The relationships among psychological distress, stress, disease symptom activity, and coping in adolescents diagnosed with Crohn's disease

2021 ◽  
Author(s):  
Melissa Shepanski Xanthopoulos
2016 ◽  
Vol 150 (4) ◽  
pp. S433
Author(s):  
Chunhui Bao ◽  
Peng Liu ◽  
Huirong Liu ◽  
Luyi Wu ◽  
Xiaoming Jin ◽  
...  

2018 ◽  
Vol 154 (1) ◽  
pp. S49
Author(s):  
Shmuel Odes ◽  
Vered Slonim-Nevo ◽  
Ruslan Sergienko ◽  
Michael Friger ◽  
Doron Schwartz ◽  
...  

2018 ◽  
Vol 24 (suppl_1) ◽  
pp. S34-S34
Author(s):  
Shmuel Odes ◽  
Vered Slonim-Nevo ◽  
Ruslan Sergienko ◽  
Michael Friger ◽  
Doron Schwartz ◽  
...  

2021 ◽  
Vol 1 (1) ◽  
pp. 106-110
Author(s):  
E. N. Fedulova ◽  
O. V. Shumilova ◽  
N. Yu. Shirokova

Objective: to identify markers of tissue hypoxia in Crohn’s disease in children: markers and methods for overcoming it.Materials and methods: 27 children with Crohn’s disease (CD) aged from 1 year to 18 years were examined. Histological, histomorphometric and immunohistochemical analysis of biopsy samples of the colon mucosa.Results: morphological markers of tissue hypoxia in CD were identified: the presence of predominantly immature fibroblasts, infiltration of the muscle plate by neutrophilic granulocytes, necrotizing vasculitis, the phenomenon of the grouping of inactive macrophages with each other with the formation of multinucleated cells, which are the precursors of multinucleated granules according to the Pigorov-Lanhans typeConclusion: in identifying markers of tissue hypoxia, leading to a worsening prognosis of the course of CD and the development of complications, it is necessary to determine the tactics of accelerated “step-up” therapy using anticytokine drugs and use the method of hyperbaric oxygenation.


2019 ◽  
Vol 56 (2) ◽  
pp. 131-140 ◽  
Author(s):  
Arlete Silva ACCIARI ◽  
Raquel Franco LEAL ◽  
Cláudio Saddy Rodrigues COY ◽  
Cristiana Corrrêa DIAS ◽  
Maria de Lourdes Setsuko AYRIZONO

ABSTRACT BACKGROUND: Crohn’s disease is chronic, requires prolonged treatment, affects the physical and psychosocial health of patients and may alter their routine, quality of life and well-being. Recent studies recommend monitoring the health of these patients considering physical, psychological and psychosocial aspects, because they are directly related to the disease activity. These studies highlight the relevance of patients’ emotional and behavioral conditions and suggest that the identification of the factors that influence the psychological well-being, resilience and Coping in these patients can favor the proper treatment. OBJECTIVE: To relate psychological well-being, resilience and Coping with social and clinical features of Crohn’s disease patients. METHODS: Prospective study including 104 patients with Crohn’s disease, both genders and mean age of 39 years. Standardized scales were used to assess and to relate psychological well-being, resilience and Coping with social and clinical variables. A questionnaire to characterize the sample and standardized scales in data collection (psychological well-being, resilience pillars and Coping strategies inventory - Folkman & Lazarus) were used. Descriptive analysis of data and statistics for comparison of results were performed. RESULTS: There were significant differences (P<0.05) showing better psychological well-being for male patients, those who without children, were not religious, were employed and were doing complementary activities in addition to clinical treatment. More resilience for the male gender, those who without children, were not religious, divorced, separated or widowed, that received some monthly income; who did not undergo surgery, had the first symptoms after 30 years old and who had complementary activity. There were also significant differences in the use of Coping: usually, women used more developed escape and avoidance strategies; single, married or in stable-union patients used more self-control; not religious used positive revaluation strategy; the ones who were employed showed more self-control and positive reassessment; the ones who had lower family income indicated that they used less the self-control; the ones who had higher family income used more positive re-evaluation; patients who were diagnosed with Crohn’s disease between the second decade of life showed to use mores more the positive reassessment strategy than those who were 20 years old or younger. CONCLUSION: Social aspects influenced psychological well-being, resilience and Coping in patients with Crohn’s disease more strongly than clinical aspects. It was possible to identify the profiles with better and worse psychological well-being, resilience and Coping of those who need more support, as well as to know the most used Coping strategies in the studied group.


