the Ethics Policy for Advance Care Planning and Limiting Treatment study (EPAL), we examined how often DLT preceded a patient’s death and how early they were determined before (T1) and after (T2) the implementation of an intrainstitutional ethics policy on DLT.MethodsThis prospective quantitative study recruited 1.134 patients with haematological/oncological neoplasia in a period of 2×6 months at the University Hospital of Munich, Germany. Information on admissions, discharges, diagnosis, age, DLT, date and place of death, and time span between the initial determination of a DLT and the death of a patient was recorded using a standardised form.ResultsOverall, for 21% (n=236) of the 1.134 patients, a DLT was made. After implementation of the policy, the proportion decreased (26% T1/16% T2). However, the decisions were more comprehensive, including more often the combination of ‘Do not resuscitate’ and ‘no intense care unit’ (44% T1/64% T2). The median time between the determination of a DLT and the patient’s death was similarly short with 6 days at a regular ward (each T1/T2) and 10.5/9 (T1/T2) days at a palliative care unit. For patients with solid tumours, the DLTs were made earlier at both regular and palliative care units than for the deceased with haematological neoplasia.ConclusionOur results show that an ethics policy on DLT could sensitise for treatment limitations in terms of frequency and extension but had no significant impact on timing of DLT. Since patients with haematological malignancies tend to undergo intensive therapy more often during their last days than patients with solid tumours, special attention needs to be paid to this group. To support timely discussions, we recommend the concept of advance care planning.

scholarly journals EFFECTIVENESS OF PROSTHODONTIC TREATMENT OF PATIENTS WITH INCREASED DENTAL ATTRITION ON THE BASIS OF FUNCTIONAL DIAGNOSTIC

2018 ◽  
Vol 22 (6) ◽  
pp. 297-300
Author(s):  
Alexander S. Romanov ◽  
V. G Morozov ◽  
P. N Geletin
Keyword(s):  
Dental Treatment ◽  
University Hospital ◽  
Control Group ◽  
Dental Attrition ◽  
Before And After ◽  
Medical University ◽  
Methods Of Treatment ◽  
Functional Diagnostic ◽  
Group 1

Aim of the present study was to evaluate the effectiveness of prosthodontic methods of treatment based of functional diagnostic of patients with increased dental attrition Methods. We have examined 35 patients at the Smolensk State Medical University Hospital: 20 patients with increased dental attrition and 15 patients who didn’t have any sign of functional disorders of dentoalveolar and musculoskeletal system. The main group was divided into two subgroups. In the group 1 (11 patients) required a prosthodontic therapy included individual wax-up of future prosthetic construction based on data of functional diagnostic. An electromyographic study was conducted before and one month after treatment for determination of the effectiveness of treatment methods. Results. Analyzing and comparing the data of the electromyographic study 1 month before and after treatment of patients of the 1 group have shown 93,1 % effectiveness of the treatment and the control group. The results of the study show that such occlusion is optimal for the muscles and temporomandibular joint. Conclusion. Dental treatment of increased attrition of teeth based on functional diagnostic contributes to the normalization of muscles activity. Moreover it allows to protect teeth from attrition and providing effective rehabilitation of patients.

scholarly journals Road Map fluoroscopy successfully guides endoscopic interventions in the esophagus

2017 ◽  
Vol 05 (07) ◽  
pp. E608-E612
Author(s):  
Jochen Weigt ◽  
Wilfried Obst ◽  
Arne Kandulski ◽  
Maciej Pech ◽  
Ali Canbay ◽  
...  
Keyword(s):  
University Hospital ◽  
Radiographic Imaging ◽  
Image Subtraction ◽  
Diagnostic Endoscopy ◽  
Endoscopic Control ◽  
Road Map ◽  
Esophageal Strictures ◽  
Stent Length ◽  
Radiological Technique

Abstract Background and study aims Road Map (RM) fluoroscopy is a radiological technique that enables visualization of anatomic structures using image subtraction at peak opacification. RM fluoroscopy has never previously been evaluated for use in endoscopy. The aim of this study was to evaluate the usefulness of RM in guiding endoscopic intervention in the esophagus. Patients and methods This was a monocentric observational trial of consecutive patients with esophageal strictures in a university hospital. Twenty-seven investigations using RM were performed in 24 patients undergoing esophageal endoscopy. Indications for the procedure were balloon dilatation (n = 7 including 2 pneumatic balloon dilatations for treatment of achalasia), bougie dilatation (n = 7) and diagnostic endoscopy (n = 1). In addition, 12 stents, 7 partially covered and 5 fully covered, were placed using RM as a guide for determination of stent length and diameter. Stents were deployed under RM guidance. Results In all procedures, RM successfully guided the intervention. Endoscopic control endoscopy confirmed adequate stent placement in all cases.The feeling of resistance during bougie dilation matched the RM-predicted location of the stenosis. With the help of RM imaging, dilatation balloons were easily centered inside the stenosis and thus slipping of the balloon was avoided. There were no adverse events. Conclusion RM allows permanent and accurate radiographic imaging of stenoses and esophageal anatomic changes. It is an easy and safe method of guiding endoscopic interventions that require radiological imaging.

scholarly journals Reduced Androgen Receptor Expression in Genital Skin Fibroblasts From Patients With 45,X/46,XY Mosaicism

2019 ◽  
Vol 104 (10) ◽  
pp. 4630-4638 ◽  
Author(s):  
Nadine C Hornig ◽  
Jeta Demiri ◽  
Pascal Rodens ◽  
Eva Maria Murga Penas ◽  
Almuth Caliebe ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Mrna Expression ◽  
Molecular Mechanisms ◽  
Phenotypic Diversity ◽  
Phenotypic Variability ◽  
Skin Fibroblasts ◽  
Receptor Expression ◽  
University Hospital ◽  
Positive Trend

Abstract Context Molecular mechanisms causing the broad phenotypic diversity of external masculinization in individuals with 45,X/46,XY mosaicism are poorly understood. Objective Analysis of androgen receptor (AR) expression and function as a putative influencing factor for the genital phenotype in patients with 45,X/46,XY mosaicism. Design Measurement of AR mRNA expression levels, AR activity [DHT-mediated APOD (apolipoprotein D) induction] and cellular 45,X/46,XY ratios in genital skin fibroblasts from individuals with 45,X/46,XY mosaicism and male reference individuals, and determination of the external virilization scale from individuals with 45,X/46,XY mosaicism. Setting University hospital endocrine research laboratory. Patients or Other Participants: 30 genital skin fibroblast cultures (GFs) from male reference individuals and 15 GFs from individuals with 45,X/46,XY mosaicism. Intervention None Main Outcome Measures Determination of AR mRNA expression and AR activity in male reference GFs and 45,X/46,XY GFs and correlation of the obtained data with the cellular 45,X/46,XY ratios and the patients’ external virilization scale. Results In 6 of 15 45,X/46,XY GFs, AR mRNA expression and AR activity were significantly lower compared with those in the 46,XY reference GFs. In this subgroup of reduced AR mRNA expression, a positive trend was seen between AR mRNA expression and the percentage of XY-positive cells. Furthermore, we found a positive correlation between AR activity and the external virilization scale in the 15 45,X/46,XY GF samples (P = 0.03). Conclusion Our results suggest that AR expression and AR activity might influence the phenotypic variability seen in patients with 45,X/46,XY mosaicism.

Sign in / Sign up

Export Citation Format

Share Document