Expanding Indications of Imaging with Optovue Optical Coherence Tomography in Children

2012 ◽  
Vol 06 (01) ◽  
pp. 7
Author(s):  
Matteo Sacchi ◽  
Massimiliano Serafino ◽  
Paolo Nucci ◽  
◽  
◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Congenital Cataract ◽  
Cataract Extraction ◽  
Posterior Capsule ◽  
Optical Coherence ◽  
Corneal Incision ◽  
Paediatric Ophthalmology ◽  
Incision Healing ◽  
Sd Oct

Although interest in optical coherence tomography (OCT) has increased markedly during the past decade in many fields of ophthalmology, there are only a few reports of the use of spectral domain (SD)-OCT in paediatric ophthalmology. In this article, the authors describe the use of SD-OCT in children as a new indication for OCT. Paediatric patients with aniridia were examined for the presence of keratopaty, cataract, glaucoma and foveal hypoplasia. Children with cataracts were followed for six months after surgery. The type of cataract, intraocular lens position, posterior capsule opacity and corneal incision healing were visualised by SD-OCT. In total, 24 eyes with aniridia and seven eyes with congenital cataract were enrolled. OCT was able successfully to detect ocular conditions associated with aniridia. After cataract extraction, OCT was also used to follow corneal incision healing and the development of posterior capsule opacity. In children with aniridia and congenital cataract, OCT can provide clinically relevant information. With the introduction of new generation, high-speed OCT, paediatric ophthalmology is likely to become a new and interesting target for OCT.

scholarly journals Study on cerebral vascular image of spectral domain optical coherence tomography with compressive sensing

2013 ◽  
Vol 11 (3) ◽  
pp. 2355-2359
Author(s):  
Ping Xu ◽  
Zhaoyang Jin ◽  
Yong Yang
Keyword(s):  
Optical Coherence Tomography ◽  
Compressed Sensing ◽  
High Speed ◽  
Signal To Noise Ratio ◽  
Spectral Domain ◽  
Optical Coherence ◽  
L1 Norm ◽  
High Speed Imaging ◽  
Sd Oct ◽  
Cerebral Vascular

We propose a novel compressed sensing method to retrieve cerebral vascular image for spectral-domain optical coherence tomography (SD OCT). The compressed sensing method based on l1 norm minimization is applied to reconstruct each A-scan data. The proposed method uses about 25% of the total data as required in traditional SD OCT to reconstruct the cerebral angiograpy. Therefore this method is favorable for high speed imaging for cerebral angiograpy. It is shown that the proposed method can achieve better performance of axial resolution and higher signal-to-noise ratio (SNR) as compared with the conventional methods.

scholarly journals Laser Lens Size Measurement Using Swept-Source Optical Coherence Tomography

2020 ◽  
Vol 10 (14) ◽  
pp. 4936
Author(s):  
Pingping Jia ◽  
Hong Zhao ◽  
Yuwei Qin
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Wave Number ◽  
Radius Of Curvature ◽  
Optical Coherence ◽  
Swept Source ◽  
Laser Focusing ◽  
Fitting Algorithm ◽  
Laser Confocal Microscope ◽  
Focusing Lens

A high-speed, high-resolution swept-source optical coherence tomography (SS-OCT) is presented for focusing lens imaging and a k-domain uniform algorithm is adopted to find the wave number phase equalization. The radius of curvature of the laser focusing lens was obtained using a curve-fitting algorithm. The experimental results demonstrate that the measuring accuracy of the proposed SS-OCT system is higher than the laser confocal microscope. The SS-OCT system has great potential for surface topography measurement and defect inspection of the focusing lens.

scholarly journals Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography

2007 ◽  
Vol 15 (26) ◽  
pp. 18130 ◽  
Author(s):  
Ki Hean Kim ◽  
B. Hyle Park ◽  
Gopi N. Maguluri ◽  
Tom W. Lee ◽  
Fran J. Rogomentich ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Optical Coherence

scholarly journals Spectral-domain optical coherence tomography for evaluating palisades of Vogt in ocular surface disorders with limbal involvement

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ying-Yi Chen ◽  
Yi-Chen Sun ◽  
Chia-Ying Tsai ◽  
Hsiao-Sang Chu ◽  
Jo-Hsuan Wu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ocular Surface ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Slit Lamp ◽  
Ocular Rosacea ◽  
Unilateral Disease ◽  
Healthy Eyes ◽  
Slit Lamp Biomicroscopy ◽  
Sd Oct