2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S513-S514
Author(s):  
S Regev ◽  
G Goren ◽  
D Schwartz ◽  
R Sergienko ◽  
M Friger ◽  
...  

Abstract Background Medical and psychological factors contribute to the heightened psychological distress and reduced health-related quality of life in patients with Crohn’s disease. Whether Social Support plays a role in this scenario is unknown. We used the Multidimensional Scale of Perceived Social Support (MSPSS) to investigate whether Social Support associates with psychological distress and quality of life in Crohn’s disease. Methods Consecutive adult patients with Crohn’s disease, presenting at specialist gastroenterology services or recruited by advertising, with mild to moderate disease activity by the Harvey-Bradshaw Index (HBI), were enrolled into the study. Patients completed the 12-item MSPSS questionnaire that measures psychological support in three categories: Family, Friends and Significant Other, and provides individual category scores and a total score (range of all scores 1–7; a higher score indicates more social support). Patients also completed the following questionnaires: psychological distress (Brief Symptom Inventory, with Global Severity Index, GSI), quality of life (Short Inflammatory Bowel Disease Questionnaire, SIBDQ), satisfaction with life (SWLS), family stress (Family Assessment Device, FAD), coping strategies (Brief-COPE), and presenteeism and work activity (WPAI). Statistics: Spearman rho. *p&lt;0.05, **p&lt;0.01. Results The cohort comprised 126 patients, mean (SD) age 33.7 (10.6) years, females 79%, HBI 8.4 (2.5), CRP 1.2 (2.3), calprotectin 394 (674). MSPSS scores were as follows: Total score 5.72 (1.14), Friends 5.36 (1.34), Family 5.73 (1.14), and Significant Other 6.07 (1.15); Cronbach’s α ≥ .877. MSPSS scores correlated negatively with family stress measure FAD: Friends -.258**, Family -.732**, Significant Other -.401**; and with GSI psychological stress measure: Friends -305**, Family -.352**, Significant Other -.245**. MSPSS correlated positively with SIBDQ quality of life: Friends .300**, Family .188*, Significant Other .200*; and with satisfaction with life SWLS: Friends .379**, Family .333**, Significant Other .245**. MSPSS correlations with emotion-focused coping were: Friends -.337**, Family -.263**, Significant Other -.329**. MSPSS Family score correlated negatively with WPAI presenteeism -.270*, and WPAI work activity -.294**. Conclusion In mild to moderate Crohn’s disease, strong social support was associated with better quality of life, more satisfaction with life, and better performance in the work arena. Social support was associated with reduced psychological distress, reduced family stress, and less use of emotion-focused coping. This research shows the importance of social support in improving the psychological condition of patients with Crohn’s disease.


2019 ◽  
Vol 57 (04) ◽  
pp. 473-483 ◽  
Author(s):  
Vanessa Petruo ◽  
Ekaterina Krauss ◽  
Anika Kleist ◽  
Juliane Hardt ◽  
Karsten Hake ◽  
...  

Abstract Background and aims This study examined differences in personality, psychological distress, and stress coping in inflammatory bowel disease (IBD) depending on type of disease and disease activity. We compared patients suffering from Crohn’s disease (CD) and ulcerative colitis (UC) with controls. While the literature is replete with distinctive features of the pathogenesis of IBD, the specific differences in psychological impairments are not well studied. Methods In this German national multicenter study, participants were recruited from 32 centers. Two hundred ninety-seven questionnaires were included, delivering vast information on disease status and psychological well-being based on validated instruments with a total of 285 variables. Results CD patients were more affected by psychological impairments than patients suffering from UC or controls. Importantly, patients with active CD scored higher in neuroticism (p < 0.01), psychological distress (p < 0.001) and maladaptive stress coping (escape, p = 0.03; rumination, p < 0.03), but less need for social support (p = 0.001) than controls. In contrast, patients suffering from active UC showed psychological distress (p < 0.04) and maladaptive coping (avoidance, p < 0.03; escape, p = 0.01). Patients in remission seemed to be less affected. In particular, patients with UC in remission were not inflicted by psychological impairments. The group of CD patients in remission however, showed insecurity (p < 0.01) and paranoid ideation (p = 0.04). Conclusions We identified specific aspects of psychological impairment in IBD depending on disease and disease activity. Our results underscore the need for psychological support and treatment particularly in active CD.


2013 ◽  
Vol 45 ◽  
pp. S147
Author(s):  
E. Geccherle ◽  
M. Fortuna ◽  
R. Montanari ◽  
A. Geccherle ◽  
M. Chiaramonte

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