scholarly journals Decreased levels of the serum inflammatory biomarkers, sGP130, IL-6, sCRP and BAFF, are associated with increased likelihood of AIDS related Kaposi’s sarcoma in men who have sex with men.

2018 ◽  
Vol 4 (1) ◽  
pp. 45-59 ◽  
Author(s):  
Rachel Bolanos ◽  
◽  
Otoniel Martinez-Maza ◽  
Zuo-Feng Zhang ◽  
Shehnaz Hussain ◽  
...  
2013 ◽  
Vol 85 (6) ◽  
pp. 1046-1052 ◽  
Author(s):  
Harutaka Katano ◽  
Yoshiyuki Yokomaku ◽  
Hitomi Fukumoto ◽  
Takayuki Kanno ◽  
Tomoyuki Nakayama ◽  
...  

2008 ◽  
Vol 35 (12) ◽  
pp. 1011-1014
Author(s):  
Abigail M. Phillips ◽  
Alison Graves Jones ◽  
Dennis H. Osmond ◽  
Lance M. Pollack ◽  
Joseph A. Catania ◽  
...  

2018 ◽  
Vol 32 (8) ◽  
pp. 1377-1384 ◽  
Author(s):  
D. Denis ◽  
V. Seta ◽  
E. Regnier-Rosencher ◽  
N. Kramkimel ◽  
J. Chanal ◽  
...  

2006 ◽  
Vol 120 (5) ◽  
pp. 1129-1135 ◽  
Author(s):  
Elisa Martró ◽  
Anna Esteve ◽  
Thomas F. Schulz ◽  
Julie Sheldon ◽  
Gemma Gambús ◽  
...  

2012 ◽  
Vol 141 (9) ◽  
pp. 1823-1830 ◽  
Author(s):  
T. ZHANG ◽  
H. LIN ◽  
V. MINHAS ◽  
W. ZHU ◽  
C. WOOD ◽  
...  

SUMMARYThis study aimed to determine the seroprevalence of Kaposi's sarcoma-associated herpesvirus (KSHV) and related factors in men who have sex with men (MSM) in China. A total of 208 subjects were recruited from eastern China from 2008 to 2009. Plasma samples were collected and screened for KSHV, HIV and syphilis. Overall, KSHV seroprevalence was 32·7% in the subjects. About 92·7% of subjects reported having ever had anal sex with a man, of whom 67·8% had receptive anal sex and 77·9% had insertive anal sex. About 93·1% of the study participants reported having had oral sex with a man, of whom 76·0% had receptive oral sex and 56·7% had insertive oral sex. KSHV seropositivity was independently associated with receptive anal sex [odds ratio (OR) 2·68, 95% confidence interval (CI) 1·15–6·23], syphilis (OR 3·25, 95% CI 1·56–6·76) and HSV-2 infection (OR 2·40, 95% CI 1·09–5·26). KSHV infection is highly prevalent and is probably sexually transmitted among MSM in eastern China.


Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5692
Author(s):  
Sophie Grabar ◽  
Dominique Costagliola

Kaposi’s sarcoma is an angioproliferative tumor caused by human herpesvirus 8 in the context of immunodeficiency, such as that induced by HIV infection or immunosuppressive therapy. Its incidence has dramatically fallen in patients living with HIV (PLHIV) since the introduction of potent antiretroviral combinations 25 years ago due to the restoration of immunity and better control of HIV replication. However, KS is still one of the most frequently occurring cancers in PLHIV, in particular in men who have sex with men and in sub-Saharan Africa, where it is still endemic. Even in the context of restored immunity, the risk of KS is still more than 30 times higher in PLHIV than in the general population. Recent evidence indicates that early initiation of antiretroviral treatment, which is recommended by current guidelines, may reduce the risk of KS but it needs to be accompanied by early access to care. This review mainly focuses on the recent epidemiological features of KS in the context of HIV infection.


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