AbstractSpectral-domain optical coherence tomography (SD-OCT) has been used to observe the morphology of the palisades of Vogt (POV) with satisfactory resolutions. In this study, we used SD-OCT to examine the microstructure of the POV in ocular surface disorders with limbal involvement. We detect subclinical limbal pathologies based on five parameters, including (1) decreased epithelial thickness, (2) loss of the sharp stromal tip, (3) loss of the smooth epithelial-stromal interface, (4) dilated stromal vessels, and (5) decreased POV density. Eighteen eyes of 10 patients with advancing wavelike epitheliopathy (AWE) and 15 eyes of 9 patients with phlyctenular keratitis/ocular rosacea were recruited. SD-OCT could detect abnormal changes in the POV in 100% of the lesion sites. In presumed-healthy areas of the diseased eyes diagnosed by slit-lamp biomicroscopy, SD-OCT detected abnormal changes in the POV in 100% of the eyes in both groups. In patients with unilateral disease, abnormal changes in the POV were detected by SD-OCT in 50% and 100% of presumed-healthy eyes diagnosed by slit-lamp biomicroscopy in the AWE group and phlyctenular keratitis/ocular rosacea group, respectively. SD-OCT is powerful in detecting POV changes in ocular surface disorders and can provide useful information that cannot be provided by slit-lamp biomicroscopy.

scholarly journals Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

2018 ◽  
Vol 2018 ◽  
pp. 1-22 ◽  
Author(s):  
Farid Atry ◽  
Israel Jacob De La Rosa ◽  
Kevin R. Rarick ◽  
Ramin Pashaie
Keyword(s):  
Optical Coherence Tomography ◽  
Imaging System ◽  
Optical Design ◽  
Spectral Domain ◽  
Design Parameters ◽  
Optical Coherence ◽  
Custom Made ◽  
Essential Knowledge ◽  
Sd Oct

In the past decades, spectral-domain optical coherence tomography (SD-OCT) has transformed into a widely popular imaging technology which is used in many research and clinical applications. Despite such fast growth in the field, the technology has not been readily accessible to many research laboratories either due to the cost or inflexibility of the commercially available systems or due to the lack of essential knowledge in the field of optics to develop custom-made scanners that suit specific applications. This paper aims to provide a detailed discussion on the design and development process of a typical SD-OCT scanner. The effects of multiple design parameters, for the main optical and optomechanical components, on the overall performance of the imaging system are analyzed and discussions are provided to serve as a guideline for the development of a custom SD-OCT system. While this article can be generalized for different applications, we will demonstrate the design of a SD-OCT system and representative results for in vivo brain imaging. We explain procedures to measure the axial and transversal resolutions and field of view of the system and to understand the discrepancies between the experimental and theoretical values. The specific aim of this piece is to facilitate the process of constructing custom-made SD-OCT scanners for research groups with minimum understanding of concepts in optical design and medical imaging.

scholarly journals External limiting membrane: retinal structural barrier in diabetic macular edema

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Barrier Effect ◽  
External Limiting Membrane ◽  
Ellipsoid Zone ◽  
Structural Barrier ◽  
Sd Oct

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.

Reliability of Corneal, Epithelial, and Stromal Thickness Mapping for a 9-mm Zone Using Spectral-Domain Optical Coherence Tomography

2021 ◽  
Author(s):  
Daniel Krause ◽  
Niklas Mohr ◽  
Mehdi Shajari ◽  
Wolfgang J. Mayer ◽  
Siegfried Priglinger ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraclass Correlation ◽  
Age Groups ◽  
Corneal Stroma ◽  
Correlation Coefficients ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Noninvasive Technique ◽  
Intraclass Correlation Coefficients ◽  
Sd Oct

Abstract Purpose To evaluate the reliability of spectral-domain optical coherence tomography (SD-OCT; RTVue XR; Optovue, Inc., Fremont, CA, USA) for thickness mapping of the entire cornea (CT), corneal epithelium (ET). and corneal stroma (ST) over a 9-mm zone in healthy eyes. We sought to develop reference values for different age groups and elucidate potential sex- and age-dependent characteristics of corneal sublayer pachymetry maps. Methods Three consecutive SD-OCT scans were obtained in 166 healthy right eyes (mean age = 50 ± 20 years). The thickness maps contain 25 sectors over a 9-mm diameter zone. To test measurement reliability, intraclass correlation coefficients (ICC), coefficients of variation (CoV), and within-subject standard deviations (WSSD) were calculated. Results CT, ET, and ST ICCs ranged from 0.961 to 0.998, 0.896 to 0.945, and 0.955 to 0.998, respectively. CoV values for CT, ET, and ST ranged between 0.3 and 1.5%, 1.6 and 4.2%, and 0.4 and 1.7%, respectively. WSSD ranged from 6 to 41, 4 to 8, and 7 to 46 µm, respectively. A negative correlation was found between age and ET (p < 0.05) but not between age and ST or CT. No gender-related differences in CT, ET, or ST were detected. CoV of CT, ET, and ST measurements showed a positive correlation with age in 28, 64, and 28% of the sectors, respectively. Conclusion SD-OCT is a rapid and noninvasive technique that provides excellent reliability for corneal sublayer thickness measurements over a 9-mm zone. The reliability of the ET measurement seems to be negatively affected by age. Peripheral CT and global ET thin with age.

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